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- W328240141 abstract "This chapter describes treatment planning optimization in brachytherapy and the design of a clinical decision support system. Brachytherapy refers to the placement of radioactive sources (seeds) inside a tumor site. The fundamental problem in treatment planning for brachytherapy is to determine where to place sources so as to deliver a sufficient radiation dose to kill the cancer, while limiting exposure of healthy tissue. We first present the sequence of steps that are involved in brachytherapy treatment planning. State-of-the-art mixed integer programming models are then described and some algorithmic approaches are outlined. The automated clinical decision support system allows for real-time generation of optimal seed configurations using ultrasound images acquired prior to seed implantation, and dynamic dose correction during the implantation process." @default.
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- W328240141 date "2006-04-04" @default.
- W328240141 modified "2023-10-14" @default.
- W328240141 title "Optimization and Decision Support in Brachytherapy Treatment Planning" @default.
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- W328240141 doi "https://doi.org/10.1007/1-4020-8066-2_28" @default.
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