FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W322116502> ?p ?o ?g. }

• W322116502 endingPage "9" @default.
• W322116502 startingPage "481" @default.
• W322116502 abstract "As part of a study designed to reveal information about molecular features of allergenic food proteins after absorption from the gut the specificity of antibodies in normal human serum to hen's egg ovalbumin was investigated using ELISA techniques. Preliminary investigations with monoclonal antibodies and hyperimmune rabbit antiserum specific for ovalbumin in its native and denatured form established that the molecule underwent an extensive conformational change on adsorption to polyvinyl chloride microtitre plates. The native conformation could be retained by using antibodies to couple the protein to the surface. Serum from 90% of healthy adult human donors contained IgG antibodies to ovalbumin. In nearly all cases the antibodies were specific predominantly for the native molecule and could not be absorbed with denatured ovalbumin or peptides prepared from it by cleavage with cyanogen bromide or trypsin. Antibodies to denatured ovalbumin were detected in most sera but at very low levels and were preferentially absorbed by the homologous antigen; peptides and native ovalbumin showing variable absorptive activity. Thus, although ovalbumin is ingested largely in a denatured form, the serum antibody response is stimulated mainly by topographic epitopes of the native molecule." @default.
• W322116502 created "2016-06-24" @default.
• W322116502 creator A5014990865 @default.
• W322116502 creator A5046163569 @default.
• W322116502 creator A5049998019 @default.
• W322116502 creator A5082117837 @default.
• W322116502 date "1986-11-01" @default.
• W322116502 modified "2023-09-27" @default.
• W322116502 title "Studies on the specificity of antibodies to ovalbumin in normal human serum: technical considerations in the use of ELISA methods." @default.
• W322116502 cites W1577538717 @default.
• W322116502 cites W1969196879 @default.
• W322116502 cites W1979447036 @default.
• W322116502 cites W1982843775 @default.
• W322116502 cites W1986222846 @default.
• W322116502 cites W1998831848 @default.
• W322116502 cites W2000778866 @default.
• W322116502 cites W2010052656 @default.
• W322116502 cites W2015727718 @default.
• W322116502 cites W2023430392 @default.
• W322116502 cites W2032594229 @default.
• W322116502 cites W2032715998 @default.
• W322116502 cites W2037852696 @default.
• W322116502 cites W2038771468 @default.
• W322116502 cites W2072373468 @default.
• W322116502 cites W2099174374 @default.
• W322116502 cites W2195018353 @default.
• W322116502 cites W2331143404 @default.
• W322116502 cites W3096319199 @default.
• W322116502 cites W53070584 @default.
• W322116502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1542523" @default.
• W322116502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3815902" @default.
• W322116502 hasPublicationYear "1986" @default.
• W322116502 type Work @default.
• W322116502 sameAs 322116502 @default.
• W322116502 citedByCount "13" @default.
• W322116502 countsByYear W3221165022012 @default.
• W322116502 countsByYear W3221165022017 @default.
• W322116502 countsByYear W3221165022018 @default.
• W322116502 countsByYear W3221165022022 @default.
• W322116502 countsByYear W3221165022023 @default.
• W322116502 crossrefType "journal-article" @default.
• W322116502 hasAuthorship W322116502A5014990865 @default.
• W322116502 hasAuthorship W322116502A5046163569 @default.
• W322116502 hasAuthorship W322116502A5049998019 @default.
• W322116502 hasAuthorship W322116502A5082117837 @default.
• W322116502 hasConcept C104317684 @default.
• W322116502 hasConcept C147483822 @default.
• W322116502 hasConcept C153911025 @default.
• W322116502 hasConcept C159654299 @default.
• W322116502 hasConcept C167625842 @default.
• W322116502 hasConcept C181199279 @default.
• W322116502 hasConcept C185592680 @default.
• W322116502 hasConcept C195616568 @default.
• W322116502 hasConcept C203014093 @default.
• W322116502 hasConcept C2776946954 @default.
• W322116502 hasConcept C2777093645 @default.
• W322116502 hasConcept C2778484053 @default.
• W322116502 hasConcept C2778597219 @default.
• W322116502 hasConcept C2779026604 @default.
• W322116502 hasConcept C2780340462 @default.
• W322116502 hasConcept C2780632150 @default.
• W322116502 hasConcept C542903549 @default.
• W322116502 hasConcept C55493867 @default.
• W322116502 hasConcept C86803240 @default.
• W322116502 hasConcept C91523082 @default.
• W322116502 hasConceptScore W322116502C104317684 @default.
• W322116502 hasConceptScore W322116502C147483822 @default.
• W322116502 hasConceptScore W322116502C153911025 @default.
• W322116502 hasConceptScore W322116502C159654299 @default.
• W322116502 hasConceptScore W322116502C167625842 @default.
• W322116502 hasConceptScore W322116502C181199279 @default.
• W322116502 hasConceptScore W322116502C185592680 @default.
• W322116502 hasConceptScore W322116502C195616568 @default.
• W322116502 hasConceptScore W322116502C203014093 @default.
• W322116502 hasConceptScore W322116502C2776946954 @default.
• W322116502 hasConceptScore W322116502C2777093645 @default.
• W322116502 hasConceptScore W322116502C2778484053 @default.
• W322116502 hasConceptScore W322116502C2778597219 @default.
• W322116502 hasConceptScore W322116502C2779026604 @default.
• W322116502 hasConceptScore W322116502C2780340462 @default.
• W322116502 hasConceptScore W322116502C2780632150 @default.
• W322116502 hasConceptScore W322116502C542903549 @default.
• W322116502 hasConceptScore W322116502C55493867 @default.
• W322116502 hasConceptScore W322116502C86803240 @default.
• W322116502 hasConceptScore W322116502C91523082 @default.
• W322116502 hasIssue "2" @default.
• W322116502 hasLocation W3221165021 @default.
• W322116502 hasOpenAccess W322116502 @default.
• W322116502 hasPrimaryLocation W3221165021 @default.
• W322116502 hasRelatedWork W1604248381 @default.
• W322116502 hasRelatedWork W1997001434 @default.
• W322116502 hasRelatedWork W2057268039 @default.
• W322116502 hasRelatedWork W2057492984 @default.
• W322116502 hasRelatedWork W2057918160 @default.
• W322116502 hasRelatedWork W2069235615 @default.
• W322116502 hasRelatedWork W2146940419 @default.
• W322116502 hasRelatedWork W2170937824 @default.
• W322116502 hasRelatedWork W2409024641 @default.

• next