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- W325524838 abstract "Publisher Summary This chapter provides an overview of synaptic fine structure and neural dynamics. It discusses the organization of the presynaptic area and the problem of membrane subunits vesting the synaptic cleft. The chapter presents the electron microscopic investigations of synaptic structures that were undertaken on material prepared with conventional and with a new bismuth-iodide staining method. These investigations gave special attention to the structural organization of the presynaptic grid and the problem of its functional interaction with synaptic vesicles, clear and dark cored. The latter may be involved in transport functions from the perikaryon to the nerve endings and provide the dense projections of the presynaptic grid with important constituents. A so-called iodophilic layer was found on both sides of the synaptic membrane. It seems to form a paired subunit in the cleft. Its absence from the region of the holes of the presynaptic grid and its accentuation within the synaptic cleft raise problems of functional interpretations." @default.
- W325524838 created "2016-06-24" @default.
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- W325524838 date "1969-01-01" @default.
- W325524838 modified "2023-10-16" @default.
- W325524838 title "SYNAPTIC FINE STRUCTURE AND NEURAL DYNAMICS**Supported by Grant No. 4356 of the Swiss National Foundation for Scientific Research." @default.
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- W325524838 doi "https://doi.org/10.1016/b978-0-12-611908-4.50018-6" @default.
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