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- W32837384 abstract "About 35 years after the first in vitro studies of the insulin receptor, considerable progress has been accomplished in the structural biology of the insulin-receptor interaction, and of the receptor tyrosine kinase family in general. This brief review attempts to assemble the various pieces of the puzzle, despite the lack of a detailed crystallographic structure of the insulin-receptor complex, and to establish a model that explains the mechanism of receptor activation, its negative cooperativity, and the triggering of intracellular signalling pathways." @default.
- W32837384 created "2016-06-24" @default.
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- W32837384 date "2005-07-23" @default.
- W32837384 modified "2023-09-23" @default.
- W32837384 title "[The insuline receptor: structure and function]." @default.
- W32837384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16035282" @default.
- W32837384 hasPublicationYear "2005" @default.
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