Matches in SemOpenAlex for { <https://semopenalex.org/work/W3215968606> ?p ?o ?g. }
- W3215968606 endingPage "1259" @default.
- W3215968606 startingPage "1254" @default.
- W3215968606 abstract "An algorithm was designed aiming to provide consistency of pancreatic enzyme replacement therapy (PERT) dosing/titration across healthcare professionals in pancreaticobiliary cancers (PBCs). This prospective observational study aimed to validate this algorithm.Consecutive patients with inoperable or postoperative PBC with pancreatic exocrine insufficiency (PEI) symptoms, not taking PERT, or taking below the algorithm starting dose, were eligible. A dietitian or clinical nurse specialist reviewed patients for up to 3 weeks, titrating PERT as per the algorithm. Feasibility of algorithm deliverability was assessed by the percentage of patients with successful completion (primary objective).Twenty-five patients were eligible (N = 25): at baseline, 22 took PERT (100% on suboptimal doses, 54.5% taking incorrectly) and 3 initiated PERT because of PEI symptoms. Algorithm completion (20 of 25, 80%) confirming deliverability by dietitians (11 of 12, 92%) and clinical nurse specialists (9 of 13, 69%). Symptom resolution occurred in 8 of 19 (42%), 3 of 7 (43%), and 1 of 3 (33%) patients at first, second, and third reviews, respectively; advice compliance was between 63% and 86%.This algorithm provides a structured method to titrate PERT. At diagnosis, all patients with PBC should be assessed for PEI and adequate PERT initiated. Regular reviews are required for timely symptom resolution and adequate escalation, facilitating differential diagnosis if refractory symptoms exist." @default.
- W3215968606 created "2021-12-06" @default.
- W3215968606 creator A5034499293 @default.
- W3215968606 creator A5041768679 @default.
- W3215968606 creator A5042493679 @default.
- W3215968606 creator A5058517511 @default.
- W3215968606 creator A5067094887 @default.
- W3215968606 creator A5067588077 @default.
- W3215968606 creator A5075059160 @default.
- W3215968606 creator A5076171187 @default.
- W3215968606 creator A5077826150 @default.
- W3215968606 creator A5083714885 @default.
- W3215968606 creator A5083842007 @default.
- W3215968606 creator A5087850177 @default.
- W3215968606 date "2021-10-01" @default.
- W3215968606 modified "2023-09-30" @default.
- W3215968606 title "Pancreatic Enzyme Replacement Therapy for Patients Diagnosed With Pancreaticobiliary Cancer" @default.
- W3215968606 cites W2039225116 @default.
- W3215968606 cites W2113165406 @default.
- W3215968606 cites W2140252679 @default.
- W3215968606 cites W2161509070 @default.
- W3215968606 cites W2167565084 @default.
- W3215968606 cites W2341052126 @default.
- W3215968606 cites W2527118921 @default.
- W3215968606 cites W2577520851 @default.
- W3215968606 cites W2762928883 @default.
- W3215968606 cites W2884362756 @default.
- W3215968606 cites W2898414515 @default.
- W3215968606 cites W2898561267 @default.
- W3215968606 cites W2908183275 @default.
- W3215968606 cites W2947916602 @default.
- W3215968606 cites W2967052593 @default.
- W3215968606 cites W3001631032 @default.
- W3215968606 cites W3014396092 @default.
- W3215968606 cites W814239660 @default.
- W3215968606 doi "https://doi.org/10.1097/mpa.0000000000001906" @default.
- W3215968606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34860808" @default.
- W3215968606 hasPublicationYear "2021" @default.
- W3215968606 type Work @default.
- W3215968606 sameAs 3215968606 @default.
- W3215968606 citedByCount "3" @default.
- W3215968606 countsByYear W32159686062022 @default.
- W3215968606 countsByYear W32159686062023 @default.
- W3215968606 crossrefType "journal-article" @default.
- W3215968606 hasAuthorship W3215968606A5034499293 @default.
- W3215968606 hasAuthorship W3215968606A5041768679 @default.
- W3215968606 hasAuthorship W3215968606A5042493679 @default.
- W3215968606 hasAuthorship W3215968606A5058517511 @default.
- W3215968606 hasAuthorship W3215968606A5067094887 @default.
- W3215968606 hasAuthorship W3215968606A5067588077 @default.
- W3215968606 hasAuthorship W3215968606A5075059160 @default.
- W3215968606 hasAuthorship W3215968606A5076171187 @default.
- W3215968606 hasAuthorship W3215968606A5077826150 @default.
- W3215968606 hasAuthorship W3215968606A5083714885 @default.
- W3215968606 hasAuthorship W3215968606A5083842007 @default.
- W3215968606 hasAuthorship W3215968606A5087850177 @default.
- W3215968606 hasBestOaLocation W32159686062 @default.
- W3215968606 hasConcept C11413529 @default.
- W3215968606 hasConcept C121608353 @default.
- W3215968606 hasConcept C126322002 @default.
- W3215968606 hasConcept C188816634 @default.
- W3215968606 hasConcept C23131810 @default.
- W3215968606 hasConcept C2777288759 @default.
- W3215968606 hasConcept C2778764654 @default.
- W3215968606 hasConcept C2780210213 @default.
- W3215968606 hasConcept C3019860435 @default.
- W3215968606 hasConcept C41008148 @default.
- W3215968606 hasConcept C71924100 @default.
- W3215968606 hasConceptScore W3215968606C11413529 @default.
- W3215968606 hasConceptScore W3215968606C121608353 @default.
- W3215968606 hasConceptScore W3215968606C126322002 @default.
- W3215968606 hasConceptScore W3215968606C188816634 @default.
- W3215968606 hasConceptScore W3215968606C23131810 @default.
- W3215968606 hasConceptScore W3215968606C2777288759 @default.
- W3215968606 hasConceptScore W3215968606C2778764654 @default.
- W3215968606 hasConceptScore W3215968606C2780210213 @default.
- W3215968606 hasConceptScore W3215968606C3019860435 @default.
- W3215968606 hasConceptScore W3215968606C41008148 @default.
- W3215968606 hasConceptScore W3215968606C71924100 @default.
- W3215968606 hasIssue "9" @default.
- W3215968606 hasLocation W32159686061 @default.
- W3215968606 hasLocation W32159686062 @default.
- W3215968606 hasLocation W32159686063 @default.
- W3215968606 hasLocation W32159686064 @default.
- W3215968606 hasOpenAccess W3215968606 @default.
- W3215968606 hasPrimaryLocation W32159686061 @default.
- W3215968606 hasRelatedWork W2056104331 @default.
- W3215968606 hasRelatedWork W2295722933 @default.
- W3215968606 hasRelatedWork W2406430468 @default.
- W3215968606 hasRelatedWork W2531350361 @default.
- W3215968606 hasRelatedWork W2765980456 @default.
- W3215968606 hasRelatedWork W2801204836 @default.
- W3215968606 hasRelatedWork W2947337648 @default.
- W3215968606 hasRelatedWork W2976382042 @default.
- W3215968606 hasRelatedWork W4280605750 @default.
- W3215968606 hasRelatedWork W4309658777 @default.
- W3215968606 hasVolume "50" @default.
- W3215968606 isParatext "false" @default.