Matches in SemOpenAlex for { <https://semopenalex.org/work/W3214908296> ?p ?o ?g. }
- W3214908296 endingPage "1089" @default.
- W3214908296 startingPage "1089" @default.
- W3214908296 abstract "We aimed to review and analyse the effectiveness and safety of botulinum toxin type A (BoNT-A) injections for drooling in children with cerebral palsy.We searched the EMBASE, MEDLINE, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library) databases from inception to January 2020.We included randomized controlled trials and observational studies which (1) involved children with cerebral palsy, (2) used BoNT-A for control of drooling, and (3) provided quantitative evaluations of drooling before and after intervention with BoNT-A.Twenty-one trials met the inclusion criteria. Most studies showed that BoNT-A injections are safe and efficacious as a treatment for drooling in children with cerebral palsy. Four trials had sufficient data to pool the results for the meta-analysis. Both the drooling quotient (p = 0.002) and drooling Ffrequency and severity scale (p = 0.004) supported this conclusion.BoNT-A injections are a safe, reversible, effective treatment for drooling control in children with cerebral palsy that can offer effectiveness for more than 3 months with few side effects. The dosage of BoNT-A should not exceed 4 units/kg. Further studies are required to determine the optimal dosage and target glands." @default.
- W3214908296 created "2021-12-06" @default.
- W3214908296 creator A5036472924 @default.
- W3214908296 creator A5044739073 @default.
- W3214908296 creator A5049890555 @default.
- W3214908296 creator A5050729139 @default.
- W3214908296 creator A5070648053 @default.
- W3214908296 creator A5079536975 @default.
- W3214908296 date "2021-11-25" @default.
- W3214908296 modified "2023-10-13" @default.
- W3214908296 title "Botulinum Toxin Injections for Treatment of Drooling in Children with Cerebral Palsy: A Systematic Review and Meta-Analysis" @default.
- W3214908296 cites W1491787117 @default.
- W3214908296 cites W1523767897 @default.
- W3214908296 cites W1524049089 @default.
- W3214908296 cites W1534725609 @default.
- W3214908296 cites W1570211782 @default.
- W3214908296 cites W1582652007 @default.
- W3214908296 cites W1582690621 @default.
- W3214908296 cites W1604165579 @default.
- W3214908296 cites W1685560163 @default.
- W3214908296 cites W1799814383 @default.
- W3214908296 cites W1894910337 @default.
- W3214908296 cites W1917932409 @default.
- W3214908296 cites W1954367838 @default.
- W3214908296 cites W1969516105 @default.
- W3214908296 cites W1969839688 @default.
- W3214908296 cites W1972706130 @default.
- W3214908296 cites W1973167500 @default.
- W3214908296 cites W1979447816 @default.
- W3214908296 cites W1985837698 @default.
- W3214908296 cites W1992327462 @default.
- W3214908296 cites W2000708211 @default.
- W3214908296 cites W2009330277 @default.
- W3214908296 cites W2024894487 @default.
- W3214908296 cites W2027081191 @default.
- W3214908296 cites W2045717919 @default.
- W3214908296 cites W2047985343 @default.
- W3214908296 cites W2050956308 @default.
- W3214908296 cites W2056695942 @default.
- W3214908296 cites W2072725160 @default.
- W3214908296 cites W2078413807 @default.
- W3214908296 cites W2081682569 @default.
- W3214908296 cites W2085746159 @default.
- W3214908296 cites W2086243180 @default.
- W3214908296 cites W2090018499 @default.
- W3214908296 cites W2101385208 @default.
- W3214908296 cites W2101639093 @default.
- W3214908296 cites W2102565461 @default.
- W3214908296 cites W2105955941 @default.
- W3214908296 cites W2112199541 @default.
- W3214908296 cites W2114817153 @default.
- W3214908296 cites W2122504018 @default.
- W3214908296 cites W2123811803 @default.
- W3214908296 cites W2142409735 @default.
- W3214908296 cites W2153531851 @default.
- W3214908296 cites W2169183345 @default.
- W3214908296 cites W2181702034 @default.
- W3214908296 cites W2181841001 @default.
- W3214908296 cites W2288546638 @default.
- W3214908296 cites W2409907460 @default.
- W3214908296 cites W2608444233 @default.
- W3214908296 cites W2885088634 @default.
- W3214908296 cites W2894901018 @default.
- W3214908296 cites W2912353951 @default.
- W3214908296 cites W2922036669 @default.
- W3214908296 cites W2948162169 @default.
- W3214908296 cites W2970738533 @default.
- W3214908296 cites W745796678 @default.
- W3214908296 doi "https://doi.org/10.3390/children8121089" @default.
- W3214908296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34943284" @default.
- W3214908296 hasPublicationYear "2021" @default.
- W3214908296 type Work @default.
- W3214908296 sameAs 3214908296 @default.
- W3214908296 citedByCount "9" @default.
- W3214908296 countsByYear W32149082962022 @default.
- W3214908296 countsByYear W32149082962023 @default.
- W3214908296 crossrefType "journal-article" @default.
- W3214908296 hasAuthorship W3214908296A5036472924 @default.
- W3214908296 hasAuthorship W3214908296A5044739073 @default.
- W3214908296 hasAuthorship W3214908296A5049890555 @default.
- W3214908296 hasAuthorship W3214908296A5050729139 @default.
- W3214908296 hasAuthorship W3214908296A5070648053 @default.
- W3214908296 hasAuthorship W3214908296A5079536975 @default.
- W3214908296 hasBestOaLocation W32149082961 @default.
- W3214908296 hasConcept C126322002 @default.
- W3214908296 hasConcept C141071460 @default.
- W3214908296 hasConcept C142724271 @default.
- W3214908296 hasConcept C168563851 @default.
- W3214908296 hasConcept C1862650 @default.
- W3214908296 hasConcept C187212893 @default.
- W3214908296 hasConcept C204787440 @default.
- W3214908296 hasConcept C2776478404 @default.
- W3214908296 hasConcept C2776796639 @default.
- W3214908296 hasConcept C2777478456 @default.
- W3214908296 hasConcept C2777596629 @default.
- W3214908296 hasConcept C2779421357 @default.
- W3214908296 hasConcept C42219234 @default.
- W3214908296 hasConcept C71924100 @default.