Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216503742> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3216503742 endingPage "105316" @default.
- W3216503742 startingPage "105316" @default.
- W3216503742 abstract "This study aimed to investigate the role of lncRNA NR2F2-AS1 in oral squamous cell carcinoma cells (OSCC).The TCGA datasets were used to explore the differential expression of NR2F2-AS1 in OSCC. To further explore the potential interaction between NR2F2-AS1 and miR-494, SCC090 cells were transfected with the NR2F2-AS1 expression vector, NR2F2-AS1 siRNA, and a miR-494 mimic. The effect of NR2F2-AS1 on miR-494 methylation was evaluated by performing methylation-specific PCR (MSP). Cell Counting Kit-8 (CCK-8) assay was used to assess the effects of NR2F2-AS1 silencing and miR-494 and NR2F2-AS1 overexpression on OSCC cell proliferation.NR2F2-AS1 expression was downregulated in OSCC and positively correlated with miR-494 expression. In OSCC cells, NR2F2-AS1 overexpression upregulated miR-494 level, while NR2F2-AS1 silencing decreased miR-494 expression. MSP results showed that NR2F2-AS1 overexpression decreased miR-494 methylation while NR2F2-AS1 silencing increased miR-494 methylation. In addition, NR2F2-AS1 silencing increased OSCC cell proliferation rate while overexpression of miR-494 and NR2F2-AS1 decreased OSCC cell proliferation. Furthermore, miR-494 overexpression attenuated the effects of NR2F2-AS1 silencing on cell proliferation.NR2F2-AS1 may inhibit miR-494 methylation to regulate cell proliferation in OSCC.The analyzed data sets generated during the study are available from the corresponding author upon reasonable request." @default.
- W3216503742 created "2021-12-06" @default.
- W3216503742 creator A5013435066 @default.
- W3216503742 creator A5030570249 @default.
- W3216503742 creator A5036475263 @default.
- W3216503742 creator A5051087433 @default.
- W3216503742 creator A5066484218 @default.
- W3216503742 creator A5082768259 @default.
- W3216503742 creator A5087669657 @default.
- W3216503742 creator A5088844549 @default.
- W3216503742 creator A5091453736 @default.
- W3216503742 date "2022-02-01" @default.
- W3216503742 modified "2023-10-02" @default.
- W3216503742 title "lncRNA NR2F2-AS1 inhibits the methylation of miR-494 to regulate oral squamous cell carcinoma cell proliferation" @default.
- W3216503742 cites W1497618943 @default.
- W3216503742 cites W1918657120 @default.
- W3216503742 cites W1930806770 @default.
- W3216503742 cites W1987602380 @default.
- W3216503742 cites W2027200362 @default.
- W3216503742 cites W2042220018 @default.
- W3216503742 cites W2067291604 @default.
- W3216503742 cites W2070777085 @default.
- W3216503742 cites W2090900427 @default.
- W3216503742 cites W2098604107 @default.
- W3216503742 cites W2132080925 @default.
- W3216503742 cites W2171232664 @default.
- W3216503742 cites W2245239316 @default.
- W3216503742 cites W2542690450 @default.
- W3216503742 cites W2625600561 @default.
- W3216503742 cites W2750107048 @default.
- W3216503742 cites W2775151083 @default.
- W3216503742 cites W2907260420 @default.
- W3216503742 cites W2969823493 @default.
- W3216503742 doi "https://doi.org/10.1016/j.archoralbio.2021.105316" @default.
- W3216503742 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34896865" @default.
- W3216503742 hasPublicationYear "2022" @default.
- W3216503742 type Work @default.
- W3216503742 sameAs 3216503742 @default.
- W3216503742 citedByCount "1" @default.
- W3216503742 countsByYear W32165037422022 @default.
- W3216503742 crossrefType "journal-article" @default.
- W3216503742 hasAuthorship W3216503742A5013435066 @default.
- W3216503742 hasAuthorship W3216503742A5030570249 @default.
- W3216503742 hasAuthorship W3216503742A5036475263 @default.
- W3216503742 hasAuthorship W3216503742A5051087433 @default.
- W3216503742 hasAuthorship W3216503742A5066484218 @default.
- W3216503742 hasAuthorship W3216503742A5082768259 @default.
- W3216503742 hasAuthorship W3216503742A5087669657 @default.
- W3216503742 hasAuthorship W3216503742A5088844549 @default.
- W3216503742 hasAuthorship W3216503742A5091453736 @default.
- W3216503742 hasConcept C104317684 @default.
- W3216503742 hasConcept C119056186 @default.
- W3216503742 hasConcept C127561419 @default.
- W3216503742 hasConcept C1491633281 @default.
- W3216503742 hasConcept C150194340 @default.
- W3216503742 hasConcept C185592680 @default.
- W3216503742 hasConcept C190727270 @default.
- W3216503742 hasConcept C33288867 @default.
- W3216503742 hasConcept C502942594 @default.
- W3216503742 hasConcept C54355233 @default.
- W3216503742 hasConcept C62112901 @default.
- W3216503742 hasConcept C86803240 @default.
- W3216503742 hasConceptScore W3216503742C104317684 @default.
- W3216503742 hasConceptScore W3216503742C119056186 @default.
- W3216503742 hasConceptScore W3216503742C127561419 @default.
- W3216503742 hasConceptScore W3216503742C1491633281 @default.
- W3216503742 hasConceptScore W3216503742C150194340 @default.
- W3216503742 hasConceptScore W3216503742C185592680 @default.
- W3216503742 hasConceptScore W3216503742C190727270 @default.
- W3216503742 hasConceptScore W3216503742C33288867 @default.
- W3216503742 hasConceptScore W3216503742C502942594 @default.
- W3216503742 hasConceptScore W3216503742C54355233 @default.
- W3216503742 hasConceptScore W3216503742C62112901 @default.
- W3216503742 hasConceptScore W3216503742C86803240 @default.
- W3216503742 hasLocation W32165037421 @default.
- W3216503742 hasLocation W32165037422 @default.
- W3216503742 hasOpenAccess W3216503742 @default.
- W3216503742 hasPrimaryLocation W32165037421 @default.
- W3216503742 hasRelatedWork W2064587649 @default.
- W3216503742 hasRelatedWork W2296384492 @default.
- W3216503742 hasRelatedWork W2409290408 @default.
- W3216503742 hasRelatedWork W2540716486 @default.
- W3216503742 hasRelatedWork W2738575927 @default.
- W3216503742 hasRelatedWork W2762525387 @default.
- W3216503742 hasRelatedWork W3005549771 @default.
- W3216503742 hasRelatedWork W3206621415 @default.
- W3216503742 hasRelatedWork W4211028039 @default.
- W3216503742 hasRelatedWork W4243012653 @default.
- W3216503742 hasVolume "134" @default.
- W3216503742 isParatext "false" @default.
- W3216503742 isRetracted "false" @default.
- W3216503742 magId "3216503742" @default.
- W3216503742 workType "article" @default.