Matches in SemOpenAlex for { <https://semopenalex.org/work/W32236305> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W32236305 endingPage "120" @default.
- W32236305 startingPage "115" @default.
- W32236305 abstract "Background. Facilitation therapy in ST-elevation myocardial infarction (STEMI) is still controversial and no relationship between timing of treatment and efficacy has been reported to date. Methods. In order to evaluate the effect of pre-catheterization laboratory (cath lab) administration of eptifibatide on pre-percutaneous coronary intervention (PCI) thrombolysis in myocardial infarction (TIMI) flow and its correlation with ischemia duration, we studied all 438 STEMI patients treated with primary PCI from January 2006 to December 2007: 310 patients were pretreated with eptifibatide (Group P), while 128 patients received either no glycoprotein IIb/IIIa inhibitors or were only given them in the cath lab (Group C). All ischemia times (chest pain onset, diagnostic electrocardiogram, eptifibatide administration, cath lab arrival, first balloon inflation) were recorded. Group P was divided into early (E: 159 patients with symptoms duration s 90 minutes, and late (L: 151 patients) subgroups. Pre- and post-PCI TIMI grade flow, and 30-day outcomes were recorded. Results. At angiography, TIMI grade 2 or 3 flow was observed in 54% of cases in Group P vs. 34% in Group C (p < 0.001), and in 64% vs. 44% in E and L subgroups, respectively (p < 0.001). In Group P, there was a strong correlation between pre-PCI TIMI flow and timing of eptifibatide administration. Pretreatment with eptifibatide and symptom duration of s 90 minutes resulted in independent predictors of pre-PCI TIMI ≥ 2 flow on multivariable analysis. Thirty-day mortality was 1.9% in Group P and 9.5% in Group C (p < 0.001). Conclusions. In our experience, very early (< 90 minutes) eptifibatide therapy prior to primary PCI achieves a higher rate of pre-PCI TIMI flow a 2 with respect to late administration." @default.
- W32236305 created "2016-06-24" @default.
- W32236305 creator A5005576877 @default.
- W32236305 creator A5038624332 @default.
- W32236305 creator A5048076324 @default.
- W32236305 creator A5066992130 @default.
- W32236305 creator A5072153462 @default.
- W32236305 creator A5085183706 @default.
- W32236305 date "2009-03-01" @default.
- W32236305 modified "2023-09-24" @default.
- W32236305 title "Administration of eptifibatide during transfer for primary PCI in patients with STEMI: effect on Pre-PCI TIMI flow and its correlation with pain-to-therapy time." @default.
- W32236305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19258642" @default.
- W32236305 hasPublicationYear "2009" @default.
- W32236305 type Work @default.
- W32236305 sameAs 32236305 @default.
- W32236305 citedByCount "1" @default.
- W32236305 countsByYear W322363052014 @default.
- W32236305 crossrefType "journal-article" @default.
- W32236305 hasAuthorship W32236305A5005576877 @default.
- W32236305 hasAuthorship W32236305A5038624332 @default.
- W32236305 hasAuthorship W32236305A5048076324 @default.
- W32236305 hasAuthorship W32236305A5066992130 @default.
- W32236305 hasAuthorship W32236305A5072153462 @default.
- W32236305 hasAuthorship W32236305A5085183706 @default.
- W32236305 hasConcept C126322002 @default.
- W32236305 hasConcept C164705383 @default.
- W32236305 hasConcept C2776239313 @default.
- W32236305 hasConcept C2776335557 @default.
- W32236305 hasConcept C2777628954 @default.
- W32236305 hasConcept C2777849778 @default.
- W32236305 hasConcept C2777995511 @default.
- W32236305 hasConcept C2778704086 @default.
- W32236305 hasConcept C2779581417 @default.
- W32236305 hasConcept C2780400711 @default.
- W32236305 hasConcept C2781056559 @default.
- W32236305 hasConcept C42219234 @default.
- W32236305 hasConcept C45393284 @default.
- W32236305 hasConcept C500558357 @default.
- W32236305 hasConcept C71924100 @default.
- W32236305 hasConceptScore W32236305C126322002 @default.
- W32236305 hasConceptScore W32236305C164705383 @default.
- W32236305 hasConceptScore W32236305C2776239313 @default.
- W32236305 hasConceptScore W32236305C2776335557 @default.
- W32236305 hasConceptScore W32236305C2777628954 @default.
- W32236305 hasConceptScore W32236305C2777849778 @default.
- W32236305 hasConceptScore W32236305C2777995511 @default.
- W32236305 hasConceptScore W32236305C2778704086 @default.
- W32236305 hasConceptScore W32236305C2779581417 @default.
- W32236305 hasConceptScore W32236305C2780400711 @default.
- W32236305 hasConceptScore W32236305C2781056559 @default.
- W32236305 hasConceptScore W32236305C42219234 @default.
- W32236305 hasConceptScore W32236305C45393284 @default.
- W32236305 hasConceptScore W32236305C500558357 @default.
- W32236305 hasConceptScore W32236305C71924100 @default.
- W32236305 hasIssue "3" @default.
- W32236305 hasLocation W322363051 @default.
- W32236305 hasLocation W322363052 @default.
- W32236305 hasOpenAccess W32236305 @default.
- W32236305 hasPrimaryLocation W322363051 @default.
- W32236305 hasRelatedWork W1990310374 @default.
- W32236305 hasRelatedWork W1998261320 @default.
- W32236305 hasRelatedWork W2037271106 @default.
- W32236305 hasRelatedWork W2112925618 @default.
- W32236305 hasRelatedWork W2146028119 @default.
- W32236305 hasRelatedWork W2328264667 @default.
- W32236305 hasRelatedWork W2353337575 @default.
- W32236305 hasRelatedWork W2357284701 @default.
- W32236305 hasRelatedWork W2358122555 @default.
- W32236305 hasRelatedWork W2368457192 @default.
- W32236305 hasRelatedWork W2380861129 @default.
- W32236305 hasRelatedWork W2383233802 @default.
- W32236305 hasRelatedWork W2383438139 @default.
- W32236305 hasRelatedWork W2384412731 @default.
- W32236305 hasRelatedWork W2384519520 @default.
- W32236305 hasRelatedWork W2388167333 @default.
- W32236305 hasRelatedWork W2409965891 @default.
- W32236305 hasRelatedWork W3031155054 @default.
- W32236305 hasRelatedWork W3031376217 @default.
- W32236305 hasRelatedWork W44749406 @default.
- W32236305 hasVolume "21" @default.
- W32236305 isParatext "false" @default.
- W32236305 isRetracted "false" @default.
- W32236305 magId "32236305" @default.
- W32236305 workType "article" @default.