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- W3216571514 endingPage "251" @default.
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- W3216571514 abstract "Chronic stable angina pectoris, the most prevalent symptomatic manifestation of coronary artery disease, greatly impairs quality of life and is associated with an increased risk for adverse cardiovascular outcomes. Better understanding of the pathophysiologic mechanisms of myocardial ischemia permitted new therapeutic strategies to optimize the management of angina patients. Ideally, antianginal drug treatment should be tailored to individual patient’s profile and chosen according to the pathophysiology, hemodynamic profile, adverse effects, potential drug interactions and comorbidities. In this respect, and because of its peculiar mechanism of action, ranolazine represents an alternative therapeutic approach in patients with chronic stable angina and may be considered the first choice in presence of comorbidities that difficult the use of traditional therapies." @default.
- W3216571514 created "2021-12-06" @default.
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- W3216571514 date "2022-03-01" @default.
- W3216571514 modified "2023-10-16" @default.
- W3216571514 title "Ranolazine: a better understanding of its pathophysiology and patient profile to guide treatment of chronic stable angina" @default.
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- W3216571514 doi "https://doi.org/10.2217/fca-2021-0058" @default.
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