FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216335753> ?p ?o ?g. }

• W3216335753 endingPage "1114" @default.
• W3216335753 startingPage "1105" @default.
• W3216335753 abstract "Sleep disturbance and fatigue are commonly reported in ankylosing spondylitis (AS) but specific prevalence and the relationship to disease control are unknown.This retrospective non-interventional observational study of data from the OPAL dataset included patients with AS (ICD code M45, M45.0 or M08.1), aged 18 to 95 years and had completed ≥ 1 sleep questionnaire between 1 January 2019 and 30 September 2020. The prevalence of insomnia and obstructive sleep apnoea were assessed using the Insomnia Severity Index (ISI) and Multivariate Apnoea Prediction Index (MAPI), respectively. Propensity score (PS) matching based on sex, age and symptom duration increased comparability between patients administered tumour necrosis factor inhibitors (TNFi) and interleukin 17A inhibitors (IL-17Ai).Four hundred ninety-five patients were included. The mean ISI total score in the overall population was 8.6 ± 6.2. Self-reported moderate or severe clinical insomnia was present in 16% and 3.2% of patients, respectively. The mean MAPI score was 0.4 ± 0.3, self-reported apnoea was identified in 31.5% of patients and the mean FACIT-Fatigue score was 36.1 ± 10.7. In the PS matched population, the only treatment-related difference was the mean MAPI score (IL-17Ai 0.4 ± 0.3 and TNFi 0.3 ± 0.2, p = 0.046). Those with poor disease control (BASDAI ≥ 4) were more likely (odds ratio [OR] 7.29, 95% CI 2.37 to 22.46, p = 0.001) to have a greater severity of insomnia symptoms than those with good disease control.In this real-world AS cohort, poor disease control was associated with sleep disturbance. Little difference in sleep disturbance was observed between biologic TNFi and IL-17Ai treatment. Key Points • Sleep disturbance and fatigue are common in patients with ankylosing spondylitis. • In our real-world cohort, self-reported apnoea was reported in one-third of patients; and one in five patients reported moderate to severe insomnia. • Those with poor disease control were more likely to experience greater sleep disturbance than those with good disease control." @default.
• W3216335753 created "2021-12-06" @default.
• W3216335753 creator A5004544171 @default.
• W3216335753 creator A5014571718 @default.
• W3216335753 creator A5018068515 @default.
• W3216335753 creator A5040650255 @default.
• W3216335753 creator A5043133571 @default.
• W3216335753 creator A5043245483 @default.
• W3216335753 creator A5063990108 @default.
• W3216335753 creator A5077279225 @default.
• W3216335753 creator A5081562584 @default.
• W3216335753 date "2021-11-26" @default.
• W3216335753 modified "2023-09-27" @default.
• W3216335753 title "Prevalence of sleep disturbance and the association between poor disease control in people with ankylosing spondylitis within the Australian clinical setting (ASLEEP study): a real-world observational study using the OPAL dataset" @default.
• W3216335753 cites W145629495 @default.
• W3216335753 cites W1950718525 @default.
• W3216335753 cites W1964192238 @default.
• W3216335753 cites W1974903457 @default.
• W3216335753 cites W1988162831 @default.
• W3216335753 cites W2003984361 @default.
• W3216335753 cites W2023517019 @default.
• W3216335753 cites W2036193982 @default.
• W3216335753 cites W2047008569 @default.
• W3216335753 cites W2048330080 @default.
• W3216335753 cites W2064576660 @default.
• W3216335753 cites W2068816941 @default.
• W3216335753 cites W2075425407 @default.
• W3216335753 cites W2087394955 @default.
• W3216335753 cites W2108488740 @default.
• W3216335753 cites W2140172200 @default.
• W3216335753 cites W2241510028 @default.
• W3216335753 cites W2410687733 @default.
• W3216335753 cites W2581631210 @default.
• W3216335753 cites W2618399580 @default.
