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• W3215706494 abstract "Replacement of a U in an RNA duplex with a pseudouridine (Ψ), in general, stabilize the duplex because of the stronger stacking interaction, even concerning the wobble pair with G. The tRNA species specific to the AUA isoleucine codon in many eukaryotes have a Ψ at the first position of the anticodon. This tRNAIle would cause mistranslation if it could recognize the AUG codon through formation of a Ψ-G base pair. Here, I propose rationales for the minimal promotive effect of the U to Ψ modification on the mistranslation of the AUG codon." @default.
• W3215706494 created "2021-12-06" @default.
• W3215706494 creator A5085701117 @default.
• W3215706494 date "2021-12-02" @default.
• W3215706494 modified "2023-09-27" @default.
• W3215706494 title "The uridine to pseudouridine modification at the wobble position of eukaryotic isoleucine tRNA species is unlikely to induce mistranslation" @default.
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• W3215706494 doi "https://doi.org/10.1080/15257770.2021.2011916" @default.
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