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- W3217079356 abstract "<b>Background:</b> Chronic Obstructive Pulmonary Disease (COPD) results of the interaction between genetic and environmental factors. The influence of the gender is still controverse. <b>Aim:</b> Assess gender differences regarding proportion and predicted factors for COPD diagnosis. <b>Methods:</b> We included individuals aged ≥40 years with smoking habits ≥10 pack year (PY), who performed spirometry in a Lung Function Laboratory of Hospital da Luz Lisbon for 4 months. Individuals with respiratory disease, under bronchodilator and respiratory symptoms (RS) unknown were excluded. Standardized and non-standardized coefficients logistic regression models for COPD diagnosis for both genders were determined using as predictors age, body mass index (BMI), smoking status, PY and presence of RS. A global logistic regression model was also obtained. <b>Results:</b> We included 241 individuals, 134 were male. The COPD diagnosis was 20.9% within male group and 13.1% within female group, without differences (p=0.156). Age was a risk factor for COPD (male:OR 1.052; CI95% 1.002-1.109.female: OR 1.108; CI95% 1.021-1.216) as well as the presence of RS (male:OR 4.990; CI95% 1.863-14.544.female: OR 3.818; CI95% 1.014-17.662). Current smoker status had a significantly greater risk among female (OR 7.5834; CI95% 1.545–62.870 vs OR 0.9317; CI95% 0.316-2.728). The presence of RS had the highest absolute coefficient for the male and the current smoker status for the female model. Interaction between gender and current smoker status was statistically significant (p=0.048). <b>Conclusion:</b> We did not find differences in COPD prevalence between gender. Different factors could be related with different risk for COPD according the gender. Current smoker seems to have higher risk among female." @default.
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- W3217079356 date "2021-09-05" @default.
- W3217079356 modified "2023-09-25" @default.
- W3217079356 title "COPD DIAGNOSIS: DIFFERENCES ACCORDING GENDER" @default.
- W3217079356 doi "https://doi.org/10.1183/13993003.congress-2021.pa1014" @default.
- W3217079356 hasPublicationYear "2021" @default.
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