Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215636775> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3215636775 endingPage "e000514" @default.
- W3215636775 startingPage "e000514" @default.
- W3215636775 abstract "Objective Epidemiological studies have shown that discoid lupus erythematosus (DLE) has a higher incidence and prevalence in racial/ethnic minority groups, particularly Black individuals. The objective of this retrospective cohort study was to identify the differences in DLE lesion distribution and characteristics in Black individuals compared with non-Black individuals. Methods 183 patients with DLE (112 Black patients and 71 non-Black patients) with a reported race/ethnicity and Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) scores were included in this retrospective cohort study. Univariate analysis was performed to determine significant differences in demographic data, clinical characteristics, DLE lesion distribution and DLE lesion characteristics in Black and non-Black patients with DLE. Multivariable logistic regression was preformed to determine significant predictors of DLE lesion location and characteristics. Results Black patients with DLE had worse baseline CLASI damage scores compared with non-Black patients with DLE (median (IQR): 10.0 (6.0–14.5) vs 6.0 (3.0–10.0), p<0.001) and had 48.9 greater odds of dyspigmentation in any anatomical location (p<0.001). Black patients had 2.54 greater odds of having scalp involvement (p=0.015) and 1.97 greater odds of having ear involvement (p=0.032) compared with non-Black patients. Black patients also had greater odds of scalp dyspigmentation (OR=5.85, p<0.001), ear dyspigmentation (OR=2.89, p=0.001) and scarring alopecia (OR=3.00, p=0.001) compared with non-Black patients. Conclusions Signs of disease damage, particularly ear dyspigmentation, scalp dyspigmentation and scarring alopecia, can more frequently affect Black patients with DLE. Recognising differences in clinical presentation of DLE among Black patients can assist future efforts with understanding biological, cultural, psychosocial and systemic factors that influence DLE presentation and outcomes in Black patients and may guide clinicians when counselling Black patients." @default.
- W3215636775 created "2021-12-06" @default.
- W3215636775 creator A5013743459 @default.
- W3215636775 creator A5027193363 @default.
- W3215636775 creator A5031229808 @default.
- W3215636775 creator A5047313225 @default.
- W3215636775 date "2021-11-01" @default.
- W3215636775 modified "2023-10-10" @default.
- W3215636775 title "Discoid lupus erythematosus skin lesion distribution and characteristics in Black patients: a retrospective cohort study" @default.
- W3215636775 cites W2009528646 @default.
- W3215636775 cites W2047342378 @default.
- W3215636775 cites W2080150944 @default.
- W3215636775 cites W2338510796 @default.
- W3215636775 cites W2800471232 @default.
- W3215636775 cites W2898325776 @default.
- W3215636775 cites W2911630412 @default.
- W3215636775 cites W2969803043 @default.
- W3215636775 cites W2982328316 @default.
- W3215636775 cites W3094350968 @default.
- W3215636775 cites W3142157418 @default.
- W3215636775 cites W1888090543 @default.
- W3215636775 doi "https://doi.org/10.1136/lupus-2021-000514" @default.
- W3215636775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34853149" @default.
- W3215636775 hasPublicationYear "2021" @default.
- W3215636775 type Work @default.
- W3215636775 sameAs 3215636775 @default.
- W3215636775 citedByCount "9" @default.
- W3215636775 countsByYear W32156367752022 @default.
- W3215636775 countsByYear W32156367752023 @default.
- W3215636775 crossrefType "journal-article" @default.
- W3215636775 hasAuthorship W3215636775A5013743459 @default.
- W3215636775 hasAuthorship W3215636775A5027193363 @default.
- W3215636775 hasAuthorship W3215636775A5031229808 @default.
- W3215636775 hasAuthorship W3215636775A5047313225 @default.
- W3215636775 hasBestOaLocation W32156367751 @default.
- W3215636775 hasConcept C107130276 @default.
- W3215636775 hasConcept C126322002 @default.
- W3215636775 hasConcept C141071460 @default.
- W3215636775 hasConcept C156957248 @default.
- W3215636775 hasConcept C159654299 @default.
- W3215636775 hasConcept C16005928 @default.
- W3215636775 hasConcept C167135981 @default.
- W3215636775 hasConcept C203014093 @default.
- W3215636775 hasConcept C2775915377 @default.
- W3215636775 hasConcept C2776748653 @default.
- W3215636775 hasConcept C2781156865 @default.
- W3215636775 hasConcept C71924100 @default.
- W3215636775 hasConcept C72563966 @default.
- W3215636775 hasConceptScore W3215636775C107130276 @default.
- W3215636775 hasConceptScore W3215636775C126322002 @default.
- W3215636775 hasConceptScore W3215636775C141071460 @default.
- W3215636775 hasConceptScore W3215636775C156957248 @default.
- W3215636775 hasConceptScore W3215636775C159654299 @default.
- W3215636775 hasConceptScore W3215636775C16005928 @default.
- W3215636775 hasConceptScore W3215636775C167135981 @default.
- W3215636775 hasConceptScore W3215636775C203014093 @default.
- W3215636775 hasConceptScore W3215636775C2775915377 @default.
- W3215636775 hasConceptScore W3215636775C2776748653 @default.
- W3215636775 hasConceptScore W3215636775C2781156865 @default.
- W3215636775 hasConceptScore W3215636775C71924100 @default.
- W3215636775 hasConceptScore W3215636775C72563966 @default.
- W3215636775 hasFunder F4320337362 @default.
- W3215636775 hasIssue "1" @default.
- W3215636775 hasLocation W32156367751 @default.
- W3215636775 hasLocation W32156367752 @default.
- W3215636775 hasLocation W32156367753 @default.
- W3215636775 hasLocation W32156367754 @default.
- W3215636775 hasOpenAccess W3215636775 @default.
- W3215636775 hasPrimaryLocation W32156367751 @default.
- W3215636775 hasRelatedWork W1547159227 @default.
- W3215636775 hasRelatedWork W1967229968 @default.
- W3215636775 hasRelatedWork W1969704510 @default.
- W3215636775 hasRelatedWork W2005218498 @default.
- W3215636775 hasRelatedWork W2084640129 @default.
- W3215636775 hasRelatedWork W2137063551 @default.
- W3215636775 hasRelatedWork W2219370219 @default.
- W3215636775 hasRelatedWork W2922354564 @default.
- W3215636775 hasRelatedWork W3089381123 @default.
- W3215636775 hasRelatedWork W80550898 @default.
- W3215636775 hasVolume "8" @default.
- W3215636775 isParatext "false" @default.
- W3215636775 isRetracted "false" @default.
- W3215636775 magId "3215636775" @default.
- W3215636775 workType "article" @default.