Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215692945> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W3215692945 abstract "The immune system of all jawed vertebrates is composed of two major subsystems, the innate (non-specific) and adaptive (specific) immune system. The innate immune system is the first to respond to infectious agents; however, it does not provide longlasting protection. The adaptive immune system is activated later and responds to pathogens with specificity and memory. The main components of the adaptive immune system, including T cell receptors (TCRs), major histocompatibility complex (MHC), immunoglobulins (Igs), and recombination-activating gene (RAG) arose in the first jawed fish (cartilaginous and teleost fish). This review explores and discusses components of the adaptive immune system in teleost fish and recent developments in comparative immunology. Similar to mammals, the adaptive immune system in teleost fish is divided into two components: cellular-mediated responses and humoralmediated responses. T cells, the principal elements of cellular-mediated adaptive immune responses, differentiate into effector helper T (Th) cells or effector cytotoxic T cells (CTLs). The central elements involved in the differentiation of Th subsets in mammals, cytokines and master transcription factors, have also been identified in teleost fish. In addition, each subset of Th cells, defined with a particular cytokine to control the immune responses, has been described in teleost fish. Similarly, to mammals, CTLs contribute to cellular cytotoxicity in teleost fish. B cells act as a central player in humoral-mediated adaptive immunity by producing opsonizing, neutralizing and complement-binding antibodies and inducing antibody-dependent cellular cytotoxicity (ADCC). Three classes of antibodies named IgM, IgD, and IgT/Z have been characterized in teleost fish. The presence of an adaptive immune system and consequent immune memory in teleost fish allows vaccination, the most appropriate method for disease control in aquaculture. Immunological studies in fish provide a comprehensive assessment of the fish immune system, which is crucial for understanding the evolution of the mammalian immune system." @default.
- W3215692945 created "2021-12-06" @default.
- W3215692945 creator A5020336265 @default.
- W3215692945 creator A5053283242 @default.
- W3215692945 creator A5077494683 @default.
- W3215692945 date "2021-11-25" @default.
- W3215692945 modified "2023-10-16" @default.
- W3215692945 title "Adaptive Immune System in Fish" @default.
- W3215692945 doi "https://doi.org/10.4194/trjfas20235" @default.
- W3215692945 hasPublicationYear "2021" @default.
- W3215692945 type Work @default.
- W3215692945 sameAs 3215692945 @default.
- W3215692945 citedByCount "1" @default.
- W3215692945 countsByYear W32156929452023 @default.
- W3215692945 crossrefType "journal-article" @default.
- W3215692945 hasAuthorship W3215692945A5020336265 @default.
- W3215692945 hasAuthorship W3215692945A5053283242 @default.
- W3215692945 hasAuthorship W3215692945A5077494683 @default.
- W3215692945 hasBestOaLocation W32156929451 @default.
- W3215692945 hasConcept C136449434 @default.
- W3215692945 hasConcept C154317977 @default.
- W3215692945 hasConcept C159654299 @default.
- W3215692945 hasConcept C193419808 @default.
- W3215692945 hasConcept C202751555 @default.
- W3215692945 hasConcept C203014093 @default.
- W3215692945 hasConcept C207936829 @default.
- W3215692945 hasConcept C2779341262 @default.
- W3215692945 hasConcept C40677261 @default.
- W3215692945 hasConcept C51785407 @default.
- W3215692945 hasConcept C542903549 @default.
- W3215692945 hasConcept C54355233 @default.
- W3215692945 hasConcept C86803240 @default.
- W3215692945 hasConcept C8891405 @default.
- W3215692945 hasConcept C95444343 @default.
- W3215692945 hasConceptScore W3215692945C136449434 @default.
- W3215692945 hasConceptScore W3215692945C154317977 @default.
- W3215692945 hasConceptScore W3215692945C159654299 @default.
- W3215692945 hasConceptScore W3215692945C193419808 @default.
- W3215692945 hasConceptScore W3215692945C202751555 @default.
- W3215692945 hasConceptScore W3215692945C203014093 @default.
- W3215692945 hasConceptScore W3215692945C207936829 @default.
- W3215692945 hasConceptScore W3215692945C2779341262 @default.
- W3215692945 hasConceptScore W3215692945C40677261 @default.
- W3215692945 hasConceptScore W3215692945C51785407 @default.
- W3215692945 hasConceptScore W3215692945C542903549 @default.
- W3215692945 hasConceptScore W3215692945C54355233 @default.
- W3215692945 hasConceptScore W3215692945C86803240 @default.
- W3215692945 hasConceptScore W3215692945C8891405 @default.
- W3215692945 hasConceptScore W3215692945C95444343 @default.
- W3215692945 hasIssue "4" @default.
- W3215692945 hasLocation W32156929451 @default.
- W3215692945 hasOpenAccess W3215692945 @default.
- W3215692945 hasPrimaryLocation W32156929451 @default.
- W3215692945 hasRelatedWork W1574628415 @default.
- W3215692945 hasRelatedWork W1975418102 @default.
- W3215692945 hasRelatedWork W1985361111 @default.
- W3215692945 hasRelatedWork W2103515427 @default.
- W3215692945 hasRelatedWork W2141330728 @default.
- W3215692945 hasRelatedWork W2188294308 @default.
- W3215692945 hasRelatedWork W2223869382 @default.
- W3215692945 hasRelatedWork W2610389334 @default.
- W3215692945 hasRelatedWork W2946615038 @default.
- W3215692945 hasRelatedWork W3209390153 @default.
- W3215692945 hasVolume "22" @default.
- W3215692945 isParatext "false" @default.
- W3215692945 isRetracted "false" @default.
- W3215692945 magId "3215692945" @default.
- W3215692945 workType "article" @default.