• W3216335753 cites W2747259711 @default.
• W3216335753 cites W2905565355 @default.
• W3216335753 cites W2911856336 @default.
• W3216335753 cites W2941133182 @default.
• W3216335753 cites W3009771100 @default.
• W3216335753 cites W3022011972 @default.
• W3216335753 doi "https://doi.org/10.1007/s10067-021-05953-8" @default.
• W3216335753 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34825268" @default.
• W3216335753 hasPublicationYear "2021" @default.
• W3216335753 type Work @default.
• W3216335753 sameAs 3216335753 @default.
• W3216335753 citedByCount "4" @default.
• W3216335753 countsByYear W32163357532022 @default.
• W3216335753 countsByYear W32163357532023 @default.
• W3216335753 crossrefType "journal-article" @default.
• W3216335753 hasAuthorship W3216335753A5004544171 @default.
• W3216335753 hasAuthorship W3216335753A5014571718 @default.
• W3216335753 hasAuthorship W3216335753A5018068515 @default.
• W3216335753 hasAuthorship W3216335753A5040650255 @default.
• W3216335753 hasAuthorship W3216335753A5043133571 @default.
• W3216335753 hasAuthorship W3216335753A5043245483 @default.
• W3216335753 hasAuthorship W3216335753A5063990108 @default.
• W3216335753 hasAuthorship W3216335753A5077279225 @default.
• W3216335753 hasAuthorship W3216335753A5081562584 @default.
• W3216335753 hasBestOaLocation W32163357531 @default.
• W3216335753 hasConcept C118552586 @default.
• W3216335753 hasConcept C126322002 @default.
• W3216335753 hasConcept C1513209611 @default.
• W3216335753 hasConcept C17923572 @default.
• W3216335753 hasConcept C1862650 @default.
• W3216335753 hasConcept C23131810 @default.
• W3216335753 hasConcept C2776245837 @default.
• W3216335753 hasConcept C2776260265 @default.
• W3216335753 hasConcept C2777402515 @default.
• W3216335753 hasConcept C2777453003 @default.
• W3216335753 hasConcept C2779134260 @default.
• W3216335753 hasConcept C2779650986 @default.
• W3216335753 hasConcept C2781210498 @default.
• W3216335753 hasConcept C2908647359 @default.
• W3216335753 hasConcept C2983189541 @default.
• W3216335753 hasConcept C71924100 @default.
• W3216335753 hasConcept C99454951 @default.
• W3216335753 hasConceptScore W3216335753C118552586 @default.
• W3216335753 hasConceptScore W3216335753C126322002 @default.
• W3216335753 hasConceptScore W3216335753C1513209611 @default.
• W3216335753 hasConceptScore W3216335753C17923572 @default.
• W3216335753 hasConceptScore W3216335753C1862650 @default.
• W3216335753 hasConceptScore W3216335753C23131810 @default.
• W3216335753 hasConceptScore W3216335753C2776245837 @default.
• W3216335753 hasConceptScore W3216335753C2776260265 @default.
• W3216335753 hasConceptScore W3216335753C2777402515 @default.
• W3216335753 hasConceptScore W3216335753C2777453003 @default.
• W3216335753 hasConceptScore W3216335753C2779134260 @default.
• W3216335753 hasConceptScore W3216335753C2779650986 @default.
• W3216335753 hasConceptScore W3216335753C2781210498 @default.
• W3216335753 hasConceptScore W3216335753C2908647359 @default.
• W3216335753 hasConceptScore W3216335753C2983189541 @default.
• W3216335753 hasConceptScore W3216335753C71924100 @default.
• W3216335753 hasConceptScore W3216335753C99454951 @default.
• W3216335753 hasIssue "4" @default.
• W3216335753 hasLocation W32163357531 @default.
• W3216335753 hasLocation W32163357532 @default.
• W3216335753 hasLocation W32163357533 @default.
• W3216335753 hasOpenAccess W3216335753 @default.

• next