FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W326968443> ?p ?o ?g. }

• W326968443 endingPage "345" @default.
• W326968443 startingPage "335" @default.
• W326968443 abstract "Recent behavioural and neurophysiological studies suggest that the hippocampus uses vestibular information, along with information from other sensory systems, to accomplish its spatial computational processing. By contrast, there is a dearth of neurochemical data on the interactions between the vestibular system and hippocampus. The aim of the present study was to examine levels of glutamine, glutamate, gamma-amino-butyric acid (GABA), glycine, serine, threonine and taurine in the CA1, CA2, CA3 and dentate gyrus (DG) subregions of the hippocampus at 10 hs following UVD in guinea pig, using high-performance liquid chromatography (HPLC) with electrochemical detection (ECD). Glutamine levels were not significantly different between the UVD and control conditions, except in the bilateral DG where they were significantly lower (p < 0.05). However, no significant differences in glutamate levels were observed. Although there were no significant differences in GABA levels in the DG, CA1 and CA2 regions following UVD, there was a significant increase in GABA levels in the contralateral CA3 region in the sham group compared to intact anesthetic controls. Glycine levels were significantly higher in the contralateral DG and ipsilateral CA1 in the sham groups compared to intact anesthetic controls (p < 0.05). However, in contralateral CA2 and ipsilateral CA3, glycine levels were significantly higher for both the sham and UVD groups compared to anesthetic controls (p < 0.05). Threonine levels were not significantly different in CA1; however, in ipsilateral DG and ipsilateral CA3, they were significantly higher in the sham groups compared to anesthetic controls and the UVD groups (p < 0.05). In ipsilateral CA2, threonine levels were significantly higher in the UVD group compared to anesthetic controls (p < 0.05). Taurine levels did not differ significantly in the DG, CA1 or CA3 following UVD; however, they were significantly higher in ipsilateral CA2 following UVD (p < 0.05). Finally, serine levels were not significantly different in any area of the hippocampus following UVD or sham surgery. This study provides the first data on amino acid levels in the hippocampus following UVD and sham temporal bone surgery and suggests that peripheral vestibular damage may particularly affect glutamine, glycine, threonine and taurine levels in various subregions of the hippocampus." @default.
• W326968443 created "2016-06-24" @default.
• W326968443 creator A5011234391 @default.
• W326968443 creator A5043560927 @default.
• W326968443 creator A5090982433 @default.
• W326968443 date "1999-10-01" @default.
• W326968443 modified "2023-09-27" @default.
• W326968443 title "Subregional analysis of amino acid levels in the guinea pig hippocampus following unilateral vestibular deafferentation" @default.
• W326968443 doi "https://doi.org/10.3233/ves-1999-9503" @default.
• W326968443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10544372" @default.
• W326968443 hasPublicationYear "1999" @default.
• W326968443 type Work @default.
• W326968443 sameAs 326968443 @default.
• W326968443 citedByCount "10" @default.
• W326968443 countsByYear W3269684432013 @default.
• W326968443 countsByYear W3269684432017 @default.
• W326968443 countsByYear W3269684432020 @default.
• W326968443 crossrefType "journal-article" @default.
• W326968443 hasAuthorship W326968443A5011234391 @default.
• W326968443 hasAuthorship W326968443A5043560927 @default.
• W326968443 hasAuthorship W326968443A5090982433 @default.
• W326968443 hasConcept C126322002 @default.
• W326968443 hasConcept C134018914 @default.
• W326968443 hasConcept C169760540 @default.
• W326968443 hasConcept C170493617 @default.
• W326968443 hasConcept C185592680 @default.
• W326968443 hasConcept C190041318 @default.
• W326968443 hasConcept C2776464000 @default.
• W326968443 hasConcept C2777756961 @default.
• W326968443 hasConcept C2778162923 @default.
• W326968443 hasConcept C2778421575 @default.
• W326968443 hasConcept C2779349466 @default.
• W326968443 hasConcept C2779701627 @default.
• W326968443 hasConcept C2781161787 @default.
• W326968443 hasConcept C42219234 @default.
• W326968443 hasConcept C515207424 @default.
• W326968443 hasConcept C55493867 @default.
• W326968443 hasConcept C61174792 @default.
• W326968443 hasConcept C71924100 @default.
• W326968443 hasConcept C86803240 @default.
• W326968443 hasConceptScore W326968443C126322002 @default.
• W326968443 hasConceptScore W326968443C134018914 @default.
• W326968443 hasConceptScore W326968443C169760540 @default.
• W326968443 hasConceptScore W326968443C170493617 @default.
• W326968443 hasConceptScore W326968443C185592680 @default.
• W326968443 hasConceptScore W326968443C190041318 @default.
• W326968443 hasConceptScore W326968443C2776464000 @default.
• W326968443 hasConceptScore W326968443C2777756961 @default.
• W326968443 hasConceptScore W326968443C2778162923 @default.
• W326968443 hasConceptScore W326968443C2778421575 @default.
• W326968443 hasConceptScore W326968443C2779349466 @default.
• W326968443 hasConceptScore W326968443C2779701627 @default.
• W326968443 hasConceptScore W326968443C2781161787 @default.
• W326968443 hasConceptScore W326968443C42219234 @default.
• W326968443 hasConceptScore W326968443C515207424 @default.
• W326968443 hasConceptScore W326968443C55493867 @default.
• W326968443 hasConceptScore W326968443C61174792 @default.
• W326968443 hasConceptScore W326968443C71924100 @default.
• W326968443 hasConceptScore W326968443C86803240 @default.
• W326968443 hasIssue "5" @default.
• W326968443 hasLocation W3269684431 @default.
• W326968443 hasLocation W3269684432 @default.
• W326968443 hasOpenAccess W326968443 @default.
• W326968443 hasPrimaryLocation W3269684431 @default.
• W326968443 hasRelatedWork W2009410328 @default.
• W326968443 hasRelatedWork W2013730397 @default.
• W326968443 hasRelatedWork W2046960488 @default.
• W326968443 hasRelatedWork W2049748437 @default.
• W326968443 hasRelatedWork W2061769920 @default.
• W326968443 hasRelatedWork W2340676451 @default.
• W326968443 hasRelatedWork W2384851497 @default.
• W326968443 hasRelatedWork W2469191932 @default.
• W326968443 hasRelatedWork W260147576 @default.
• W326968443 hasRelatedWork W4851348 @default.
• W326968443 hasVolume "9" @default.
• W326968443 isParatext "false" @default.
• W326968443 isRetracted "false" @default.
• W326968443 magId "326968443" @default.
• W326968443 workType "article" @default.