Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216392043> ?p ?o ?g. }
- W3216392043 abstract "Definitive closure of a patent ductus arteriosus (PDA) causes significant changes in loading conditions of the left ventricle (LV) which can lead to cardiorespiratory instability including hypotension, low cardiac output, oxygenation, and ventilation impairment. Physiological insights of the adaptation of the LV can be gained by looking at ventriculo-arterial coupling (VAC) and myocardial work-energetics. We conducted a retrospective cohort study of preterm infants with echocardiographic assessment of VAC parameters, including end-systolic and arterial elastance (EES, EA), and myocardial work indices derived from longitudinal strain analysis before and 1-h after percutaneous PDA closure. A total of 35 patients were included with mean [±SD] age at intervention of 30.8 ± 9.9 days and median [IQR] weight of 1130 [995, 1318] grams. There was a reduction in preload and stroke volume, an increase in EA (38.6 ± 11.4 vs. 60 ± 15.1 mmHg/ml/kg, p < 0.001) and in EES (72 [61.5, 109.8] vs. 91.6 [72.2, 125.2] mmHg/ml/kg, p = 0.003) post-closure. Myocardial work indices reduced after PDA closure, including global work efficiency (93.9 ± 2.3 vs. 91.1 ± 3.6%, p < 0.001). A total of 17 (48.6%) patients developed post-closure instability which was associated with younger age, lower preload, and higher EA and EES. Percutaneous PDA closure is associated with major short-term changes in VAC and myocardium energetics, which may provide novel insights on the physiology of PDA closure and on the differential vulnerability to changes in loading conditions." @default.
- W3216392043 created "2021-12-06" @default.
- W3216392043 creator A5058893935 @default.
- W3216392043 creator A5065206288 @default.
- W3216392043 creator A5085189262 @default.
- W3216392043 date "2021-11-01" @default.
- W3216392043 modified "2023-09-27" @default.
- W3216392043 title "Short‐term ventriculo‐arterial coupling and myocardial work efficiency in preterm infants undergoing percutaneous patent ductus arteriosus closure" @default.
- W3216392043 cites W1777904247 @default.
- W3216392043 cites W1792854258 @default.
- W3216392043 cites W1971849672 @default.
- W3216392043 cites W1979154217 @default.
- W3216392043 cites W1982256956 @default.
- W3216392043 cites W1983500867 @default.
- W3216392043 cites W1986409524 @default.
- W3216392043 cites W1998974649 @default.
- W3216392043 cites W1999308815 @default.
- W3216392043 cites W2000595347 @default.
- W3216392043 cites W2000678988 @default.
- W3216392043 cites W2008523461 @default.
- W3216392043 cites W2011559527 @default.
- W3216392043 cites W2015795623 @default.
- W3216392043 cites W2017911221 @default.
- W3216392043 cites W2025736240 @default.
- W3216392043 cites W2028429776 @default.
- W3216392043 cites W2030280936 @default.
- W3216392043 cites W2030332201 @default.
- W3216392043 cites W2033292054 @default.
- W3216392043 cites W2034443136 @default.
- W3216392043 cites W2034881708 @default.
- W3216392043 cites W2041557641 @default.
- W3216392043 cites W2060483616 @default.
- W3216392043 cites W2061176132 @default.
- W3216392043 cites W2062522210 @default.
- W3216392043 cites W2081590661 @default.
- W3216392043 cites W2082543306 @default.
- W3216392043 cites W2083482213 @default.
- W3216392043 cites W2098390405 @default.
- W3216392043 cites W2099016123 @default.
- W3216392043 cites W2111085257 @default.
- W3216392043 cites W2138608902 @default.
- W3216392043 cites W2146589023 @default.
- W3216392043 cites W2190938105 @default.
- W3216392043 cites W2279076616 @default.
- W3216392043 cites W2279672159 @default.
- W3216392043 cites W2302610057 @default.
- W3216392043 cites W2338311892 @default.
- W3216392043 cites W2547290215 @default.
- W3216392043 cites W2590369252 @default.
- W3216392043 cites W2591085342 @default.
- W3216392043 cites W2593163422 @default.
- W3216392043 cites W2733944801 @default.
- W3216392043 cites W2793916848 @default.
- W3216392043 cites W2891655834 @default.
- W3216392043 cites W2898967541 @default.
- W3216392043 cites W2906212871 @default.
- W3216392043 cites W2909661636 @default.
- W3216392043 cites W2927753519 @default.
- W3216392043 cites W3022183391 @default.
- W3216392043 cites W3098205344 @default.
- W3216392043 cites W3101035549 @default.
- W3216392043 cites W3107132147 @default.
- W3216392043 cites W3118866177 @default.
- W3216392043 cites W3157719056 @default.
- W3216392043 cites W4237719183 @default.
- W3216392043 cites W4243622324 @default.
- W3216392043 doi "https://doi.org/10.14814/phy2.15108" @default.
- W3216392043 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8606853" @default.
- W3216392043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34806325" @default.
- W3216392043 hasPublicationYear "2021" @default.
- W3216392043 type Work @default.
- W3216392043 sameAs 3216392043 @default.
- W3216392043 citedByCount "7" @default.
- W3216392043 countsByYear W32163920432022 @default.
- W3216392043 countsByYear W32163920432023 @default.
- W3216392043 crossrefType "journal-article" @default.
- W3216392043 hasAuthorship W3216392043A5058893935 @default.
- W3216392043 hasAuthorship W3216392043A5065206288 @default.
- W3216392043 hasAuthorship W3216392043A5085189262 @default.
- W3216392043 hasBestOaLocation W32163920431 @default.
- W3216392043 hasConcept C126322002 @default.
- W3216392043 hasConcept C164705383 @default.
- W3216392043 hasConcept C178853913 @default.
- W3216392043 hasConcept C2777953023 @default.
- W3216392043 hasConcept C2778921608 @default.
- W3216392043 hasConcept C2780813298 @default.
- W3216392043 hasConcept C2781236024 @default.
- W3216392043 hasConcept C42219234 @default.
- W3216392043 hasConcept C48277249 @default.
- W3216392043 hasConcept C71924100 @default.
- W3216392043 hasConcept C80461066 @default.
- W3216392043 hasConcept C84393581 @default.
- W3216392043 hasConceptScore W3216392043C126322002 @default.
- W3216392043 hasConceptScore W3216392043C164705383 @default.
- W3216392043 hasConceptScore W3216392043C178853913 @default.
- W3216392043 hasConceptScore W3216392043C2777953023 @default.
- W3216392043 hasConceptScore W3216392043C2778921608 @default.
- W3216392043 hasConceptScore W3216392043C2780813298 @default.
- W3216392043 hasConceptScore W3216392043C2781236024 @default.
- W3216392043 hasConceptScore W3216392043C42219234 @default.