FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3217073835> ?p ?o ?g. }

• W3217073835 endingPage "144" @default.
• W3217073835 startingPage "132" @default.
• W3217073835 abstract "<b><i>Backgroud/Objectives:</i></b> Transoral laser laryngeal microsurgery (_LTLM) has been widely used in the treatment of early-stage glottic laryngeal squamous cell carcinoma (LSCC) for the past few decades. Although T stage, tumor grade, anterior commissure involvement, type of cordectomy, positive surgical margin, and postoperative additional therapies were accused as the prognostic factors for recurrence, there is still controversy about these data in the literature. The purpose of this study was to evaluate the oncological results of our patients with early glottic LSCC treated with _LTLM as a single-modality therapy in a single-center study. <b><i>Methods:</i></b> Patients with early-stage (T_is-1–2/N₀) glottic LSCC who underwent _LTLM as a primary treatment from 2011 to 2019 were retrospectively reviewed. The clinicopathological factors and oncologic outcomes were analyzed. <b><i>Results:</i></b> One hundred and sixty-one patients were enrolled in this study. The 5-year overall (OS), disease-specific (DSS), disease-free (DFS), and laryngectomy-free survival rates were 84.5%, 97.9%, 79.2%, and 93.5%, respectively. The most common stage, histopathological type, and type of endoscopic cordectomy were T₁ stage, well-differentiated cancer, and type 2 cordectomy, respectively. A positive surgical margin was defined in 20 (12.4%) patients. There was a significant relationship between histopathological grade and positive surgical margins (<i>p</i> = 0.038). OS and DSS rates of “wait and see” modality were lower, while DFS of radiotherapy was lower than that of other treatment modalities in patients with positive surgical margins, but the differences were not statistically significant. Nineteen (11.8%) patients had a recurrence. DSS was statistically significantly lower in patients with recurrence (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The results of our study showed that anterior commissure involvement, surgical margin positivity, and higher T stage statistically did not reduce survival rates in early-stage LSCC patients treated with _LTLM. As the histopathological grade of the tumor worsens, the risk of surgical margin positivity increases. RT may have a negative effect on recurrence and organ preservation in the additional treatment of patient with positive surgical margins." @default.
• W3217073835 created "2021-12-06" @default.
• W3217073835 creator A5002120725 @default.
• W3217073835 creator A5002231802 @default.
• W3217073835 creator A5002903680 @default.
• W3217073835 creator A5043623080 @default.
• W3217073835 creator A5063218605 @default.
• W3217073835 creator A5065340630 @default.
• W3217073835 creator A5077710220 @default.
• W3217073835 creator A5081810238 @default.
• W3217073835 creator A5084273167 @default.
• W3217073835 date "2021-11-24" @default.
• W3217073835 modified "2023-09-29" @default.
• W3217073835 title "Oncological Outcomes of Transoral Laryngeal Microsurgery with Fiber-Optic Diode Laser for Early Glottic Cancer: A Single-Center Experience" @default.
• W3217073835 cites W1824157992 @default.
• W3217073835 cites W1950698100 @default.
• W3217073835 cites W1963460078 @default.
• W3217073835 cites W1966390770 @default.
• W3217073835 cites W1969398746 @default.
• W3217073835 cites W1974578350 @default.
• W3217073835 cites W1984427458 @default.
• W3217073835 cites W1992028559 @default.
• W3217073835 cites W1997803625 @default.
• W3217073835 cites W2006834181 @default.
• W3217073835 cites W2023840357 @default.
• W3217073835 cites W2037259629 @default.
• W3217073835 cites W2038161274 @default.
• W3217073835 cites W2053807055 @default.
• W3217073835 cites W2054845014 @default.
• W3217073835 cites W2066082239 @default.
• W3217073835 cites W2084062757 @default.
• W3217073835 cites W2098020551 @default.
• W3217073835 cites W2098049165 @default.
• W3217073835 cites W2119717019 @default.
• W3217073835 cites W2123522212 @default.
• W3217073835 cites W2140843986 @default.
• W3217073835 cites W2167606344 @default.
• W3217073835 cites W2169982367 @default.
• W3217073835 cites W2283745375 @default.
• W3217073835 cites W2318505815 @default.
• W3217073835 cites W2324054969 @default.
• W3217073835 cites W2415713670 @default.
• W3217073835 cites W2514542749 @default.
• W3217073835 cites W2531077037 @default.
• W3217073835 cites W2560710349 @default.
• W3217073835 cites W2569264958 @default.
• W3217073835 cites W2593165985 @default.
• W3217073835 cites W2735061302 @default.
• W3217073835 cites W2766349939 @default.
• W3217073835 cites W2789484773 @default.
• W3217073835 cites W2789607452 @default.
• W3217073835 cites W2792664644 @default.
• W3217073835 cites W2800333224 @default.
• W3217073835 cites W2805529209 @default.
• W3217073835 cites W2884222446 @default.
• W3217073835 cites W2889646458 @default.
• W3217073835 cites W2909890407 @default.
• W3217073835 cites W2941280397 @default.
• W3217073835 cites W2942689058 @default.
• W3217073835 cites W2970991682 @default.
• W3217073835 cites W2972193436 @default.
• W3217073835 cites W2990681162 @default.
• W3217073835 doi "https://doi.org/10.1159/000519718" @default.
• W3217073835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34818662" @default.
• W3217073835 hasPublicationYear "2021" @default.
• W3217073835 type Work @default.
• W3217073835 sameAs 3217073835 @default.
• W3217073835 citedByCount "1" @default.
• W3217073835 countsByYear W32170738352023 @default.
• W3217073835 crossrefType "journal-article" @default.
• W3217073835 hasAuthorship W3217073835A5002120725 @default.
• W3217073835 hasAuthorship W3217073835A5002231802 @default.
• W3217073835 hasAuthorship W3217073835A5002903680 @default.
• W3217073835 hasAuthorship W3217073835A5043623080 @default.
• W3217073835 hasAuthorship W3217073835A5063218605 @default.
• W3217073835 hasAuthorship W3217073835A5065340630 @default.
• W3217073835 hasAuthorship W3217073835A5077710220 @default.
• W3217073835 hasAuthorship W3217073835A5081810238 @default.
• W3217073835 hasAuthorship W3217073835A5084273167 @default.
• W3217073835 hasConcept C121608353 @default.
• W3217073835 hasConcept C126322002 @default.
• W3217073835 hasConcept C141071460 @default.
• W3217073835 hasConcept C146357865 @default.
• W3217073835 hasConcept C151730666 @default.
• W3217073835 hasConcept C2776957994 @default.
• W3217073835 hasConcept C2778993000 @default.
• W3217073835 hasConcept C2779048510 @default.
• W3217073835 hasConcept C2780073493 @default.
• W3217073835 hasConcept C2780091936 @default.
• W3217073835 hasConcept C2780474809 @default.
• W3217073835 hasConcept C2781157581 @default.
• W3217073835 hasConcept C71924100 @default.
• W3217073835 hasConcept C86803240 @default.
• W3217073835 hasConceptScore W3217073835C121608353 @default.
• W3217073835 hasConceptScore W3217073835C126322002 @default.
• W3217073835 hasConceptScore W3217073835C141071460 @default.
• W3217073835 hasConceptScore W3217073835C146357865 @default.
• W3217073835 hasConceptScore W3217073835C151730666 @default.

• next