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• W3215593846 abstract "To identify clinical and radiological factors associated to early evolution to brain death (BD), defined as occurring within the first 24 h.A retrospective cohort study was made covering the period 2015-2017.An adult Intensive Care Unit (ICU).Epidemiological, clinical and imaging (CT scan) parameters upon admission to the ICU in patients evolving to BD.A total of 166 patients with BD (86 males, mean age 62.7 years) were analyzed. Primary cause: intracerebral hemorrhage 42.8%, subarachnoid hemorrhage 18.7%, traumatic brain injury 17.5%, anoxia 9%, stroke 7.8%, other causes 4.2%. Epidemiological data: arterial hypertension 50%, dyslipidemia 34%, smoking 33%, antiplatelet medication 21%, alcoholism 19%, anticoagulant therapy 15%, diabetes 15%. The Glasgow Coma Score (GCS) upon admission was 3 in 68.8% of the cases in early BD versus in 38.2% of the cases in BD occurring after 24 h (p = 0.0001). Eighty-five patients presented supratentorial hematomas with a volume of 90.9 ml in early BD versus 82.7 ml in BD > 24 h (p = 0.54). The mean midline shift was 10.7 mm in early BD versus 7.8 mm in BD > 24 h (p = 0.045). Ninety-one patients presented ventriculomegaly and 38 additionally ependymal transudation (p = 0.021). Thirty-six patients with early BD versus 24 with BD > 24 h presented complete effacement of basal cisterns (p = 0.005), sulcular effacement (p = 0.013), loss of cortico-subcortical differentiation (p = 0.0001) and effacement of the suprasellar cistern (p = 0.005). The optic nerve sheath measurements showed no significant differences between groups.Early BD (>24 h) was associated to GCS < 5, midline shift, effacement of the basal cisterns, cerebral sulci and suprasellar cistern, and ependymal transudation." @default.
• W3215593846 created "2021-12-06" @default.
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• W3215593846 date "2022-01-01" @default.
• W3215593846 modified "2023-10-18" @default.
• W3215593846 title "Clinico-radiological related to early brain death factors" @default.
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• W3215593846 doi "https://doi.org/10.1016/j.medine.2021.11.005" @default.
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