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- W3215317480 abstract "This study investigated the relationship between fractional exhaled nitric oxide (FeNO) in hospitalized and in post-COVID-19 patients. The present study evaluated the possible FeNO variations in hospitalized and in post-COVID-19 patients of different severities and demonstrate the importance of FeNO as a possible biomarker for COVID-19. Five patients’ groups were studied: Non-COVID-19 patients (n=21), Hospitalized Severe COVID-19 patients (n=28), Mild Post-COVID-19 patients (n=75), Moderate Post-COVID-19 patients (n=33), Severe Post-COVID-19 patients (n=20). Post-COVID-19 were evaluated between 3-15 days after hospital discharge. FeNO levels were measured by using NoBreath monitor (Bedfont Scientific, UK). We observed reduced levels of FeNO in hospitalized severe COVID-19 patients (7,81±3,17ppb; p<0.01) compared to non-COVID-19 patients (22,55±14,65ppb), Mild Post-COVID-19 (15,53±9,35ppb; p<0.01) compared to non-COVID-19 patients, Moderate COVID-19 (16,84±7,93ppb; p<0.01) compared with non-COVID-19 patients, Severe COVID-19 patients (13,75±6,37ppb; p<0.01) compared to non-COVID-19 patients. No differences were found comparing Mild x Moderate and Mild x Severe and Moderate x Severe post-COVID-19 patients. Therefore, the results clearly demonstrated that eNO levels are reduced in hospitalized COVID-19 patients and its remained reduced for until 15 days after hospital discharge. Of note, the literature already demonstrated that reduced bioavailability of nitric oxide is closely related to reduced lung and cardiovascular function. So, we conclude that lower levels of eNO may be a biomarker of infection for Sars-Cov-2." @default.
- W3215317480 created "2021-12-06" @default.
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- W3215317480 date "2021-09-05" @default.
- W3215317480 modified "2023-10-14" @default.
- W3215317480 title "Can Exhaled Nitric Oxide Be a Biomarker for Hospitalized and Post-COVID-19 Patients?" @default.
- W3215317480 doi "https://doi.org/10.1183/13993003.congress-2021.pa3884" @default.
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