FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215697821> ?p ?o ?g. }

• W3215697821 abstract "The cognitive impairment pattern of deficit schizophrenia (DS) is centered on an impaired attention function. Previous studies have suggested that the exploratory eye movement (EEM) tests reflect attention deficits in patients with schizophrenia. However, no study has investigated the characteristics of eye movement in DS in the Chinese Han population. This study aimed to investigate the pattern of eye movement characteristics in DS patients and to examine whether eye movement characteristic is associated with serious negative symptoms and cognitive decline in this schizophrenia subtype.A total of 86 male patients [37 DS and 49 non-deficit schizophrenia (NDS)] and 80 healthy controls (HC) participated in this study. Clinical symptoms were assessed using the Scale for the Assessment of Positive Symptoms (SAPS) and Scale for the Assessment of Negative Symptoms (SANS). Cognitive function was assessed using the Mattis Dementia Rating Scale (MDRS-2). Eye movement data of subjects were collected using an eye movement tracking analyzer.There were significant differences in the overall eye movement data and cognitive test scores among the three groups (all P < 0.001). Both DS and NDS schizophrenia subgroups showed more severe eye movement and cognitive impairment compared with the control group. The number of eye fixations (NEF), total of eye scanning length (TESL), and cognitive function in DS patients were significantly lower than those in NDS patients. The discriminant analysis (D score) was higher than that of the control group (P < 0.001). In the DS group, the inattention factor of SANS was negatively correlated with the attention factor (r = - 0.545, P = 0.001) and structure factor of cognitive (r = - 0.389, P = 0.023), the affective flattening factor of SANS was negatively correlated with TESL (r = - 0.353, P = 0.041) and initiation/retention factor of cognitive (r = - 0.376,P = 0.028). TESL was found to positively correlate with the MDRS-2 total score (r = 0.427, P = 0.012), attention factor (r = 0.354, P = 0.040), and memory factor (r = 0.349, P = 0.043) in the DS group, whereas the mean of eye scanning length (MESL) positively correlated with cognitive impairments in the NDS group. The negative symptoms showed no significant correlation with cognition in the NDS group.Total of eye scanning length may be a characteristic eye movement symptom in DS patients, which is associated with serious negative symptoms and cognitive impairment in this schizophrenia subtype." @default.
• W3215697821 created "2021-12-06" @default.
• W3215697821 creator A5021541475 @default.
• W3215697821 creator A5029367666 @default.
• W3215697821 creator A5036232375 @default.
• W3215697821 creator A5041107856 @default.
• W3215697821 creator A5045591391 @default.
• W3215697821 creator A5049776440 @default.
• W3215697821 creator A5073627302 @default.
• W3215697821 creator A5082894850 @default.
• W3215697821 date "2021-11-24" @default.
• W3215697821 modified "2023-09-28" @default.
• W3215697821 title "Eye movement characteristics in male patients with deficit and non-deficit schizophrenia and their relationships with psychiatric symptoms and cognitive function" @default.
• W3215697821 cites W1566810616 @default.
• W3215697821 cites W1572489670 @default.
• W3215697821 cites W1694864989 @default.
• W3215697821 cites W1763821615 @default.
• W3215697821 cites W1811162218 @default.
• W3215697821 cites W1926063538 @default.
• W3215697821 cites W1963497698 @default.
• W3215697821 cites W1965455400 @default.
• W3215697821 cites W1966561318 @default.
• W3215697821 cites W1975566892 @default.
• W3215697821 cites W1976392913 @default.
• W3215697821 cites W1984564133 @default.
• W3215697821 cites W1987074340 @default.
• W3215697821 cites W1989222694 @default.
• W3215697821 cites W1997176378 @default.
• W3215697821 cites W2003366144 @default.
• W3215697821 cites W2005498978 @default.
• W3215697821 cites W2006694409 @default.
• W3215697821 cites W2010407531 @default.
• W3215697821 cites W2010654188 @default.
• W3215697821 cites W2011318319 @default.
• W3215697821 cites W2011491747 @default.
• W3215697821 cites W2014678580 @default.
• W3215697821 cites W2015515732 @default.
• W3215697821 cites W2017579904 @default.
• W3215697821 cites W2017627306 @default.
• W3215697821 cites W2027840174 @default.
• W3215697821 cites W2029548948 @default.
• W3215697821 cites W2032453962 @default.
• W3215697821 cites W2035528776 @default.
• W3215697821 cites W2038230628 @default.
• W3215697821 cites W2047131549 @default.
• W3215697821 cites W2048241166 @default.
• W3215697821 cites W2050764161 @default.
• W3215697821 cites W2057931553 @default.
• W3215697821 cites W2062897543 @default.
• W3215697821 cites W2068702172 @default.
• W3215697821 cites W2078107161 @default.
• W3215697821 cites W2086624926 @default.
• W3215697821 cites W2086830880 @default.
• W3215697821 cites W2093867364 @default.
• W3215697821 cites W2094923233 @default.
• W3215697821 cites W2096922156 @default.
• W3215697821 cites W2098594608 @default.
• W3215697821 cites W2102048758 @default.
• W3215697821 cites W2102303216 @default.
• W3215697821 cites W2105378541 @default.
• W3215697821 cites W2111347270 @default.
• W3215697821 cites W2115557676 @default.
• W3215697821 cites W2117530105 @default.
• W3215697821 cites W2119187334 @default.
• W3215697821 cites W2126338481 @default.
• W3215697821 cites W2131437070 @default.
• W3215697821 cites W2135042605 @default.
• W3215697821 cites W2139078690 @default.
• W3215697821 cites W2141766296 @default.
• W3215697821 cites W2142562647 @default.
• W3215697821 cites W2142807256 @default.
• W3215697821 cites W2145920801 @default.
• W3215697821 cites W2148600530 @default.
• W3215697821 cites W2152397291 @default.
• W3215697821 cites W2153914645 @default.
• W3215697821 cites W2154165853 @default.
• W3215697821 cites W2155846146 @default.
• W3215697821 cites W2156601000 @default.
• W3215697821 cites W2157786991 @default.
• W3215697821 cites W2160563460 @default.
• W3215697821 cites W2163058355 @default.
• W3215697821 cites W2163486360 @default.
• W3215697821 cites W2170603069 @default.
• W3215697821 cites W2177304787 @default.
• W3215697821 cites W2215088909 @default.
• W3215697821 cites W2260550725 @default.
• W3215697821 cites W2271696488 @default.
• W3215697821 cites W2285221939 @default.
• W3215697821 cites W2521208805 @default.
• W3215697821 cites W2527733746 @default.
• W3215697821 cites W2611230952 @default.
• W3215697821 cites W2751884637 @default.
• W3215697821 cites W2752885036 @default.
• W3215697821 cites W2801704870 @default.
• W3215697821 cites W2884206170 @default.
• W3215697821 cites W2945070191 @default.
• W3215697821 cites W2968838584 @default.
• W3215697821 cites W2991821479 @default.
• W3215697821 doi "https://doi.org/10.1186/s12868-021-00673-w" @default.
• W3215697821 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8613938" @default.

• next