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• W3216403971 abstract "Abstract The ecto‐5′‐nucleotidase CD73 is involved in the production of immunosuppressive adenosine in the tumoral microenvironment and recently became a validated target in immuno‐oncology. To avoid formation of CD73‐produced adenosine, several series of potential inhibitors of the target enzyme based on a triazole scaffold were synthetized and evaluated on recombinant purified h CD73 and in cell‐based assays." @default.
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• W3216403971 date "2021-12-09" @default.
• W3216403971 modified "2023-10-14" @default.
• W3216403971 title "Synthesis and Studies of Potential Inhibitors of CD73 Based on a Triazole Scaffold" @default.
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• W3216403971 doi "https://doi.org/10.1002/ejoc.202101175" @default.
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