Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215735269> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3215735269 endingPage "387" @default.
- W3215735269 startingPage "383" @default.
- W3215735269 abstract "Vulvovaginal atrophy is frequent, can be bothersome and can impair quality of life in postmenopausal women. The main objective of this prospective, randomized study was to compare the acceptability of low-dose vaginal 17β-estradiol (estradiol) tablets and vaginal promestriene cream in postmenopausal women with moderate-to-severe symptomatic vulvovaginal atrophy.Overall, 120 patients were randomized to receive estradiol or promestriene (n = 60 per group). Acceptability was assessed with a specific questionnaire. Symptom intensity, the Vaginal Health Index (VHI), vaginal pH and the Vaginal Maturation Index were also evaluated.Acceptability was higher for estradiol tablets. Compared to promestriene cream, hygiene and ease of use were greater after 4 weeks (p = 0.011 and p = 0.001, respectively) and after 12 weeks (p = 0.009 and p = 0.011, respectively). Reduction of symptom intensity was greater with estradiol. Both treatments improved the VHI and decreased vaginal pH. However, superficial cell percentages increased significantly (p < 0.001) with estradiol but not with promestriene (p = 0.241), with a statistically significant difference between means (p = 0.004).Our results support the use of vaginal low-dose estradiol tablets as compared to vaginal promestriene cream for the management of moderate-to-severe symptomatic vulvovaginal atrophy in postmenopausal women.NCT04232813." @default.
- W3215735269 created "2021-12-06" @default.
- W3215735269 creator A5020075538 @default.
- W3215735269 creator A5059241116 @default.
- W3215735269 creator A5068621774 @default.
- W3215735269 date "2021-11-23" @default.
- W3215735269 modified "2023-09-27" @default.
- W3215735269 title "Efficacy of low-dose vaginal 17β-estradiol versus vaginal promestriene for vulvovaginal atrophy" @default.
- W3215735269 cites W1700139069 @default.
- W3215735269 cites W1978948448 @default.
- W3215735269 cites W1979932673 @default.
- W3215735269 cites W1989614355 @default.
- W3215735269 cites W2031061007 @default.
- W3215735269 cites W2056926300 @default.
- W3215735269 cites W2066063023 @default.
- W3215735269 cites W2075460812 @default.
- W3215735269 cites W2082945545 @default.
- W3215735269 cites W2130060147 @default.
- W3215735269 cites W2236105400 @default.
- W3215735269 cites W2767582690 @default.
- W3215735269 cites W2790884484 @default.
- W3215735269 cites W2794063291 @default.
- W3215735269 cites W2794301989 @default.
- W3215735269 cites W2965274941 @default.
- W3215735269 cites W3006756650 @default.
- W3215735269 cites W3132524431 @default.
- W3215735269 cites W3138215196 @default.
- W3215735269 cites W3156262496 @default.
- W3215735269 cites W4211120499 @default.
- W3215735269 cites W4231375072 @default.
- W3215735269 cites W4244526763 @default.
- W3215735269 doi "https://doi.org/10.1080/13697137.2021.1998436" @default.
- W3215735269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34813408" @default.
- W3215735269 hasPublicationYear "2021" @default.
- W3215735269 type Work @default.
- W3215735269 sameAs 3215735269 @default.
- W3215735269 citedByCount "3" @default.
- W3215735269 countsByYear W32157352692023 @default.
- W3215735269 crossrefType "journal-article" @default.
- W3215735269 hasAuthorship W3215735269A5020075538 @default.
- W3215735269 hasAuthorship W3215735269A5059241116 @default.
- W3215735269 hasAuthorship W3215735269A5068621774 @default.
- W3215735269 hasConcept C126322002 @default.
- W3215735269 hasConcept C126894567 @default.
- W3215735269 hasConcept C141071460 @default.
- W3215735269 hasConcept C168563851 @default.
- W3215735269 hasConcept C2776917545 @default.
- W3215735269 hasConcept C2777744392 @default.
- W3215735269 hasConcept C2781172350 @default.
- W3215735269 hasConcept C29456083 @default.
- W3215735269 hasConcept C3018603563 @default.
- W3215735269 hasConcept C71924100 @default.
- W3215735269 hasConceptScore W3215735269C126322002 @default.
- W3215735269 hasConceptScore W3215735269C126894567 @default.
- W3215735269 hasConceptScore W3215735269C141071460 @default.
- W3215735269 hasConceptScore W3215735269C168563851 @default.
- W3215735269 hasConceptScore W3215735269C2776917545 @default.
- W3215735269 hasConceptScore W3215735269C2777744392 @default.
- W3215735269 hasConceptScore W3215735269C2781172350 @default.
- W3215735269 hasConceptScore W3215735269C29456083 @default.
- W3215735269 hasConceptScore W3215735269C3018603563 @default.
- W3215735269 hasConceptScore W3215735269C71924100 @default.
- W3215735269 hasIssue "4" @default.
- W3215735269 hasLocation W32157352691 @default.
- W3215735269 hasLocation W32157352692 @default.
- W3215735269 hasOpenAccess W3215735269 @default.
- W3215735269 hasPrimaryLocation W32157352691 @default.
- W3215735269 hasRelatedWork W1979932673 @default.
- W3215735269 hasRelatedWork W2066691329 @default.
- W3215735269 hasRelatedWork W2099018262 @default.
- W3215735269 hasRelatedWork W2411950246 @default.
- W3215735269 hasRelatedWork W2573952960 @default.
- W3215735269 hasRelatedWork W2889906376 @default.
- W3215735269 hasRelatedWork W2919676902 @default.
- W3215735269 hasRelatedWork W2940534731 @default.
- W3215735269 hasRelatedWork W3020207203 @default.
- W3215735269 hasRelatedWork W4361225584 @default.
- W3215735269 hasVolume "25" @default.
- W3215735269 isParatext "false" @default.
- W3215735269 isRetracted "false" @default.
- W3215735269 magId "3215735269" @default.
- W3215735269 workType "article" @default.