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- W3215536639 endingPage "1166" @default.
- W3215536639 startingPage "1156" @default.
- W3215536639 abstract "Diabetes mellitus is a chronic disease characterized by increased blood glucose levels, leading to damage of the nerves blood vessels, subsequently manifesting as organ failures, wounds, or ulcerations. Wounds in patients with diabetes are further complicated because of reduced cytokine responses, infection, poor vascularization, and delayed healing processes. Surface-functionalized and bioengineered nanoparticles (NPs) have recently gained attention as emerging treatment modalities for wound healing in diabetes. Here, we review emerging therapeutic NPs to treat diabetic wounds and highlight their discrete delivery mechanisms and sites of action. We further critically assess the current challenges of these nanoengineered materials for successful clinical translation and discuss their potential for growth in the clinical marketplace." @default.
- W3215536639 created "2021-12-06" @default.
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- W3215536639 date "2022-04-01" @default.
- W3215536639 modified "2023-10-16" @default.
- W3215536639 title "Engineering nanoparticle therapeutics for impaired wound healing in diabetes" @default.
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- W3215536639 doi "https://doi.org/10.1016/j.drudis.2021.11.024" @default.
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