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- W3216939352 abstract "Therapeutic HIFU has been used as a non-invasive energy modality to compromise nerve function since the 1950s. Several contributions have been made in recent years to characterize these effects on nerve function. In this study, short repeated bursts of HIFU, termed as pulsed high intensity focused ultrasound (pHIFU), was directed at nerve tissue. The pHIFU transducer operated at a central frequency of 1.95 MHz and had a focal length of approximately 12 cm. The ventral nerve cord from the American Lobster (Homarus americanus), n=15, was sonicated cumulatively at 3 exposure times: 1s, 6s, and 16s, at an intensity of 1010 W/cm2, or focal pressure of 5.51 MPa. The compound action potential (CAP) and conduction velocity (CV) were seen to decrease as sonication exposure time to the nerve increased. The experiments performed demonstrate the feasibility to modulate nerve CAP and nerve CV using non-thermal mechanisms of ultrasound." @default.
- W3216939352 created "2021-12-06" @default.
- W3216939352 creator A5014051058 @default.
- W3216939352 date "2021-05-22" @default.
- W3216939352 modified "2023-09-23" @default.
- W3216939352 title "Effect of pulsed high intensity focused ultrasound on the nerve compound action potential amplitude and conduction velocity" @default.
- W3216939352 doi "https://doi.org/10.32920/ryerson.14648499.v1" @default.
- W3216939352 hasPublicationYear "2021" @default.
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