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• W322031617 abstract "Research Article1 December 1994free access Calcium-independent calmodulin requirement for endocytosis in yeast. E. Kübler E. Kübler Biozentrum University of Basel, Switzerland. Search for more papers by this author F. Schimmöller F. Schimmöller Biozentrum University of Basel, Switzerland. Search for more papers by this author H. Riezman H. Riezman Biozentrum University of Basel, Switzerland. Search for more papers by this author E. Kübler E. Kübler Biozentrum University of Basel, Switzerland. Search for more papers by this author F. Schimmöller F. Schimmöller Biozentrum University of Basel, Switzerland. Search for more papers by this author H. Riezman H. Riezman Biozentrum University of Basel, Switzerland. Search for more papers by this author Author Information E. Kübler1, F. Schimmöller1 and H. Riezman1 1Biozentrum University of Basel, Switzerland. The EMBO Journal (1994)13:5539-5546https://doi.org/10.1002/j.1460-2075.1994.tb06891.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info We have recently shown that actin and fimbrin are required for the internalization step of endocytosis in yeast. Using a yeast strain with a temperature-sensitive allele of CMD1, encoding calmodulin, we demonstrate that this protein is also required for this process. Calmodulin mutants that have lost their high-affinity calcium binding sites are, however, able to carry out endocytosis normally. A mutation in Myo2p, an unconventional myosin that is a possible target of calmodulin, did not inhibit endocytosis. The function of calmodulin in endocytosis seems to be specific among membrane trafficking events, because the calmodulin mutants are not defective for biogenesis of soluble vacuolar hydrolases nor invertase secretion. Calmodulin does not seem to play a major role in the post-internalization steps of the endocytic pathway in yeast. Previous ArticleNext Article Volume 13Issue 231 December 1994In this issue RelatedDetailsLoading ..." @default.
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• W322031617 title "Calcium-independent calmodulin requirement for endocytosis in yeast." @default.
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