Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215272712> ?p ?o ?g. }
- W3215272712 endingPage "0" @default.
- W3215272712 startingPage "0" @default.
- W3215272712 abstract "The purpose of this study was to evaluate the expression of MMP-12 in patients with chronic rhinosinusitis with polyps (CRSwNP).Tissue samples from 37 patients with CRSwNP undergoing functional endoscopic sinus surgery and healthy mucosa specimens from 12 healthy controls were obtained intraoperatively. The mRNA and protein expression levels of MMP-12 were quantified by real-time polymerase chain reaction and Western blotting, respectively.mRNA levels of MMP-12 were significantly elevated in the CRSwNP tissue samples compared to those in control ones. The protein levels of MMP-12 showed a trend of increasing but with no statistical significance.Elevation of MMP-12 in patients with CRSwNP suggests its potential implication in the pathogenesis of the disease. The difference in the expression profile observed between mRNA and protein levels could be due to post-translational gene expression regulation. Our findings provide evidence that MMP-12 along with other MMPs may serve as a biomarker and therapeutic target in the management of the disease." @default.
- W3215272712 created "2021-12-06" @default.
- W3215272712 creator A5021478101 @default.
- W3215272712 creator A5025922629 @default.
- W3215272712 creator A5028120082 @default.
- W3215272712 creator A5069750777 @default.
- W3215272712 creator A5071769539 @default.
- W3215272712 creator A5074354699 @default.
- W3215272712 creator A5081183150 @default.
- W3215272712 date "2021-11-23" @default.
- W3215272712 modified "2023-10-17" @default.
- W3215272712 title "Evaluation of MMP-12 expression in chronic rhinosinusitis with nasal polyposis" @default.
- W3215272712 cites W1487359600 @default.
- W3215272712 cites W1545521314 @default.
- W3215272712 cites W1965498876 @default.
- W3215272712 cites W1971040121 @default.
- W3215272712 cites W1975316938 @default.
- W3215272712 cites W1978596588 @default.
- W3215272712 cites W1986511164 @default.
- W3215272712 cites W1988056340 @default.
- W3215272712 cites W2004556227 @default.
- W3215272712 cites W2021359366 @default.
- W3215272712 cites W2031654076 @default.
- W3215272712 cites W2042391758 @default.
- W3215272712 cites W2042444534 @default.
- W3215272712 cites W2048554743 @default.
- W3215272712 cites W2050620145 @default.
- W3215272712 cites W2067922574 @default.
- W3215272712 cites W2087025056 @default.
- W3215272712 cites W2087377443 @default.
- W3215272712 cites W2096759470 @default.
- W3215272712 cites W2099969611 @default.
- W3215272712 cites W2107277218 @default.
- W3215272712 cites W2108271602 @default.
- W3215272712 cites W2109191037 @default.
- W3215272712 cites W2112801222 @default.
- W3215272712 cites W2115850430 @default.
- W3215272712 cites W2124698558 @default.
- W3215272712 cites W2154239113 @default.
- W3215272712 cites W2157102252 @default.
- W3215272712 cites W2165726810 @default.
- W3215272712 cites W2271709632 @default.
- W3215272712 cites W2464333097 @default.
- W3215272712 cites W2783759757 @default.
- W3215272712 cites W2905586585 @default.
- W3215272712 cites W2906663276 @default.
- W3215272712 cites W2981916751 @default.
- W3215272712 cites W2998589641 @default.
- W3215272712 cites W3046555425 @default.
- W3215272712 cites W3093096926 @default.
- W3215272712 doi "https://doi.org/10.4193/rhin21.320" @default.
- W3215272712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34812434" @default.
- W3215272712 hasPublicationYear "2021" @default.
- W3215272712 type Work @default.
- W3215272712 sameAs 3215272712 @default.
- W3215272712 citedByCount "1" @default.
- W3215272712 countsByYear W32152727122022 @default.
- W3215272712 crossrefType "journal-article" @default.
- W3215272712 hasAuthorship W3215272712A5021478101 @default.
- W3215272712 hasAuthorship W3215272712A5025922629 @default.
- W3215272712 hasAuthorship W3215272712A5028120082 @default.
- W3215272712 hasAuthorship W3215272712A5069750777 @default.
- W3215272712 hasAuthorship W3215272712A5071769539 @default.
- W3215272712 hasAuthorship W3215272712A5074354699 @default.
- W3215272712 hasAuthorship W3215272712A5081183150 @default.
- W3215272712 hasConcept C104317684 @default.
- W3215272712 hasConcept C105580179 @default.
- W3215272712 hasConcept C109523444 @default.
- W3215272712 hasConcept C126322002 @default.
- W3215272712 hasConcept C141071460 @default.
- W3215272712 hasConcept C142724271 @default.
- W3215272712 hasConcept C150194340 @default.
- W3215272712 hasConcept C203014093 @default.
- W3215272712 hasConcept C2777768476 @default.
- W3215272712 hasConcept C2778117937 @default.
- W3215272712 hasConcept C2780942790 @default.
- W3215272712 hasConcept C2781197716 @default.
- W3215272712 hasConcept C2781390199 @default.
- W3215272712 hasConcept C2993524501 @default.
- W3215272712 hasConcept C3019717275 @default.
- W3215272712 hasConcept C48023723 @default.
- W3215272712 hasConcept C55493867 @default.
- W3215272712 hasConcept C63363279 @default.
- W3215272712 hasConcept C71924100 @default.
- W3215272712 hasConcept C85265743 @default.
- W3215272712 hasConcept C86803240 @default.
- W3215272712 hasConcept C90924648 @default.
- W3215272712 hasConceptScore W3215272712C104317684 @default.
- W3215272712 hasConceptScore W3215272712C105580179 @default.
- W3215272712 hasConceptScore W3215272712C109523444 @default.
- W3215272712 hasConceptScore W3215272712C126322002 @default.
- W3215272712 hasConceptScore W3215272712C141071460 @default.
- W3215272712 hasConceptScore W3215272712C142724271 @default.
- W3215272712 hasConceptScore W3215272712C150194340 @default.
- W3215272712 hasConceptScore W3215272712C203014093 @default.
- W3215272712 hasConceptScore W3215272712C2777768476 @default.
- W3215272712 hasConceptScore W3215272712C2778117937 @default.
- W3215272712 hasConceptScore W3215272712C2780942790 @default.