FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215661978> ?p ?o ?g. }

• W3215661978 endingPage "305" @default.
• W3215661978 startingPage "295" @default.
• W3215661978 abstract "Naringenin (4′,5,7-trihydroxyflavanone-7-rhamnoglucosideor naringenin-7-rhamnoglucoside), a flavonoid present in large quantities in citrus, has different beneficial effects on human health as an antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. Different studies have shown that this substance also has a hypoglycemic and antihypertensive effect, reduces cholesterol and triglycerides, and plays an important protective role in the heart tissue; moreover, it provides neuroprotection against various neurological disorders such as Parkinson’s disease and unpredictable chronic stress-induced depression. Despite these advantages, Naringenin is poorly absorbed, and the small percentage absorbed is rapidly degraded by the liver, as a result losing its activity. Several approaches have been attempted to overcome these obstacles, among them, nanotechnology, with the use of Drug Delivery Systems (DDS) as Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC). DDS can, in fact, improve the drug bioavailability. The aim of this study was to develop and characterize SLN and NLC containing Naringenin and to evaluate the ability of these nanoparticles to release Naringenin at the cell level using biomembrane models represented by Multilamellar Vesicles (MLV). These studies were performed using Differential Scanning Calorimetry, a powerful technique to detect the interaction of drugs and delivery systems with MLV. It was shown that Naringenin could be better incorporated into NLC with respect to SLN and that Naringenin could be released by NLC into the biomembrane model. Therefore, suggesting the administration of Naringenin loaded into nanoparticles could help avoid the disadvantages associated with the use of the free molecule." @default.
• W3215661978 created "2021-12-06" @default.
• W3215661978 creator A5012323219 @default.
• W3215661978 creator A5046448430 @default.
• W3215661978 creator A5049703091 @default.
• W3215661978 creator A5059574925 @default.
• W3215661978 date "2021-11-29" @default.
• W3215661978 modified "2023-09-26" @default.
• W3215661978 title "Naringenin Release to Biomembrane Models by Incorporation into Nanoparticles. Experimental Evidence Using Differential Scanning Calorimetry" @default.
• W3215661978 cites W1980683111 @default.
• W3215661978 cites W2002268664 @default.
• W3215661978 cites W2007765995 @default.
• W3215661978 cites W2008357186 @default.
• W3215661978 cites W2013638808 @default.
• W3215661978 cites W2013912675 @default.
• W3215661978 cites W2016568983 @default.
• W3215661978 cites W2027815523 @default.
• W3215661978 cites W2054189154 @default.
• W3215661978 cites W2057000237 @default.
• W3215661978 cites W2059520952 @default.
• W3215661978 cites W2076080083 @default.
• W3215661978 cites W2092661856 @default.
• W3215661978 cites W2131566674 @default.
• W3215661978 cites W2137461654 @default.
• W3215661978 cites W2333376526 @default.
• W3215661978 cites W2346901331 @default.
• W3215661978 cites W2620373091 @default.
• W3215661978 cites W2769630278 @default.
• W3215661978 cites W2790630937 @default.
• W3215661978 cites W2896399282 @default.
• W3215661978 cites W2914440426 @default.
• W3215661978 cites W2942597185 @default.
• W3215661978 cites W2943649466 @default.
• W3215661978 cites W3083901824 @default.
• W3215661978 cites W3129923343 @default.
• W3215661978 cites W3152685356 @default.
• W3215661978 doi "https://doi.org/10.3390/surfaces4040025" @default.
• W3215661978 hasPublicationYear "2021" @default.
• W3215661978 type Work @default.
• W3215661978 sameAs 3215661978 @default.
• W3215661978 citedByCount "3" @default.
• W3215661978 countsByYear W32156619782022 @default.
• W3215661978 countsByYear W32156619782023 @default.
• W3215661978 crossrefType "journal-article" @default.
• W3215661978 hasAuthorship W3215661978A5012323219 @default.
• W3215661978 hasAuthorship W3215661978A5046448430 @default.
• W3215661978 hasAuthorship W3215661978A5049703091 @default.
• W3215661978 hasAuthorship W3215661978A5059574925 @default.
• W3215661978 hasBestOaLocation W32156619781 @default.
• W3215661978 hasConcept C121332964 @default.
• W3215661978 hasConcept C12554922 @default.
• W3215661978 hasConcept C178790620 @default.
• W3215661978 hasConcept C181389837 @default.
• W3215661978 hasConcept C185154212 @default.
• W3215661978 hasConcept C185592680 @default.
• W3215661978 hasConcept C199529486 @default.
• W3215661978 hasConcept C25498285 @default.
• W3215661978 hasConcept C2776848411 @default.
• W3215661978 hasConcept C2778004101 @default.
• W3215661978 hasConcept C2779054382 @default.
• W3215661978 hasConcept C2779820397 @default.
• W3215661978 hasConcept C39519442 @default.
• W3215661978 hasConcept C55493867 @default.
• W3215661978 hasConcept C71924100 @default.
• W3215661978 hasConcept C86803240 @default.
• W3215661978 hasConcept C97355855 @default.
• W3215661978 hasConcept C98274493 @default.
• W3215661978 hasConceptScore W3215661978C121332964 @default.
• W3215661978 hasConceptScore W3215661978C12554922 @default.
• W3215661978 hasConceptScore W3215661978C178790620 @default.
• W3215661978 hasConceptScore W3215661978C181389837 @default.
• W3215661978 hasConceptScore W3215661978C185154212 @default.
• W3215661978 hasConceptScore W3215661978C185592680 @default.
• W3215661978 hasConceptScore W3215661978C199529486 @default.
• W3215661978 hasConceptScore W3215661978C25498285 @default.
• W3215661978 hasConceptScore W3215661978C2776848411 @default.
• W3215661978 hasConceptScore W3215661978C2778004101 @default.
• W3215661978 hasConceptScore W3215661978C2779054382 @default.
• W3215661978 hasConceptScore W3215661978C2779820397 @default.
• W3215661978 hasConceptScore W3215661978C39519442 @default.
• W3215661978 hasConceptScore W3215661978C55493867 @default.
• W3215661978 hasConceptScore W3215661978C71924100 @default.
• W3215661978 hasConceptScore W3215661978C86803240 @default.
• W3215661978 hasConceptScore W3215661978C97355855 @default.
• W3215661978 hasConceptScore W3215661978C98274493 @default.
• W3215661978 hasIssue "4" @default.
• W3215661978 hasLocation W32156619781 @default.
• W3215661978 hasLocation W32156619782 @default.
• W3215661978 hasOpenAccess W3215661978 @default.
• W3215661978 hasPrimaryLocation W32156619781 @default.
• W3215661978 hasRelatedWork W2007893172 @default.
• W3215661978 hasRelatedWork W2346901331 @default.
• W3215661978 hasRelatedWork W2692754402 @default.
• W3215661978 hasRelatedWork W2886831783 @default.
• W3215661978 hasRelatedWork W2905229301 @default.
• W3215661978 hasRelatedWork W2907895483 @default.
• W3215661978 hasRelatedWork W2924786537 @default.
• W3215661978 hasRelatedWork W3127260144 @default.

• next