Matches in SemOpenAlex for { <https://semopenalex.org/work/W3217490912> ?p ?o ?g. }
- W3217490912 endingPage "101515" @default.
- W3217490912 startingPage "101515" @default.
- W3217490912 abstract "The hypothesis that pain can predispose to frailty development has been recently investigated in several clinical studies suggesting that frailty and pain may share some mechanisms. Both pain and frailty represent important clinical and social problems and both lack a successful treatment. This circumstance is mainly due to the absence of in-depth knowledge of their pathological mechanisms. Evidence of shared pathways between frailty and pain are preliminary. Indeed, many clinical studies are observational and the impact of pain treatment, and relative pain-relief, on frailty onset and progression has never been investigated. Furthermore, preclinical research on this topic has yet to be performed. Specific researches on the pain-frailty relation are needed. In this narrative review, we will attempt to point out the most relevant findings present in both clinical and preclinical literature on the topic, with particular attention to genetics, epigenetics and inflammation, in order to underline the existing gaps and the potential future interventional strategies. The use of pain and frailty animal models discussed in this review might contribute to research in this area." @default.
- W3217490912 created "2021-12-06" @default.
- W3217490912 creator A5001206855 @default.
- W3217490912 creator A5017553473 @default.
- W3217490912 creator A5028449400 @default.
- W3217490912 creator A5067038903 @default.
- W3217490912 creator A5069619677 @default.
- W3217490912 creator A5076936941 @default.
- W3217490912 creator A5082279696 @default.
- W3217490912 creator A5082929777 @default.
- W3217490912 date "2022-01-01" @default.
- W3217490912 modified "2023-09-26" @default.
- W3217490912 title "Frailty and pain, human studies and animal models" @default.
- W3217490912 cites W1486868167 @default.
- W3217490912 cites W1525057973 @default.
- W3217490912 cites W1705809348 @default.
- W3217490912 cites W1726979551 @default.
- W3217490912 cites W1793532565 @default.
- W3217490912 cites W1858465734 @default.
- W3217490912 cites W1873874031 @default.
- W3217490912 cites W1905555261 @default.
- W3217490912 cites W1944231772 @default.
- W3217490912 cites W1965866432 @default.
- W3217490912 cites W1969705982 @default.
- W3217490912 cites W1972810913 @default.
- W3217490912 cites W1973239744 @default.
- W3217490912 cites W1974357563 @default.
- W3217490912 cites W1975412844 @default.
- W3217490912 cites W1975585602 @default.
- W3217490912 cites W1979729748 @default.
- W3217490912 cites W1980082002 @default.
- W3217490912 cites W1980990177 @default.
- W3217490912 cites W1981238311 @default.
- W3217490912 cites W1986926865 @default.
- W3217490912 cites W1987479668 @default.
- W3217490912 cites W1991372502 @default.
- W3217490912 cites W1991466123 @default.
- W3217490912 cites W1992398234 @default.
- W3217490912 cites W1994143270 @default.
- W3217490912 cites W1996525778 @default.
- W3217490912 cites W1997566081 @default.
- W3217490912 cites W1998379849 @default.
- W3217490912 cites W2001145951 @default.
- W3217490912 cites W2001946273 @default.
- W3217490912 cites W2003675005 @default.
- W3217490912 cites W2004024190 @default.
- W3217490912 cites W2005692725 @default.
- W3217490912 cites W2005733093 @default.
- W3217490912 cites W2008634539 @default.
- W3217490912 cites W2011604885 @default.
- W3217490912 cites W2017357594 @default.
- W3217490912 cites W2019429714 @default.
- W3217490912 cites W2021853257 @default.
- W3217490912 cites W2021904427 @default.
- W3217490912 cites W2022338924 @default.
- W3217490912 cites W2026180657 @default.
- W3217490912 cites W202656759 @default.
- W3217490912 cites W2028186017 @default.
- W3217490912 cites W2028269583 @default.
- W3217490912 cites W2031422006 @default.
- W3217490912 cites W2040484651 @default.
- W3217490912 cites W2040625818 @default.
- W3217490912 cites W2040936681 @default.
- W3217490912 cites W2042143222 @default.
- W3217490912 cites W2044299609 @default.
- W3217490912 cites W2044704715 @default.
- W3217490912 cites W2045486314 @default.
- W3217490912 cites W2046957298 @default.
- W3217490912 cites W2047010161 @default.
- W3217490912 cites W2049956841 @default.
- W3217490912 cites W2050458294 @default.
- W3217490912 cites W2050646098 @default.
- W3217490912 cites W2054126115 @default.
- W3217490912 cites W2054566584 @default.
- W3217490912 cites W2054675033 @default.
- W3217490912 cites W2055887038 @default.
- W3217490912 cites W2058020736 @default.
- W3217490912 cites W2058878920 @default.
- W3217490912 cites W2061743196 @default.
- W3217490912 cites W2063985582 @default.
- W3217490912 cites W2065262203 @default.
- W3217490912 cites W2065809502 @default.
- W3217490912 cites W2067476075 @default.
- W3217490912 cites W2067924690 @default.
- W3217490912 cites W2071700706 @default.
- W3217490912 cites W2071841250 @default.
- W3217490912 cites W2071998530 @default.
- W3217490912 cites W2077885131 @default.
- W3217490912 cites W2079863333 @default.
- W3217490912 cites W2081806943 @default.
- W3217490912 cites W2082286201 @default.
- W3217490912 cites W2082402714 @default.
- W3217490912 cites W2083590269 @default.
- W3217490912 cites W2084222240 @default.
- W3217490912 cites W2088012387 @default.
- W3217490912 cites W2090521351 @default.
- W3217490912 cites W2092308204 @default.
- W3217490912 cites W2093277474 @default.