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- W3217106323 abstract "Pasteurella multocida is a multispecies pathogen with certain host specific capsular types but interspecies transmission cannot be overlooked. Knowing the diversity of P. multocida in a geographical location is essential to formulate a vaccination programme. Diversity among the P. multocida isolates from different avian species recovered in the state of Tamil Nadu, India was studied using enterobacterial repetitive intergenic consensus region (ERIC)-PCR and virulence gene profiling (VP). Capsular typing revealed that 44 (97.78%) strains belonged to capsular type A while only one (2.22%) strain belonged to capsular type B. ERIC-PCR analysis showed eight different clusters and four individual strains. The index of discrimination (D value) was found to be 0.8899. Virulence profiling showed that genes fimA, pfhA, hsf-2 and pmHAS were found in 100% of the strains while ompH, omp87, ompA, plpB, sodA, sodC, ptfA, hsf-1, exbB, fur, hgbA and hgbB were found in ≥90% of the strains. Dermonecrotoxin gene toxA was present only in 4.44% of the strains, while nanH in 68.89% and nanB in 88.89% of the strains. One strain each from turkey and Guinea fowl had toxA gene. Correlation analysis revealed a positive correlation between ptfA and hgbA gene, exbB and fur gene, ptfA and sodC gene, exbB and hsf-1 gene, ompA and ompH gene. Majority of duck strains clustered together both in ERIC and virulence gene profiles. Turkey strains were highly diverse with different VPs and ERIC-PCR patterns." @default.
- W3217106323 created "2021-12-06" @default.
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- W3217106323 date "2021-12-01" @default.
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- W3217106323 title "Virulence genes and enterobacterial repetitive intergenic consensus region (ERIC) profiling reveals highly diverse genetic population among avian strains of Pasteurella multocida" @default.
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- W3217106323 doi "https://doi.org/10.1016/j.micpath.2021.105303" @default.
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