Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215736354> ?p ?o ?g. }
- W3215736354 endingPage "12994" @default.
- W3215736354 startingPage "12994" @default.
- W3215736354 abstract "There is a lack of knowledge regarding the connection between the ocular and nasal epithelia. This narrative review focuses on conjunctival, corneal, ultrastructural corneal stroma, and nasal epithelia as well as an introduction into their interconnections. We describe in detail the morphology and physiology of the ocular surface, the nasolacrimal ducts, and the nasal cavity. This knowledge provides a basis for functional studies and the development of relevant cell culture models that can be used to investigate the pathogenesis of diseases related to these complex structures. Moreover, we also provide a state-of-the-art overview regarding the development of 3D culture models, which allow for addressing research questions in models resembling the in vivo situation. In particular, we give an overview of the current developments of corneal 3D and organoid models, as well as 3D cell culture models of epithelia with goblet cells (conjunctiva and nasal cavity). The benefits and shortcomings of these cell culture models are discussed. As examples for pathogens related to ocular and nasal epithelia, we discuss infections caused by adenovirus and measles virus. In addition to pathogens, also external triggers such as allergens can cause rhinoconjunctivitis. These diseases exemplify the interconnections between the ocular surface and nasal epithelia in a molecular and clinical context. With a final translational section on optical coherence tomography (OCT), we provide an overview about the applicability of this technique in basic research and clinical ophthalmology. The techniques presented herein will be instrumental in further elucidating the functional interrelations and crosstalk between ocular and nasal epithelia." @default.
- W3215736354 created "2021-12-06" @default.
- W3215736354 creator A5014419906 @default.
- W3215736354 creator A5021970972 @default.
- W3215736354 creator A5025413690 @default.
- W3215736354 creator A5038523891 @default.
- W3215736354 creator A5046622297 @default.
- W3215736354 creator A5048614702 @default.
- W3215736354 creator A5050832985 @default.
- W3215736354 creator A5076607475 @default.
- W3215736354 creator A5079388018 @default.
- W3215736354 date "2021-11-30" @default.
- W3215736354 modified "2023-09-25" @default.
- W3215736354 title "The Communication between Ocular Surface and Nasal Epithelia in 3D Cell Culture Technology for Translational Research: A Narrative Review" @default.
- W3215736354 cites W10254197 @default.
- W3215736354 cites W110209143 @default.
- W3215736354 cites W1489062892 @default.
- W3215736354 cites W1489818823 @default.
- W3215736354 cites W1511739548 @default.
- W3215736354 cites W1532699570 @default.
- W3215736354 cites W1537855055 @default.
- W3215736354 cites W1541095084 @default.
- W3215736354 cites W1567692140 @default.
- W3215736354 cites W1589352563 @default.
- W3215736354 cites W1709164896 @default.
- W3215736354 cites W1851050658 @default.
- W3215736354 cites W1852738787 @default.
- W3215736354 cites W1924842828 @default.
- W3215736354 cites W1954007937 @default.
- W3215736354 cites W1966550578 @default.
- W3215736354 cites W1971333614 @default.
- W3215736354 cites W1971765707 @default.
- W3215736354 cites W1972221292 @default.
- W3215736354 cites W1973755752 @default.
- W3215736354 cites W1974832336 @default.
- W3215736354 cites W1976845238 @default.
- W3215736354 cites W1976868395 @default.
- W3215736354 cites W1978582812 @default.
- W3215736354 cites W1981267240 @default.
- W3215736354 cites W1982112785 @default.
- W3215736354 cites W1982712041 @default.
- W3215736354 cites W1983585074 @default.
- W3215736354 cites W1983756548 @default.
- W3215736354 cites W1984114278 @default.
- W3215736354 cites W1986551205 @default.
- W3215736354 cites W1992542482 @default.
- W3215736354 cites W2003589970 @default.
- W3215736354 cites W2004405596 @default.
- W3215736354 cites W2008855802 @default.
- W3215736354 cites W2010327845 @default.
- W3215736354 cites W2018963982 @default.
- W3215736354 cites W2027145049 @default.
- W3215736354 cites W2027746633 @default.
- W3215736354 cites W2028062688 @default.
- W3215736354 cites W2030589581 @default.
- W3215736354 cites W2033726575 @default.
- W3215736354 cites W2034187812 @default.
- W3215736354 cites W2035350115 @default.
- W3215736354 cites W2036895638 @default.
- W3215736354 cites W2037261076 @default.
- W3215736354 cites W2040206301 @default.
- W3215736354 cites W2043243996 @default.
- W3215736354 cites W2044928246 @default.
- W3215736354 cites W2045191671 @default.
- W3215736354 cites W2049540404 @default.
- W3215736354 cites W2051758487 @default.
- W3215736354 cites W2057892077 @default.
- W3215736354 cites W2059585997 @default.
- W3215736354 cites W2063004548 @default.
- W3215736354 cites W2063522847 @default.
- W3215736354 cites W2064934848 @default.
- W3215736354 cites W2071032594 @default.
- W3215736354 cites W2071272210 @default.
- W3215736354 cites W2082624887 @default.
- W3215736354 cites W2088793000 @default.
- W3215736354 cites W2089627224 @default.
- W3215736354 cites W2090046540 @default.
- W3215736354 cites W2092514419 @default.
- W3215736354 cites W2094928044 @default.
- W3215736354 cites W2095375452 @default.
- W3215736354 cites W2097378210 @default.
- W3215736354 cites W2100684184 @default.
- W3215736354 cites W2100890700 @default.
- W3215736354 cites W2101594367 @default.
- W3215736354 cites W2112515459 @default.
- W3215736354 cites W2116175479 @default.
- W3215736354 cites W2120793327 @default.
- W3215736354 cites W2126917358 @default.
- W3215736354 cites W2133868521 @default.
- W3215736354 cites W2136015927 @default.
- W3215736354 cites W2139211367 @default.
- W3215736354 cites W2145816564 @default.
- W3215736354 cites W2148285949 @default.
- W3215736354 cites W2148655151 @default.
- W3215736354 cites W2150380586 @default.
- W3215736354 cites W2151542897 @default.
- W3215736354 cites W2159607494 @default.
- W3215736354 cites W2159646953 @default.