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• W3217287761 abstract "A novel tumor-related biomarker, a H2O2-activatable photosensitizer 4 based on the 1,3-dicarbonyl enol moieties of hypocrellin B (3), was designed and synthesized. The photosensitizer 4 showed a blue-shifted absorption band compared with 3, and showed negligible photosensitizing ability without H2O2. However, the release of 3 from 4 by the reaction with H2O2 regenerated the photosensitizing ability. Furthermore, 4 exhibited selective and effective photo-cytotoxicity against high H2O2-expressing cancer cells upon photo-irradiation with 660 nm light, which is inside the phototherapeutic window." @default.
• W3217287761 created "2021-12-06" @default.
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• W3217287761 date "2022-01-01" @default.
• W3217287761 modified "2023-10-15" @default.
• W3217287761 title "Hypocrellin B-based activatable photosensitizers for specific photodynamic effects against high H₂O₂-expressing cancer cells" @default.
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• W3217287761 doi "https://doi.org/10.1039/d1cc05823a" @default.
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