Matches in SemOpenAlex for { <https://semopenalex.org/work/W329103681> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W329103681 endingPage "7" @default.
- W329103681 startingPage "1901" @default.
- W329103681 abstract "Intraepidermal neutrophilic IgA dermatosis, a rare skin disease entity manifested with blisters and pustules clinically and lower epidermal blister, acantholysis, and neutrophilic infiltration pathologically, was first reported in 1985. Although the disease is characterized by IgA autoantibodies targeting the epithelial cell surface component, the target antigen has not been determined. We investigated a patient with this disease by histopathology, direct and indirect immunofluorescence, immunoblotting, and immunoadsorption studies. The pustular lesion was characterized by blister at the lower epidermis, acantholysis, and neutrophilic infiltration. Nonsecretory IgA1 subclass autoantibodies targeting the lower epithelial cell surfaces were detected in the patient's skin and serum. The patient's IgA autoantibodies labeled a recombinant desmosomal protein desmoglein 3 on immunoblotting and the immunolabeling of epithelial cell surfaces was eliminated by preadsorption with desmoglein 3. Thus, desmoglein 3 is identified as a target antigen in intraepidermal neutrophilic IgA dermatosis. The ability of IgA1 autoantibodies to bind neutrophils may be responsible for the prominent neutrophilic infiltration observed histopathologically and for the pustular lesions observed clinically." @default.
- W329103681 created "2016-06-24" @default.
- W329103681 creator A5001311911 @default.
- W329103681 creator A5007473761 @default.
- W329103681 creator A5007855326 @default.
- W329103681 creator A5029921699 @default.
- W329103681 creator A5030763743 @default.
- W329103681 creator A5046643472 @default.
- W329103681 date "1997-06-01" @default.
- W329103681 modified "2023-10-16" @default.
- W329103681 title "Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis." @default.
- W329103681 cites W1541995708 @default.
- W329103681 cites W1542650808 @default.
- W329103681 cites W1971624923 @default.
- W329103681 cites W1976739389 @default.
- W329103681 cites W1984915036 @default.
- W329103681 cites W1991063758 @default.
- W329103681 cites W2005777684 @default.
- W329103681 cites W2008638671 @default.
- W329103681 cites W2016635164 @default.
- W329103681 cites W2018155538 @default.
- W329103681 cites W2018289835 @default.
- W329103681 cites W2018379254 @default.
- W329103681 cites W2035135968 @default.
- W329103681 cites W2040723234 @default.
- W329103681 cites W2051213206 @default.
- W329103681 cites W2055386268 @default.
- W329103681 cites W2060034838 @default.
- W329103681 cites W2070870690 @default.
- W329103681 cites W2078623154 @default.
- W329103681 cites W2094800200 @default.
- W329103681 cites W2100837269 @default.
- W329103681 cites W2138252938 @default.
- W329103681 cites W2138270253 @default.
- W329103681 cites W2139887355 @default.
- W329103681 cites W2157124714 @default.
- W329103681 cites W2416130586 @default.
- W329103681 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1858303" @default.
- W329103681 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9176383" @default.
- W329103681 hasPublicationYear "1997" @default.
- W329103681 type Work @default.
- W329103681 sameAs 329103681 @default.
- W329103681 citedByCount "15" @default.
- W329103681 countsByYear W3291036812014 @default.
- W329103681 crossrefType "journal-article" @default.
- W329103681 hasAuthorship W329103681A5001311911 @default.
- W329103681 hasAuthorship W329103681A5007473761 @default.
- W329103681 hasAuthorship W329103681A5007855326 @default.
- W329103681 hasAuthorship W329103681A5029921699 @default.
- W329103681 hasAuthorship W329103681A5030763743 @default.
- W329103681 hasAuthorship W329103681A5046643472 @default.
- W329103681 hasConcept C121332964 @default.
- W329103681 hasConcept C142724271 @default.
- W329103681 hasConcept C153400128 @default.
- W329103681 hasConcept C159654299 @default.
- W329103681 hasConcept C163764329 @default.
- W329103681 hasConcept C203014093 @default.
- W329103681 hasConcept C2778862538 @default.
- W329103681 hasConcept C2780684067 @default.
- W329103681 hasConcept C2781327288 @default.
- W329103681 hasConcept C2909223747 @default.
- W329103681 hasConcept C2910519024 @default.
- W329103681 hasConcept C67326383 @default.
- W329103681 hasConcept C71924100 @default.
- W329103681 hasConcept C97355855 @default.
- W329103681 hasConceptScore W329103681C121332964 @default.
- W329103681 hasConceptScore W329103681C142724271 @default.
- W329103681 hasConceptScore W329103681C153400128 @default.
- W329103681 hasConceptScore W329103681C159654299 @default.
- W329103681 hasConceptScore W329103681C163764329 @default.
- W329103681 hasConceptScore W329103681C203014093 @default.
- W329103681 hasConceptScore W329103681C2778862538 @default.
- W329103681 hasConceptScore W329103681C2780684067 @default.
- W329103681 hasConceptScore W329103681C2781327288 @default.
- W329103681 hasConceptScore W329103681C2909223747 @default.
- W329103681 hasConceptScore W329103681C2910519024 @default.
- W329103681 hasConceptScore W329103681C67326383 @default.
- W329103681 hasConceptScore W329103681C71924100 @default.
- W329103681 hasConceptScore W329103681C97355855 @default.
- W329103681 hasIssue "6" @default.
- W329103681 hasLocation W3291036811 @default.
- W329103681 hasOpenAccess W329103681 @default.
- W329103681 hasPrimaryLocation W3291036811 @default.
- W329103681 hasRelatedWork W112917578 @default.
- W329103681 hasRelatedWork W1511359938 @default.
- W329103681 hasRelatedWork W1990334258 @default.
- W329103681 hasRelatedWork W2054999144 @default.
- W329103681 hasRelatedWork W2111608824 @default.
- W329103681 hasRelatedWork W2397113684 @default.
- W329103681 hasRelatedWork W252029681 @default.
- W329103681 hasRelatedWork W2588329979 @default.
- W329103681 hasRelatedWork W3193081148 @default.
- W329103681 hasRelatedWork W4205378647 @default.
- W329103681 hasVolume "150" @default.
- W329103681 isParatext "false" @default.
- W329103681 isRetracted "false" @default.
- W329103681 magId "329103681" @default.
- W329103681 workType "article" @default.