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- W3216063762 abstract "The creativity impairment under acute stress may be closely related to the down-regulation of the prefrontal cortex function caused by stress-related neurotransmitters and hormones. In the current study, we explored whether transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) eliminated stress-induced creativity impairment and the potential mechanism from the perspective of stress response recovery. Seventy participants were randomly allocated to a group undergoing the activation of right DLPFC and the deactivation of left DLPFC (R+L-; N = 35), and a group of sham stimulation (sham; N = 35). Participants received tDCS after the stress induction, and then completed the Alternative Uses Task (AUT) and the Remote Association Task (RAT) during the stimulation. The stress response was indicated using heart rate, cortisol, and emotion changes. Results showed that R+L- stimulation facilitated the recovery of anxious state compared to sham stimulation. We also found that the decreased value of AUT scores after stress in the R+L- group was significantly lower than that in the sham group. Moreover, further analysis revealed state anxiety mediated the effect of tDCS on the flexibility component of the AUT. We concluded that bilateral tDCS over the DLPFC is efficient in alleviating stress-induced creativity impairment, which may correlate with greater recovery of state anxiety. Our findings provide causal evidence for the neurophysiological mechanisms by which stress affects creativity, as well as clinical suggestions for stress-related psychiatric disorders prevention and intervention." @default.
- W3216063762 created "2021-12-06" @default.
- W3216063762 creator A5011092893 @default.
- W3216063762 creator A5023997691 @default.
- W3216063762 creator A5024120345 @default.
- W3216063762 creator A5043777472 @default.
- W3216063762 creator A5050419964 @default.
- W3216063762 creator A5054096696 @default.
- W3216063762 creator A5077020613 @default.
- W3216063762 creator A5086615897 @default.
- W3216063762 date "2022-01-01" @default.
- W3216063762 modified "2023-09-25" @default.
- W3216063762 title "Transcranial direct current stimulation of bilateral dorsolateral prefrontal cortex eliminates creativity impairment induced by acute stress" @default.
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