FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216808825> ?p ?o ?g. }

• W3216808825 endingPage "S274" @default.
• W3216808825 startingPage "S267" @default.
• W3216808825 abstract "Performing whole genome sequencing (WGS) for the surveillance of antimicrobial resistance offers the ability to determine not only the antimicrobials to which rates of resistance are increasing, but also the evolutionary mechanisms and transmission routes responsible for the increase at local, national, and global scales. To derive WGS-based outputs, a series of processes are required, beginning with sample and metadata collection, followed by nucleic acid extraction, library preparation, sequencing, and analysis. Throughout this pathway there are many data-related operations required (informatics) combined with more biologically focused procedures (bioinformatics). For a laboratory aiming to implement pathogen genomics, the informatics and bioinformatics activities can be a barrier to starting on the journey; for a laboratory that has already started, these activities may become overwhelming. Here we describe these data bottlenecks and how they have been addressed in laboratories in India, Colombia, Nigeria, and the Philippines, as part of the National Institute for Health Research Global Health Research Unit on Genomic Surveillance of Antimicrobial Resistance. The approaches taken include the use of reproducible data parsing pipelines and genome sequence analysis workflows, using technologies such as Data-flo, the Nextflow workflow manager, and containerization of software dependencies. By overcoming barriers to WGS implementation in countries where genome sampling for some species may be underrepresented, a body of evidence can be built to determine the concordance of antimicrobial sensitivity testing and genome-derived resistance, and novel high-risk clones and unknown mechanisms of resistance can be discovered." @default.
• W3216808825 created "2021-12-06" @default.
• W3216808825 creator A5001492240 @default.
• W3216808825 creator A5003365408 @default.
• W3216808825 creator A5007342092 @default.
• W3216808825 creator A5011095740 @default.
• W3216808825 creator A5016323140 @default.
• W3216808825 creator A5017221947 @default.
• W3216808825 creator A5019802036 @default.
• W3216808825 creator A5024807370 @default.
• W3216808825 creator A5025175772 @default.
• W3216808825 creator A5025883996 @default.
• W3216808825 creator A5027440474 @default.
• W3216808825 creator A5027478593 @default.
• W3216808825 creator A5028032976 @default.
• W3216808825 creator A5032451873 @default.
• W3216808825 creator A5033697975 @default.
• W3216808825 creator A5034200907 @default.
• W3216808825 creator A5034273635 @default.
• W3216808825 creator A5038724007 @default.
• W3216808825 creator A5040447822 @default.
• W3216808825 creator A5041176891 @default.
• W3216808825 creator A5044113217 @default.
• W3216808825 creator A5046126817 @default.
• W3216808825 creator A5051488140 @default.
• W3216808825 creator A5051772211 @default.
• W3216808825 creator A5052016639 @default.
• W3216808825 creator A5053462933 @default.
• W3216808825 creator A5053687058 @default.
• W3216808825 creator A5059064558 @default.
• W3216808825 creator A5067448657 @default.
• W3216808825 creator A5068117269 @default.
• W3216808825 creator A5068516953 @default.
• W3216808825 creator A5070366852 @default.
• W3216808825 creator A5070415975 @default.
• W3216808825 creator A5070979666 @default.
• W3216808825 creator A5071985787 @default.
• W3216808825 creator A5073869172 @default.
• W3216808825 creator A5074059400 @default.
• W3216808825 creator A5083093116 @default.
• W3216808825 creator A5083142391 @default.
• W3216808825 creator A5086055222 @default.
• W3216808825 creator A5088898946 @default.
• W3216808825 date "2021-11-25" @default.
• W3216808825 modified "2023-10-11" @default.
• W3216808825 title "Overcoming Data Bottlenecks in Genomic Pathogen Surveillance" @default.
• W3216808825 cites W2089310071 @default.
• W3216808825 cites W2107772251 @default.
• W3216808825 cites W2172096875 @default.
• W3216808825 cites W2342249984 @default.
• W3216808825 cites W2464805220 @default.
• W3216808825 cites W2551267404 @default.
• W3216808825 cites W2560057613 @default.
• W3216808825 cites W2605897695 @default.
• W3216808825 cites W2613409207 @default.
• W3216808825 cites W2766658767 @default.
• W3216808825 cites W2808343649 @default.
• W3216808825 cites W2899068429 @default.
• W3216808825 cites W2917207851 @default.
• W3216808825 cites W2941864079 @default.
• W3216808825 cites W2954309769 @default.
• W3216808825 cites W2968322804 @default.
• W3216808825 cites W2997069256 @default.
• W3216808825 cites W3005670610 @default.
• W3216808825 cites W3006653136 @default.
• W3216808825 cites W3030261765 @default.
• W3216808825 cites W3042493313 @default.
• W3216808825 cites W3156723047 @default.
• W3216808825 cites W3162760699 @default.
• W3216808825 cites W3215757311 @default.
• W3216808825 cites W3217467414 @default.
• W3216808825 doi "https://doi.org/10.1093/cid/ciab785" @default.
• W3216808825 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8634317" @default.
• W3216808825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34850839" @default.
• W3216808825 hasPublicationYear "2021" @default.
• W3216808825 type Work @default.
• W3216808825 sameAs 3216808825 @default.
• W3216808825 citedByCount "11" @default.
• W3216808825 countsByYear W32168088252021 @default.
• W3216808825 countsByYear W32168088252022 @default.
• W3216808825 countsByYear W32168088252023 @default.
• W3216808825 crossrefType "journal-article" @default.
• W3216808825 hasAuthorship W3216808825A5001492240 @default.
• W3216808825 hasAuthorship W3216808825A5003365408 @default.
• W3216808825 hasAuthorship W3216808825A5007342092 @default.
• W3216808825 hasAuthorship W3216808825A5011095740 @default.
• W3216808825 hasAuthorship W3216808825A5016323140 @default.
• W3216808825 hasAuthorship W3216808825A5017221947 @default.
• W3216808825 hasAuthorship W3216808825A5019802036 @default.
• W3216808825 hasAuthorship W3216808825A5024807370 @default.
• W3216808825 hasAuthorship W3216808825A5025175772 @default.
• W3216808825 hasAuthorship W3216808825A5025883996 @default.
• W3216808825 hasAuthorship W3216808825A5027440474 @default.
• W3216808825 hasAuthorship W3216808825A5027478593 @default.
• W3216808825 hasAuthorship W3216808825A5028032976 @default.
• W3216808825 hasAuthorship W3216808825A5032451873 @default.
• W3216808825 hasAuthorship W3216808825A5033697975 @default.
• W3216808825 hasAuthorship W3216808825A5034200907 @default.

• next