FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216188636> ?p ?o ?g. }

• W3216188636 endingPage "10" @default.
• W3216188636 startingPage "1" @default.
• W3216188636 abstract "Alterations of brain functional connectivity in patients with type 2 diabetes mellitus (T2DM) have been reported by resting-state functional magnetic resonance imaging studies, but the underlying precise neuropathological mechanism remains unclear. This study is aimed at investigating the implicit alterations of functional connections in T2DM by integrating functional connectivity strength (FCS) and Granger causality analysis (GCA) and further exploring their associations with clinical characteristics. Sixty T2DM patients and thirty-three sex-, age-, and education-matched healthy controls (HC) were recruited. Global FCS analysis of resting-state functional magnetic resonance imaging was performed to explore seed regions with significant differences between the two groups; then, GCA was applied to detect directional effective connectivity (EC) between the seeds and other brain regions. Correlations of EC with clinical variables were further explored in T2DM patients. Compared with HC, T2DM patients showed lower FCS in the bilateral fusiform gyrus, right superior frontal gyrus (SFG), and right postcentral gyrus, but higher FCS in the right supplementary motor area (SMA). Moreover, altered directional EC was found between the left fusiform gyrus and bilateral lingual gyrus and right medial frontal gyrus (MFG), as well as between the right SFG and bilateral frontal regions. In addition, triglyceride, insulin, and plasma glucose levels were correlated with the abnormal EC of the left fusiform, while disease duration and cognitive function were associated with the abnormal EC of the right SFG in T2DM patients. These results suggest that T2DM patients show aberrant brain function connectivity strength and effective connectivity which is associated with the diabetes-related metabolic characteristics, disease duration, and cognitive function, providing further insights into the complex neural basis of diabetes." @default.
• W3216188636 created "2021-12-06" @default.
• W3216188636 creator A5026996727 @default.
• W3216188636 creator A5029751699 @default.
• W3216188636 creator A5030691366 @default.
• W3216188636 creator A5031303595 @default.
• W3216188636 creator A5031466356 @default.
• W3216188636 creator A5054449543 @default.
• W3216188636 creator A5069849278 @default.
• W3216188636 creator A5073830471 @default.
• W3216188636 creator A5091904163 @default.
• W3216188636 date "2021-11-28" @default.
• W3216188636 modified "2023-10-15" @default.
• W3216188636 title "Aberrant Brain Functional Connectivity Strength and Effective Connectivity in Patients with Type 2 Diabetes Mellitus" @default.
• W3216188636 cites W1528193995 @default.
• W3216188636 cites W1828385005 @default.
• W3216188636 cites W1887230920 @default.
• W3216188636 cites W1984099286 @default.
• W3216188636 cites W2009726930 @default.
• W3216188636 cites W2012483436 @default.
• W3216188636 cites W2018305040 @default.
• W3216188636 cites W2046024437 @default.
• W3216188636 cites W2046433577 @default.
• W3216188636 cites W2084979315 @default.
• W3216188636 cites W2091226020 @default.
• W3216188636 cites W2111117940 @default.
• W3216188636 cites W2112620393 @default.
• W3216188636 cites W2114046308 @default.
• W3216188636 cites W2126189364 @default.
• W3216188636 cites W2134293572 @default.
• W3216188636 cites W2136199096 @default.
• W3216188636 cites W2150106022 @default.
• W3216188636 cites W2195752953 @default.
• W3216188636 cites W2214920251 @default.
• W3216188636 cites W2400423516 @default.
• W3216188636 cites W2460736104 @default.
• W3216188636 cites W2562017160 @default.
• W3216188636 cites W2616659710 @default.
• W3216188636 cites W2732317964 @default.
• W3216188636 cites W2733011415 @default.
• W3216188636 cites W2736307756 @default.
• W3216188636 cites W2766814675 @default.
• W3216188636 cites W2789241518 @default.
• W3216188636 cites W2884818637 @default.
• W3216188636 cites W2902969016 @default.
• W3216188636 cites W2904945948 @default.
• W3216188636 cites W2908044264 @default.
• W3216188636 cites W2967269280 @default.
• W3216188636 cites W2987498929 @default.
• W3216188636 cites W3005776865 @default.
• W3216188636 cites W3036020036 @default.
• W3216188636 cites W3036272231 @default.
• W3216188636 cites W3127908987 @default.
• W3216188636 cites W3201485209 @default.
• W3216188636 doi "https://doi.org/10.1155/2021/5171618" @default.
• W3216188636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34877358" @default.
• W3216188636 hasPublicationYear "2021" @default.
• W3216188636 type Work @default.
• W3216188636 sameAs 3216188636 @default.
• W3216188636 citedByCount "5" @default.
• W3216188636 countsByYear W32161886362022 @default.
• W3216188636 countsByYear W32161886362023 @default.
• W3216188636 crossrefType "journal-article" @default.
• W3216188636 hasAuthorship W3216188636A5026996727 @default.
• W3216188636 hasAuthorship W3216188636A5029751699 @default.
• W3216188636 hasAuthorship W3216188636A5030691366 @default.
• W3216188636 hasAuthorship W3216188636A5031303595 @default.
• W3216188636 hasAuthorship W3216188636A5031466356 @default.
• W3216188636 hasAuthorship W3216188636A5054449543 @default.
• W3216188636 hasAuthorship W3216188636A5069849278 @default.
• W3216188636 hasAuthorship W3216188636A5073830471 @default.
• W3216188636 hasAuthorship W3216188636A5091904163 @default.
• W3216188636 hasBestOaLocation W32161886361 @default.
• W3216188636 hasConcept C126322002 @default.
• W3216188636 hasConcept C134018914 @default.
• W3216188636 hasConcept C15744967 @default.
• W3216188636 hasConcept C164705383 @default.
• W3216188636 hasConcept C169760540 @default.
• W3216188636 hasConcept C2775956885 @default.
• W3216188636 hasConcept C2777655717 @default.
• W3216188636 hasConcept C2779226451 @default.
• W3216188636 hasConcept C2779991468 @default.
• W3216188636 hasConcept C2781449700 @default.
• W3216188636 hasConcept C2910068830 @default.
• W3216188636 hasConcept C3018011982 @default.
• W3216188636 hasConcept C555293320 @default.
• W3216188636 hasConcept C66324658 @default.
• W3216188636 hasConcept C71924100 @default.
• W3216188636 hasConceptScore W3216188636C126322002 @default.
• W3216188636 hasConceptScore W3216188636C134018914 @default.
• W3216188636 hasConceptScore W3216188636C15744967 @default.
• W3216188636 hasConceptScore W3216188636C164705383 @default.
• W3216188636 hasConceptScore W3216188636C169760540 @default.
• W3216188636 hasConceptScore W3216188636C2775956885 @default.
• W3216188636 hasConceptScore W3216188636C2777655717 @default.
• W3216188636 hasConceptScore W3216188636C2779226451 @default.
• W3216188636 hasConceptScore W3216188636C2779991468 @default.
• W3216188636 hasConceptScore W3216188636C2781449700 @default.

• next