Matches in SemOpenAlex for { <https://semopenalex.org/work/W3217161873> ?p ?o ?g. }
- W3217161873 endingPage "661" @default.
- W3217161873 startingPage "661" @default.
- W3217161873 abstract "Organic extracts of marine invertebrates, mainly sponges, from seas all over the world are well known for their high in vitro anticancer and antibiotic activities which make them promising sources of compounds with potential use as pharmaceutical leads. Most of the structures discovered so far have a peculiar structural feature in common: a 1,2-dioxane ring. This is a highly reactive heterocycle that can be considered as an endoperoxide function. Together with other structural features, this group could be responsible for the strong biological activities of the substances present in the extracts. Numerous research programs have focused on their structural elucidation and total synthesis since the seventies. As a consequence, the number of established chiral centres and the similarity between different naturally occurring substances is increasingly higher. Most of these compounds have a terpenoid nature, mainly diterpene and sesterterpene, with several peculiar structural features, such as the loss of one carbon atom. Although there are many reviews dealing with the occurrence of marine peroxides, their activities, or potential pharmaceutical uses, no one has focused on those having a terpene origin and the endoperoxide function. We present here a comprehensive review of these compounds paying special attention to their structural features and their biological activity." @default.
- W3217161873 created "2021-12-06" @default.
- W3217161873 creator A5011325165 @default.
- W3217161873 creator A5018804947 @default.
- W3217161873 creator A5046908655 @default.
- W3217161873 creator A5068695823 @default.
- W3217161873 creator A5076973369 @default.
- W3217161873 date "2021-11-25" @default.
- W3217161873 modified "2023-10-17" @default.
- W3217161873 title "Marine Terpenic Endoperoxides" @default.
- W3217161873 cites W1556217778 @default.
- W3217161873 cites W1583142517 @default.
- W3217161873 cites W1772296661 @default.
- W3217161873 cites W193598101 @default.
- W3217161873 cites W1964815276 @default.
- W3217161873 cites W1964875647 @default.
- W3217161873 cites W1966004165 @default.
- W3217161873 cites W1966181878 @default.
- W3217161873 cites W1969309264 @default.
- W3217161873 cites W1971799924 @default.
- W3217161873 cites W1972686059 @default.
- W3217161873 cites W1975883544 @default.
- W3217161873 cites W1976319341 @default.
- W3217161873 cites W1980526996 @default.
- W3217161873 cites W1983270216 @default.
- W3217161873 cites W1983938275 @default.
- W3217161873 cites W1989122924 @default.
- W3217161873 cites W1990066684 @default.
- W3217161873 cites W1992289048 @default.
- W3217161873 cites W1993612705 @default.
- W3217161873 cites W1993990585 @default.
- W3217161873 cites W1997385896 @default.
- W3217161873 cites W1999423758 @default.
- W3217161873 cites W2001760324 @default.
- W3217161873 cites W2006326711 @default.
- W3217161873 cites W2007744435 @default.
- W3217161873 cites W2008347986 @default.
- W3217161873 cites W2011149977 @default.
- W3217161873 cites W2016873997 @default.
- W3217161873 cites W2017132164 @default.
- W3217161873 cites W2018537588 @default.
- W3217161873 cites W2027317141 @default.
- W3217161873 cites W2030927745 @default.
- W3217161873 cites W2033770273 @default.
- W3217161873 cites W2042968636 @default.
- W3217161873 cites W2043037705 @default.
- W3217161873 cites W2044073976 @default.
- W3217161873 cites W2044427893 @default.
- W3217161873 cites W2046973137 @default.
- W3217161873 cites W2049182863 @default.
- W3217161873 cites W2056800643 @default.
- W3217161873 cites W2059791701 @default.
- W3217161873 cites W2060742488 @default.
- W3217161873 cites W2060790676 @default.
- W3217161873 cites W2062726560 @default.
- W3217161873 cites W2063057239 @default.
- W3217161873 cites W2063678170 @default.
- W3217161873 cites W2065227079 @default.
- W3217161873 cites W2066300890 @default.
- W3217161873 cites W2067710402 @default.
- W3217161873 cites W2070178250 @default.
- W3217161873 cites W2079404292 @default.
- W3217161873 cites W2081530256 @default.
- W3217161873 cites W2083374507 @default.
- W3217161873 cites W2084384524 @default.
- W3217161873 cites W2084485740 @default.
- W3217161873 cites W2085684276 @default.
- W3217161873 cites W2086551847 @default.
- W3217161873 cites W2089059979 @default.
- W3217161873 cites W2089201177 @default.
- W3217161873 cites W2089700556 @default.
- W3217161873 cites W2091084038 @default.
- W3217161873 cites W2093030347 @default.
- W3217161873 cites W2106172229 @default.
- W3217161873 cites W2107856756 @default.
- W3217161873 cites W2285362077 @default.
- W3217161873 cites W2315900140 @default.
- W3217161873 cites W2322598986 @default.
- W3217161873 cites W2323943045 @default.
- W3217161873 cites W2334349132 @default.
- W3217161873 cites W2394660635 @default.
- W3217161873 cites W2403832768 @default.
- W3217161873 cites W2430454914 @default.
- W3217161873 cites W2508538812 @default.
- W3217161873 cites W2757141237 @default.
- W3217161873 cites W2790324795 @default.
- W3217161873 cites W2911442634 @default.
- W3217161873 cites W2913713634 @default.
- W3217161873 cites W2949529315 @default.
- W3217161873 cites W2949943691 @default.
- W3217161873 cites W2950713584 @default.
- W3217161873 cites W2951739233 @default.
- W3217161873 cites W2952272760 @default.
- W3217161873 cites W2952471031 @default.
- W3217161873 cites W2953111757 @default.
- W3217161873 cites W3004600529 @default.
- W3217161873 cites W3007625921 @default.
- W3217161873 cites W3035835645 @default.