Matches in SemOpenAlex for { <https://semopenalex.org/work/W323727352> ?p ?o ?g. }
- W323727352 endingPage "9" @default.
- W323727352 startingPage "3" @default.
- W323727352 abstract "Studies initially focused on understanding the hormonal regulation of milk protein gene expression have evolved using transgenic and knockout mouse models to help provide new insights into the mechanisms by which hormones regulate proliferation during normal mammary gland development, and how these regulatory mechanisms have deviated in breast cancer progression. During normal mammary development, a non-uniform pattern of expression of the estrogen receptor alpha, and the progesterone and the prolactin receptors in the ductal epithelium is established. All of these receptors apparently are co-expressed in non-proliferating ductal epithelial cells. Local growth factors, which are members of the Wnt, EGF and IGF families and Rank ligand, act as mediators of systemic steroid and lactogenic hormones to stimulate proliferation of adjacent ductal epithelial cells via a paracrine mechanism. During early breast cancer progression a more uniform pattern of steroid receptor expression is observed accompanied by an apparent switch to an autocrine mechanism regulating cell proliferation." @default.
- W323727352 created "2016-06-24" @default.
- W323727352 creator A5086412465 @default.
- W323727352 date "2003-12-01" @default.
- W323727352 modified "2023-10-16" @default.
- W323727352 title "Hormone Receptor Patterning Plays a Critical Role in Normal Lobuloalveolar Development and Breast Cancer Progression" @default.
- W323727352 cites W1548774328 @default.
- W323727352 cites W1574410335 @default.
- W323727352 cites W1597303621 @default.
- W323727352 cites W1635738393 @default.
- W323727352 cites W1706037773 @default.
- W323727352 cites W1882868104 @default.
- W323727352 cites W1970078194 @default.
- W323727352 cites W1972810033 @default.
- W323727352 cites W1973370838 @default.
- W323727352 cites W1976079453 @default.
- W323727352 cites W1977872674 @default.
- W323727352 cites W2000557258 @default.
- W323727352 cites W2001943366 @default.
- W323727352 cites W2011381245 @default.
- W323727352 cites W2011612270 @default.
- W323727352 cites W2014620140 @default.
- W323727352 cites W2021864884 @default.
- W323727352 cites W2033132112 @default.
- W323727352 cites W2035847457 @default.
- W323727352 cites W2036098607 @default.
- W323727352 cites W2036638605 @default.
- W323727352 cites W2037742127 @default.
- W323727352 cites W2038425754 @default.
- W323727352 cites W2041354540 @default.
- W323727352 cites W2042191722 @default.
- W323727352 cites W2042619286 @default.
- W323727352 cites W2051320963 @default.
- W323727352 cites W2052768254 @default.
- W323727352 cites W2058705034 @default.
- W323727352 cites W2079891977 @default.
- W323727352 cites W2082559087 @default.
- W323727352 cites W2087027920 @default.
- W323727352 cites W2091005988 @default.
- W323727352 cites W2091955415 @default.
- W323727352 cites W2094836768 @default.
- W323727352 cites W2098974513 @default.
- W323727352 cites W2108219444 @default.
- W323727352 cites W2113020166 @default.
- W323727352 cites W2120352430 @default.
- W323727352 cites W2120653485 @default.
- W323727352 cites W2123637362 @default.
- W323727352 cites W2134506331 @default.
- W323727352 cites W2135722286 @default.
- W323727352 cites W2142800313 @default.
- W323727352 cites W2143633028 @default.
- W323727352 cites W2149120477 @default.
- W323727352 cites W2155549511 @default.
- W323727352 cites W2158029937 @default.
- W323727352 cites W2167683695 @default.
- W323727352 cites W2415529588 @default.
- W323727352 cites W80320258 @default.
- W323727352 doi "https://doi.org/10.3233/bd-2003-18102" @default.
- W323727352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15687684" @default.
- W323727352 hasPublicationYear "2003" @default.
- W323727352 type Work @default.
- W323727352 sameAs 323727352 @default.
- W323727352 citedByCount "33" @default.
- W323727352 countsByYear W3237273522012 @default.
- W323727352 countsByYear W3237273522013 @default.
- W323727352 countsByYear W3237273522014 @default.
- W323727352 countsByYear W3237273522015 @default.
- W323727352 countsByYear W3237273522016 @default.
- W323727352 countsByYear W3237273522019 @default.
- W323727352 countsByYear W3237273522020 @default.
- W323727352 countsByYear W3237273522021 @default.
- W323727352 countsByYear W3237273522022 @default.
- W323727352 crossrefType "journal-article" @default.
- W323727352 hasAuthorship W323727352A5086412465 @default.
- W323727352 hasConcept C121608353 @default.
- W323727352 hasConcept C126322002 @default.
- W323727352 hasConcept C128240485 @default.
- W323727352 hasConcept C134018914 @default.
- W323727352 hasConcept C137620995 @default.
- W323727352 hasConcept C170493617 @default.
- W323727352 hasConcept C2776880931 @default.
- W323727352 hasConcept C2778001805 @default.
- W323727352 hasConcept C502942594 @default.
- W323727352 hasConcept C530470458 @default.
- W323727352 hasConcept C62478195 @default.
- W323727352 hasConcept C71315377 @default.
- W323727352 hasConcept C71924100 @default.
- W323727352 hasConcept C7876069 @default.
- W323727352 hasConcept C84606932 @default.
- W323727352 hasConcept C86803240 @default.
- W323727352 hasConcept C95444343 @default.
- W323727352 hasConceptScore W323727352C121608353 @default.
- W323727352 hasConceptScore W323727352C126322002 @default.
- W323727352 hasConceptScore W323727352C128240485 @default.
- W323727352 hasConceptScore W323727352C134018914 @default.
- W323727352 hasConceptScore W323727352C137620995 @default.
- W323727352 hasConceptScore W323727352C170493617 @default.
- W323727352 hasConceptScore W323727352C2776880931 @default.