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- W3217381985 abstract "ABSTRACT Background SARS-CoV-2 vaccination might impact on clinical progression of cases with breakthrough COVID-19 disease. Objective to evaluate the impact of SARS-CoV-2 vaccination on disease progression in COVID-19 hospitalized patient Methods and Findings Two-hundred eighty-four consecutive COVID-19 hospitalized patients, including 50 vaccinated cases entered the study. Compared to unvaccinated cases, vaccinated patients were older, exhibited more comorbidities and did not differ for COVID-19 severity at admission. During hospitalisation, unvaccinated patients showed worse disease progression, including higher need of oxygen and higher risk of death compared to vaccinated patients (OR 3.3; 1.05-10.7 95% CI in the whole cohort and OR 54.8; 3.5-852 in the ventilated cases). Discussion These findings argue for an important reduction in severity among vaccine breakthrough infection compared to unvaccinated cases in COVID-19 disease." @default.
- W3217381985 created "2021-12-06" @default.
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- W3217381985 date "2021-11-26" @default.
- W3217381985 modified "2023-10-06" @default.
- W3217381985 title "SARS-CoV-2 vaccination predicts COVID-19 progression and outcomes in hospitalized patients" @default.
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- W3217381985 doi "https://doi.org/10.1101/2021.11.21.21266633" @default.
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