Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215677538> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3215677538 endingPage "62" @default.
- W3215677538 startingPage "58" @default.
- W3215677538 abstract "Relevance. Traumatic and ischemic injury of the limbs is accompanied by damage of the skeletal muscles and peripheral nerves of the limbs. The dynamics and consequences of ischemic lesions remain poorly understood and need to be corrected.
 Objective: using quantitative morphological and sonographic methods, to study the dynamics of skeletal muscle damage of the limb after traumatically induced ischemia with and without the injection of platelet-rich plasma, bone marrow aspirate, and adipose tissue fraction.
 Materials and Methods. In 3 experiments, rabbits were modeled with 6-hour limb ischemia by applying an elastic tourniquet. After compartment syndrome detection, based on the assessment of subfascial pressure, cell suspensions were injected into the leg muscles. Sonographic and histological examination of the muscles was performed on days 5, 15, and 30. The results of sonography and morphometry were evaluated by statistical methods.
 Results. The developed model of ischemia consists of 6-hour immobilization of the limb, on тwhich medical elastic tourniquets were imposing. The action of the tourniquets causes high subfascial pressure and necrosis of the superficial muscle groups of the lower third of the thigh and lower leg. According to sonography, the δ-entropy of damaged tissues on day 5 is reduced relative to the intact limb, as in the case of administration of bone marrow aspirate cells. On days 15 and 30, sonography showed no difference between the comparison groups. The dynamics of morphological features of limb tissue damage consist of necrosis of superficial muscle groups, atrophy in the middle layers, and almost intact deep muscle groups. Necrosis was replaced by scar tissue, the density of which increases 11-14 times, and does not differ in the period 5-30 days. The administration of platelet plasma, bone marrow aspirate, and adipose tissue fraction did not change the dynamics of fibrotic changes in ischemic damaged muscles. Muscle atrophy is accompanied by activation of endogenous repair of single muscle fibers, which tended to intensify after injection of bone marrow aspirate. The sciatic nerve of the injured limb was not structurally damaged according to the deep topography, while the nerves of the tibia develop degenerative changes from the 15th day." @default.
- W3215677538 created "2021-12-06" @default.
- W3215677538 creator A5004476106 @default.
- W3215677538 date "2021-10-12" @default.
- W3215677538 modified "2023-10-17" @default.
- W3215677538 title "Damages of Neuromuscular System After Mechanical-Induced Limb Ischemia (Experimental Study)" @default.
- W3215677538 cites W1563952176 @default.
- W3215677538 cites W2063601357 @default.
- W3215677538 cites W2063816036 @default.
- W3215677538 cites W2073505957 @default.
- W3215677538 cites W2113306211 @default.
- W3215677538 cites W2158102739 @default.
- W3215677538 cites W2166531590 @default.
- W3215677538 cites W2787419230 @default.
- W3215677538 cites W2902541532 @default.
- W3215677538 cites W2954323249 @default.
- W3215677538 cites W3180372474 @default.
- W3215677538 doi "https://doi.org/10.37647/0132-2486-2021-109-2-58-62" @default.
- W3215677538 hasPublicationYear "2021" @default.
- W3215677538 type Work @default.
- W3215677538 sameAs 3215677538 @default.
- W3215677538 citedByCount "0" @default.
- W3215677538 crossrefType "journal-article" @default.
- W3215677538 hasAuthorship W3215677538A5004476106 @default.
- W3215677538 hasBestOaLocation W32156775381 @default.
- W3215677538 hasConcept C105702510 @default.
- W3215677538 hasConcept C126322002 @default.
- W3215677538 hasConcept C126838900 @default.
- W3215677538 hasConcept C141071460 @default.
- W3215677538 hasConcept C142724271 @default.
- W3215677538 hasConcept C146957229 @default.
- W3215677538 hasConcept C171089720 @default.
- W3215677538 hasConcept C2776204877 @default.
- W3215677538 hasConcept C2779018429 @default.
- W3215677538 hasConcept C2779400597 @default.
- W3215677538 hasConcept C2781172350 @default.
- W3215677538 hasConcept C42219234 @default.
- W3215677538 hasConcept C46762472 @default.
- W3215677538 hasConcept C503630168 @default.
- W3215677538 hasConcept C541997718 @default.
- W3215677538 hasConcept C71924100 @default.
- W3215677538 hasConceptScore W3215677538C105702510 @default.
- W3215677538 hasConceptScore W3215677538C126322002 @default.
- W3215677538 hasConceptScore W3215677538C126838900 @default.
- W3215677538 hasConceptScore W3215677538C141071460 @default.
- W3215677538 hasConceptScore W3215677538C142724271 @default.
- W3215677538 hasConceptScore W3215677538C146957229 @default.
- W3215677538 hasConceptScore W3215677538C171089720 @default.
- W3215677538 hasConceptScore W3215677538C2776204877 @default.
- W3215677538 hasConceptScore W3215677538C2779018429 @default.
- W3215677538 hasConceptScore W3215677538C2779400597 @default.
- W3215677538 hasConceptScore W3215677538C2781172350 @default.
- W3215677538 hasConceptScore W3215677538C42219234 @default.
- W3215677538 hasConceptScore W3215677538C46762472 @default.
- W3215677538 hasConceptScore W3215677538C503630168 @default.
- W3215677538 hasConceptScore W3215677538C541997718 @default.
- W3215677538 hasConceptScore W3215677538C71924100 @default.
- W3215677538 hasIssue "2(109)" @default.
- W3215677538 hasLocation W32156775381 @default.
- W3215677538 hasOpenAccess W3215677538 @default.
- W3215677538 hasPrimaryLocation W32156775381 @default.
- W3215677538 hasRelatedWork W142403880 @default.
- W3215677538 hasRelatedWork W2026554160 @default.
- W3215677538 hasRelatedWork W2033479047 @default.
- W3215677538 hasRelatedWork W2050118449 @default.
- W3215677538 hasRelatedWork W2060539584 @default.
- W3215677538 hasRelatedWork W2071053625 @default.
- W3215677538 hasRelatedWork W2110028213 @default.
- W3215677538 hasRelatedWork W2412441875 @default.
- W3215677538 hasRelatedWork W2593058100 @default.
- W3215677538 hasRelatedWork W3009900761 @default.
- W3215677538 isParatext "false" @default.
- W3215677538 isRetracted "false" @default.
- W3215677538 magId "3215677538" @default.
- W3215677538 workType "article" @default.