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- W3215046974 abstract "Peripheral artery disease (PAD) is a serious public health issue, characterized by circulation disorder of the lower extreme that reduces the physical activity of the lower extremity muscle. The artery narrowed by atherosclerotic lesions initiates limb ischemia. In the progression of treatment, reperfusion injury is still inevitable. Ischemia-reperfusion injury induced by PAD is responsible for hypoxia and nutrient deficiency. PAD triggers hindlimb ischemia and reperfusion (I/R) cycles through various mechanisms, mainly including mitochondrial dysfunction and inflammation. Alternatively, mitochondrial dysfunction plays a central role. The I/R injury may cause cells’ injury and even death. However, the mechanism of I/R injury and the way of cell damage or death are still unclear. We review the pathophysiology of I/R injury, which is majorly about mitochondrial dysfunction. Then, we focus on the cell damage and death during I/R injury. Further comprehension of the progress of I/R will help identify biomarkers for diagnosis and therapeutic targets to PAD. In addition, traditional Chinese medicine has played an important role in the treatment of I/R injury, and we will make a brief introduction." @default.
- W3215046974 created "2021-12-06" @default.
- W3215046974 creator A5024180768 @default.
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- W3215046974 creator A5067798266 @default.
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- W3215046974 creator A5089732894 @default.
- W3215046974 date "2021-12-02" @default.
- W3215046974 modified "2023-09-26" @default.
- W3215046974 title "Ischemia-Reperfusion Injury in Peripheral Artery Disease and Traditional Chinese Medicine Treatment" @default.
- W3215046974 cites W1042476336 @default.
- W3215046974 cites W1507516689 @default.
- W3215046974 cites W1520365933 @default.
- W3215046974 cites W1563439029 @default.
- W3215046974 cites W1968081526 @default.
- W3215046974 cites W1972557061 @default.
- W3215046974 cites W1972621186 @default.
- W3215046974 cites W1989026904 @default.
- W3215046974 cites W1989528047 @default.
- W3215046974 cites W1989562776 @default.
- W3215046974 cites W1992789370 @default.
- W3215046974 cites W1998539678 @default.
- W3215046974 cites W2000205368 @default.
- W3215046974 cites W2000650296 @default.
- W3215046974 cites W2001610514 @default.
- W3215046974 cites W2001682169 @default.
- W3215046974 cites W2001924380 @default.
- W3215046974 cites W2006090847 @default.
- W3215046974 cites W2014336636 @default.
- W3215046974 cites W2014649168 @default.
- W3215046974 cites W2018963148 @default.
- W3215046974 cites W2020396176 @default.
- W3215046974 cites W2020430913 @default.
- W3215046974 cites W2023195304 @default.
- W3215046974 cites W2024858284 @default.
- W3215046974 cites W2026660662 @default.
- W3215046974 cites W2027073131 @default.
- W3215046974 cites W2034630481 @default.
- W3215046974 cites W2036276523 @default.
- W3215046974 cites W2040716650 @default.
- W3215046974 cites W2041283853 @default.
- W3215046974 cites W2042851093 @default.
- W3215046974 cites W2051343325 @default.
- W3215046974 cites W2051940924 @default.
- W3215046974 cites W2052440346 @default.
- W3215046974 cites W2053855194 @default.
- W3215046974 cites W2055251180 @default.
- W3215046974 cites W2055316379 @default.
- W3215046974 cites W2059479985 @default.
- W3215046974 cites W2060160559 @default.
- W3215046974 cites W2062724438 @default.
- W3215046974 cites W2071508682 @default.
- W3215046974 cites W2072805330 @default.
- W3215046974 cites W2076378891 @default.
- W3215046974 cites W2076574120 @default.
- W3215046974 cites W2081199500 @default.
- W3215046974 cites W2081894934 @default.
- W3215046974 cites W2083884362 @default.
- W3215046974 cites W2092566326 @default.
- W3215046974 cites W2093453769 @default.
- W3215046974 cites W2097005995 @default.
- W3215046974 cites W2102538589 @default.
- W3215046974 cites W2115672146 @default.
- W3215046974 cites W2121423505 @default.
- W3215046974 cites W2124032393 @default.
- W3215046974 cites W2125419124 @default.
- W3215046974 cites W2128809832 @default.
- W3215046974 cites W2129932871 @default.
- W3215046974 cites W2134710242 @default.
- W3215046974 cites W2136648677 @default.
- W3215046974 cites W2142384233 @default.
- W3215046974 cites W2143626424 @default.
- W3215046974 cites W2151611702 @default.
- W3215046974 cites W2153610289 @default.
- W3215046974 cites W2169365673 @default.
- W3215046974 cites W2170015173 @default.
- W3215046974 cites W2171362450 @default.
- W3215046974 cites W2189353323 @default.
- W3215046974 cites W2210151709 @default.
- W3215046974 cites W2257349628 @default.
- W3215046974 cites W2329808869 @default.
- W3215046974 cites W2334626732 @default.
- W3215046974 cites W2401288519 @default.
- W3215046974 cites W2460479205 @default.
- W3215046974 cites W2519194796 @default.
- W3215046974 cites W2552063923 @default.
- W3215046974 cites W2558659314 @default.
- W3215046974 cites W2568039323 @default.
- W3215046974 cites W2612956841 @default.
- W3215046974 cites W2624701219 @default.
- W3215046974 cites W2735250338 @default.
- W3215046974 cites W2755875967 @default.
- W3215046974 cites W2790553322 @default.
- W3215046974 cites W2802537586 @default.
- W3215046974 cites W2894273957 @default.
- W3215046974 cites W2911871245 @default.