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• W3217059373 abstract "Social interactions are motivated behaviors that, in many species, facilitate learning. However, how the brain encodes the reinforcing properties of social interactions remains unclear. In this study, using in vivo recording in freely moving mice, we show that dopamine (DA) neurons of the ventral tegmental area (VTA) increase their activity during interactions with an unfamiliar conspecific and display heterogeneous responses. Using a social instrumental task, we then show that VTA DA neuron activity encodes social prediction error and drives social reinforcement learning. Thus, our findings suggest that VTA DA neurons are a neural substrate for a social learning signal that drives motivated behavior." @default.
• W3217059373 created "2021-12-06" @default.
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• W3217059373 date "2021-12-02" @default.
• W3217059373 modified "2023-10-18" @default.
• W3217059373 title "VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error" @default.
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• W3217059373 doi "https://doi.org/10.1038/s41593-021-00972-9" @default.
• W3217059373 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34857949" @default.
• W3217059373 hasPublicationYear "2021" @default.
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