FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3216855534> ?p ?o ?g. }

• W3216855534 endingPage "254" @default.
• W3216855534 startingPage "243" @default.
• W3216855534 abstract "Myocardial injury (MI) is a common complication of sepsis. MicroRNAs (miRNAs) have been suggested as potential biomarkers of MI; however, their mechanisms in sepsis-induced MI remain unclear. A sepsis rat model was constructed by use of cecal ligation and puncture (CLP). The levels of miR-195-5p and activating transcription factor 6 (ATF6) expression were determined by quantitative reverse-transcription polymerase chain reaction, and cytokine levels were detected by ELISA. The levels of oxidative stress (OS)-related indicators and endoplasmic reticulum stress (ERS)-related proteins were examined, and the regulatory effect of miR-195-5p on ATF6 was determined by using the luciferase reporter assay. Our results showed that miR-195-5p expression was downregulated and ATF6 expression was upregulated in lipopolysaccharide-induced cardiomyocytes and mice with CLP-induced sepsis. We also found that miR-195-5p could markedly attenuate the inflammation, apoptosis, OS, and ERS associated with sepsis-induced MI. Additionally, we verified that miR-195-5p could relieve sepsis-induced MI by targeting ATF6. This study identified potential targets for treating MI after sepsis." @default.
• W3216855534 created "2021-12-06" @default.
• W3216855534 creator A5004646219 @default.
• W3216855534 creator A5007495967 @default.
• W3216855534 creator A5017905940 @default.
• W3216855534 creator A5034028783 @default.
• W3216855534 creator A5041125267 @default.
• W3216855534 creator A5058963904 @default.
• W3216855534 date "2021-12-02" @default.
• W3216855534 modified "2023-09-27" @default.
• W3216855534 title "MiR‐195‐5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis‐induced myocardial injury by targeting activating transcription factor 6" @default.
• W3216855534 cites W1835356979 @default.
• W3216855534 cites W1980766724 @default.
• W3216855534 cites W2068133291 @default.
• W3216855534 cites W2144589352 @default.
• W3216855534 cites W2233779849 @default.
• W3216855534 cites W2270601398 @default.
• W3216855534 cites W2302279046 @default.
• W3216855534 cites W2322565284 @default.
• W3216855534 cites W2396212074 @default.
• W3216855534 cites W2485226307 @default.
• W3216855534 cites W2545733225 @default.
• W3216855534 cites W2568922166 @default.
• W3216855534 cites W2580344176 @default.
• W3216855534 cites W2610040086 @default.
• W3216855534 cites W2734323448 @default.
• W3216855534 cites W2747744817 @default.
• W3216855534 cites W2753899838 @default.
• W3216855534 cites W2761040354 @default.
• W3216855534 cites W2770265911 @default.
• W3216855534 cites W2774868879 @default.
• W3216855534 cites W2792873358 @default.
• W3216855534 cites W2799795532 @default.
• W3216855534 cites W2801610489 @default.
• W3216855534 cites W2809044574 @default.
• W3216855534 cites W2810805303 @default.
• W3216855534 cites W2886677163 @default.
• W3216855534 cites W2912767343 @default.
• W3216855534 cites W2966678846 @default.
• W3216855534 cites W2996643695 @default.
• W3216855534 cites W3007057048 @default.
• W3216855534 cites W3092945492 @default.
• W3216855534 cites W4232006188 @default.
• W3216855534 cites W4247544731 @default.
• W3216855534 doi "https://doi.org/10.1002/cbin.11726" @default.
• W3216855534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34816499" @default.
• W3216855534 hasPublicationYear "2021" @default.
• W3216855534 type Work @default.
• W3216855534 sameAs 3216855534 @default.
• W3216855534 citedByCount "7" @default.
• W3216855534 countsByYear W32168555342022 @default.
• W3216855534 countsByYear W32168555342023 @default.
• W3216855534 crossrefType "journal-article" @default.
• W3216855534 hasAuthorship W3216855534A5004646219 @default.
• W3216855534 hasAuthorship W3216855534A5007495967 @default.
• W3216855534 hasAuthorship W3216855534A5017905940 @default.
• W3216855534 hasAuthorship W3216855534A5034028783 @default.
• W3216855534 hasAuthorship W3216855534A5041125267 @default.
• W3216855534 hasAuthorship W3216855534A5058963904 @default.
• W3216855534 hasConcept C104317684 @default.
• W3216855534 hasConcept C126322002 @default.
• W3216855534 hasConcept C127561419 @default.
• W3216855534 hasConcept C139447449 @default.
• W3216855534 hasConcept C145059251 @default.
• W3216855534 hasConcept C158617107 @default.
• W3216855534 hasConcept C185592680 @default.
• W3216855534 hasConcept C190283241 @default.
• W3216855534 hasConcept C203014093 @default.
• W3216855534 hasConcept C2776151105 @default.
• W3216855534 hasConcept C2776914184 @default.
• W3216855534 hasConcept C2778384902 @default.
• W3216855534 hasConcept C2778690821 @default.
• W3216855534 hasConcept C2778754761 @default.
• W3216855534 hasConcept C2778997996 @default.
• W3216855534 hasConcept C55493867 @default.
• W3216855534 hasConcept C71924100 @default.
• W3216855534 hasConcept C86339819 @default.
• W3216855534 hasConcept C86803240 @default.
• W3216855534 hasConcept C95444343 @default.
• W3216855534 hasConceptScore W3216855534C104317684 @default.
• W3216855534 hasConceptScore W3216855534C126322002 @default.
• W3216855534 hasConceptScore W3216855534C127561419 @default.
• W3216855534 hasConceptScore W3216855534C139447449 @default.
• W3216855534 hasConceptScore W3216855534C145059251 @default.
• W3216855534 hasConceptScore W3216855534C158617107 @default.
• W3216855534 hasConceptScore W3216855534C185592680 @default.
• W3216855534 hasConceptScore W3216855534C190283241 @default.
• W3216855534 hasConceptScore W3216855534C203014093 @default.
• W3216855534 hasConceptScore W3216855534C2776151105 @default.
• W3216855534 hasConceptScore W3216855534C2776914184 @default.
• W3216855534 hasConceptScore W3216855534C2778384902 @default.
• W3216855534 hasConceptScore W3216855534C2778690821 @default.
• W3216855534 hasConceptScore W3216855534C2778754761 @default.
• W3216855534 hasConceptScore W3216855534C2778997996 @default.
• W3216855534 hasConceptScore W3216855534C55493867 @default.
• W3216855534 hasConceptScore W3216855534C71924100 @default.
• W3216855534 hasConceptScore W3216855534C86339819 @default.
• W3216855534 hasConceptScore W3216855534C86803240 @default.

• next