FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W329750957> ?p ?o ?g. }

• W329750957 endingPage "1585" @default.
• W329750957 startingPage "1579" @default.
• W329750957 abstract "Abstract Marrow cells from mice lacking high-affinity receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF; βc−/− mice) were shown to bind and internalize much less GM-CSF than cells from normal (βc+/+) mice. βc−/− mice were used to determine the effect of negligible receptor-mediated clearance on detectible GM-CSF responses to the intravenous injection of endotoxin or the intraperitoneal injection of casein plus microorganisms. Unlike the minor serum GM-CSF responses to endotoxin seen in βc+/+ mice, serum GM-CSF levels rose 30-fold to 9 ng/mL in βc−/− mice even though loss of GM-CSF in the urine was greater than in βc+/+ mice. Organs from βc−/− and βc+/+ mice had a similar capacity to produce GM-CSF in vitro, as did peritoneal cells from both types of mice when challenged in vitro by casein. However, when casein was injected intraperitoneally, βc−/− mice developed higher and more sustained levels of GM-CSF than did βc+/+ mice. The data indicated that receptor-dependent removal of GM-CSF masks the magnitude of GM-CSF responses to endotoxin and local infections. Because of this phenomenon, serum GM-CSF concentrations can be a misleading index of the occurrence or nonoccurrence of GM-CSF responses to infections." @default.
• W329750957 created "2016-06-24" @default.
• W329750957 creator A5034221146 @default.
• W329750957 creator A5034450243 @default.
• W329750957 creator A5037049833 @default.
• W329750957 creator A5069357139 @default.
• W329750957 date "1999-03-01" @default.
• W329750957 modified "2023-09-29" @default.
• W329750957 title "Receptor Clearance Obscures the Magnitude of Granulocyte-Macrophage Colony-Stimulating Factor Responses in Mice to Endotoxin or Local Infections" @default.
• W329750957 cites W12954242 @default.
• W329750957 cites W1542699852 @default.
• W329750957 cites W1906900122 @default.
• W329750957 cites W1985347885 @default.
• W329750957 cites W1989037479 @default.
• W329750957 cites W2030697288 @default.
• W329750957 cites W2031250623 @default.
• W329750957 cites W2041484950 @default.
• W329750957 cites W2052068396 @default.
• W329750957 cites W2062042301 @default.
• W329750957 cites W2072602135 @default.
• W329750957 cites W2073894431 @default.
• W329750957 cites W2132982096 @default.
• W329750957 cites W2270245312 @default.
• W329750957 cites W2297816223 @default.
• W329750957 cites W2895726587 @default.
• W329750957 cites W29651041 @default.
• W329750957 cites W4245648471 @default.
• W329750957 doi "https://doi.org/10.1182/blood.v93.5.1579" @default.
• W329750957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10029586" @default.
• W329750957 hasPublicationYear "1999" @default.
• W329750957 type Work @default.
• W329750957 sameAs 329750957 @default.
• W329750957 citedByCount "36" @default.
• W329750957 countsByYear W3297509572012 @default.
• W329750957 countsByYear W3297509572013 @default.
• W329750957 countsByYear W3297509572014 @default.
• W329750957 countsByYear W3297509572015 @default.
• W329750957 countsByYear W3297509572016 @default.
• W329750957 countsByYear W3297509572017 @default.
• W329750957 countsByYear W3297509572019 @default.
• W329750957 countsByYear W3297509572020 @default.
• W329750957 countsByYear W3297509572021 @default.
• W329750957 countsByYear W3297509572022 @default.
• W329750957 crossrefType "journal-article" @default.
• W329750957 hasAuthorship W329750957A5034221146 @default.
• W329750957 hasAuthorship W329750957A5034450243 @default.
• W329750957 hasAuthorship W329750957A5037049833 @default.
• W329750957 hasAuthorship W329750957A5069357139 @default.
• W329750957 hasConcept C109159458 @default.
• W329750957 hasConcept C126322002 @default.
• W329750957 hasConcept C134018914 @default.
• W329750957 hasConcept C170493617 @default.
• W329750957 hasConcept C202751555 @default.
• W329750957 hasConcept C203014093 @default.
• W329750957 hasConcept C2776142715 @default.
• W329750957 hasConcept C2776694085 @default.
• W329750957 hasConcept C2777478134 @default.
• W329750957 hasConcept C2777767877 @default.
• W329750957 hasConcept C2777928079 @default.
• W329750957 hasConcept C2777983669 @default.
• W329750957 hasConcept C2778690821 @default.
• W329750957 hasConcept C28328180 @default.
• W329750957 hasConcept C54355233 @default.
• W329750957 hasConcept C55493867 @default.
• W329750957 hasConcept C71924100 @default.
• W329750957 hasConcept C86803240 @default.
• W329750957 hasConcept C880424 @default.
• W329750957 hasConceptScore W329750957C109159458 @default.
• W329750957 hasConceptScore W329750957C126322002 @default.
• W329750957 hasConceptScore W329750957C134018914 @default.
• W329750957 hasConceptScore W329750957C170493617 @default.
• W329750957 hasConceptScore W329750957C202751555 @default.
• W329750957 hasConceptScore W329750957C203014093 @default.
• W329750957 hasConceptScore W329750957C2776142715 @default.
• W329750957 hasConceptScore W329750957C2776694085 @default.
• W329750957 hasConceptScore W329750957C2777478134 @default.
• W329750957 hasConceptScore W329750957C2777767877 @default.
• W329750957 hasConceptScore W329750957C2777928079 @default.
• W329750957 hasConceptScore W329750957C2777983669 @default.
• W329750957 hasConceptScore W329750957C2778690821 @default.
• W329750957 hasConceptScore W329750957C28328180 @default.
• W329750957 hasConceptScore W329750957C54355233 @default.
• W329750957 hasConceptScore W329750957C55493867 @default.
• W329750957 hasConceptScore W329750957C71924100 @default.
• W329750957 hasConceptScore W329750957C86803240 @default.
• W329750957 hasConceptScore W329750957C880424 @default.
• W329750957 hasIssue "5" @default.
• W329750957 hasLocation W3297509571 @default.
• W329750957 hasOpenAccess W329750957 @default.
• W329750957 hasPrimaryLocation W3297509571 @default.
• W329750957 hasRelatedWork W2018403723 @default.
• W329750957 hasRelatedWork W2149181464 @default.
• W329750957 hasRelatedWork W2244211797 @default.
• W329750957 hasRelatedWork W2262355130 @default.
• W329750957 hasRelatedWork W2315559067 @default.
• W329750957 hasRelatedWork W2407244203 @default.
• W329750957 hasRelatedWork W2442527959 @default.
• W329750957 hasRelatedWork W303228700 @default.

• next