FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3217800628> ?p ?o ?g. }

• W3217800628 endingPage "10" @default.
• W3217800628 startingPage "306" @default.
• W3217800628 abstract "Abstract&#x0D; Background: It seems that parents’ consanguinity status effects the pattern of congenital heart defects (CHDs). In this study the CHD pattern in children with Down’s syndrome (DS) was determined in Afghanistan’s children population with a high consanguineous marriage rate and compared with historical cohorts from populations with low prevalence of parental consanguinity.&#x0D; Objective: This analytic cross sectional study aimed to determine the frequency and distribution of CHDs in Afghanistan children with Down’s Syndrome as a group in a community with a high consanguineous marriage rate and comparing these with different global studies and populations with low prevalence of consanguinity.&#x0D; Methods: This analytic cross sectional study was conducted in a pediatric teaching hospital in Kabul city - Afghanistan, named Maiwand Hospital. The subjects were all children with DS proven by clinical and cytogenetic study and referred to the pediatric cardiology service from September 2018–September 2020. Parents’ consanguinity was documented and 2D echocardiography and Doppler studies were performed by two experienced pediatric cardiologists after physical examination, ECG, and chest X-ray for each patient.&#x0D; Results: During the two-year study period, 120 DS patients were identified, 78 (65%) of whom had CHDs. The prevalence of isolated and multiple CHD in the 78 children with DS were 35% (42 patients) and 30% (36 patients), respectively. Ventricular septal defect (20.5%) and atrial septal defect (15.3%) were the most common isolated defects. The combination of VSD and PDA (20.5%) were the most frequent multiple CHDs. The most com­mon associations of CHD were VSD + PDA (20.5%) and VSD + ASD (10.2%). Consanguinity was found in 69.2 % of all parents.&#x0D; Conclusions: A higher frequency of CHD was documented in DS children from this population with a high consanguineous marriage rate. The frequencies of specific lesions were almost similar to those reported locally and internationally; VSD was the most frequently detected in this study. Interesting was the predominance of left-right shunt lesions and the relative rarity of cyanotic and complex CHD in this DS population.&#x0D; key words: congenital heart disease, atrioventricular septal defect, Down’s syndrome, trisomy 21, Afghanistan" @default.
• W3217800628 created "2021-12-06" @default.
• W3217800628 creator A5003809097 @default.
• W3217800628 creator A5016522419 @default.
• W3217800628 creator A5027553456 @default.
• W3217800628 creator A5040436882 @default.
• W3217800628 creator A5068201530 @default.
• W3217800628 date "2021-11-02" @default.
• W3217800628 modified "2023-09-23" @default.
• W3217800628 title "Parental consanguinity and congenital heart defects in Afghan children with Down’s syndrome" @default.
• W3217800628 cites W1521456530 @default.
• W3217800628 cites W165923286 @default.
• W3217800628 cites W19540508 @default.
• W3217800628 cites W1971780199 @default.
• W3217800628 cites W1973569098 @default.
• W3217800628 cites W1982041629 @default.
• W3217800628 cites W1995198589 @default.
• W3217800628 cites W1999229827 @default.
• W3217800628 cites W2011510371 @default.
• W3217800628 cites W2038175459 @default.
• W3217800628 cites W2040904496 @default.
• W3217800628 cites W2050259031 @default.
• W3217800628 cites W2057238401 @default.
• W3217800628 cites W2064979033 @default.
• W3217800628 cites W2085392953 @default.
• W3217800628 cites W2095227604 @default.
• W3217800628 cites W2152482827 @default.
• W3217800628 cites W2168031195 @default.
• W3217800628 cites W2170492641 @default.
• W3217800628 cites W2183485159 @default.
• W3217800628 cites W2257495759 @default.
• W3217800628 cites W4230599058 @default.
• W3217800628 cites W4361745143 @default.
• W3217800628 doi "https://doi.org/10.14238/pi61.6.2021.306-10" @default.
• W3217800628 hasPublicationYear "2021" @default.
• W3217800628 type Work @default.
• W3217800628 sameAs 3217800628 @default.
• W3217800628 citedByCount "0" @default.
• W3217800628 crossrefType "journal-article" @default.
• W3217800628 hasAuthorship W3217800628A5003809097 @default.
• W3217800628 hasAuthorship W3217800628A5016522419 @default.
• W3217800628 hasAuthorship W3217800628A5027553456 @default.
• W3217800628 hasAuthorship W3217800628A5040436882 @default.
• W3217800628 hasAuthorship W3217800628A5068201530 @default.
• W3217800628 hasBestOaLocation W32178006281 @default.
• W3217800628 hasConcept C118552586 @default.
• W3217800628 hasConcept C142052008 @default.
• W3217800628 hasConcept C142724271 @default.
• W3217800628 hasConcept C187212893 @default.
• W3217800628 hasConcept C2779923321 @default.
• W3217800628 hasConcept C2779954681 @default.
• W3217800628 hasConcept C2908647359 @default.
• W3217800628 hasConcept C2911029604 @default.
• W3217800628 hasConcept C71924100 @default.
• W3217800628 hasConcept C99454951 @default.
• W3217800628 hasConceptScore W3217800628C118552586 @default.
• W3217800628 hasConceptScore W3217800628C142052008 @default.
• W3217800628 hasConceptScore W3217800628C142724271 @default.
• W3217800628 hasConceptScore W3217800628C187212893 @default.
• W3217800628 hasConceptScore W3217800628C2779923321 @default.
• W3217800628 hasConceptScore W3217800628C2779954681 @default.
• W3217800628 hasConceptScore W3217800628C2908647359 @default.
• W3217800628 hasConceptScore W3217800628C2911029604 @default.
• W3217800628 hasConceptScore W3217800628C71924100 @default.
• W3217800628 hasConceptScore W3217800628C99454951 @default.
• W3217800628 hasIssue "6" @default.
• W3217800628 hasLocation W32178006281 @default.
• W3217800628 hasLocation W32178006282 @default.
• W3217800628 hasOpenAccess W3217800628 @default.
• W3217800628 hasPrimaryLocation W32178006281 @default.
• W3217800628 hasRelatedWork W1576709320 @default.
• W3217800628 hasRelatedWork W1968002162 @default.
• W3217800628 hasRelatedWork W2083786168 @default.
• W3217800628 hasRelatedWork W2084515301 @default.
• W3217800628 hasRelatedWork W2274831941 @default.
• W3217800628 hasRelatedWork W2400579116 @default.
• W3217800628 hasRelatedWork W2487833448 @default.
• W3217800628 hasRelatedWork W2613309834 @default.
• W3217800628 hasRelatedWork W3217800628 @default.
• W3217800628 hasRelatedWork W4223500682 @default.
• W3217800628 hasVolume "61" @default.
• W3217800628 isParatext "false" @default.
• W3217800628 isRetracted "false" @default.
• W3217800628 magId "3217800628" @default.
• W3217800628 workType "article" @default.