FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W330869641> ?p ?o ?g. }

• W330869641 endingPage "338" @default.
• W330869641 startingPage "334" @default.
• W330869641 abstract "The human sebocyte model offers several advantages over the current animal models. Foremost among these is the correlation of in vitro activity with clinical results, which was not true for arotinoids in the animal models. It is also possible to study several parameters (total cell number, [3H]thymidine uptake, protein and lipid composition/synthesis, hormone response, receptor regulation, etc.) in the same system. The proliferation of isolated sebocytes is inhibited by retinoids, such as isotretinoin and tretinoin, which are known to be clinically active in human acne. Sebocytes are not responsive to the arotinoid temarotene, which is active in the aforementioned animal models and against dimethylbenz[a]anthracene (DMBA)-induced rat mammary carcinoma21,22 but inactive clinically in acne.5,6 Additionally, this model is not responsive to etretinate, a compound known to be active in psoriasis but inactive in acne.23 The in vitro model is, therefore, more predicative of clinical efficacy than the animal models alone." @default.
• W330869641 created "2016-06-24" @default.
• W330869641 creator A5038463946 @default.
• W330869641 creator A5073991681 @default.
• W330869641 date "1990-01-01" @default.
• W330869641 modified "2023-09-27" @default.
• W330869641 title "Retinoid effects on sebocyte proliferation" @default.
• W330869641 cites W1967855722 @default.
• W330869641 cites W1968311977 @default.
• W330869641 cites W1973340566 @default.
• W330869641 cites W1981033632 @default.
• W330869641 cites W1982420762 @default.
• W330869641 cites W1983657407 @default.
• W330869641 cites W1984497928 @default.
• W330869641 cites W1992700022 @default.
• W330869641 cites W1997557809 @default.
• W330869641 cites W2003899150 @default.
• W330869641 cites W2016830496 @default.
• W330869641 cites W2031747135 @default.
• W330869641 cites W2049043712 @default.
• W330869641 cites W2050858509 @default.
• W330869641 cites W2059708706 @default.
• W330869641 cites W2063054744 @default.
• W330869641 cites W2065271969 @default.
• W330869641 cites W4242484835 @default.
• W330869641 cites W4244396289 @default.
• W330869641 doi "https://doi.org/10.1016/0076-6879(90)90038-3" @default.
• W330869641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2087185" @default.
• W330869641 hasPublicationYear "1990" @default.
• W330869641 type Work @default.
• W330869641 sameAs 330869641 @default.
• W330869641 citedByCount "15" @default.
• W330869641 countsByYear W3308696412012 @default.
• W330869641 countsByYear W3308696412014 @default.
• W330869641 countsByYear W3308696412015 @default.
• W330869641 countsByYear W3308696412016 @default.
• W330869641 countsByYear W3308696412022 @default.
• W330869641 crossrefType "book-chapter" @default.
• W330869641 hasAuthorship W330869641A5038463946 @default.
• W330869641 hasAuthorship W330869641A5073991681 @default.
• W330869641 hasConcept C104317684 @default.
• W330869641 hasConcept C121608353 @default.
• W330869641 hasConcept C126322002 @default.
• W330869641 hasConcept C134018914 @default.
• W330869641 hasConcept C16005928 @default.
• W330869641 hasConcept C172268261 @default.
• W330869641 hasConcept C185592680 @default.
• W330869641 hasConcept C202751555 @default.
• W330869641 hasConcept C203014093 @default.
• W330869641 hasConcept C2775954498 @default.
• W330869641 hasConcept C2776260934 @default.
• W330869641 hasConcept C2776285725 @default.
• W330869641 hasConcept C2776705134 @default.
• W330869641 hasConcept C2777673923 @default.
• W330869641 hasConcept C2778117688 @default.
• W330869641 hasConcept C2778938436 @default.
• W330869641 hasConcept C2780564577 @default.
• W330869641 hasConcept C2781121885 @default.
• W330869641 hasConcept C502942594 @default.
• W330869641 hasConcept C55493867 @default.
• W330869641 hasConcept C555283112 @default.
• W330869641 hasConcept C62112901 @default.
• W330869641 hasConcept C71924100 @default.
• W330869641 hasConcept C98274493 @default.
• W330869641 hasConceptScore W330869641C104317684 @default.
• W330869641 hasConceptScore W330869641C121608353 @default.
• W330869641 hasConceptScore W330869641C126322002 @default.
• W330869641 hasConceptScore W330869641C134018914 @default.
• W330869641 hasConceptScore W330869641C16005928 @default.
• W330869641 hasConceptScore W330869641C172268261 @default.
• W330869641 hasConceptScore W330869641C185592680 @default.
• W330869641 hasConceptScore W330869641C202751555 @default.
• W330869641 hasConceptScore W330869641C203014093 @default.
• W330869641 hasConceptScore W330869641C2775954498 @default.
• W330869641 hasConceptScore W330869641C2776260934 @default.
• W330869641 hasConceptScore W330869641C2776285725 @default.
• W330869641 hasConceptScore W330869641C2776705134 @default.
• W330869641 hasConceptScore W330869641C2777673923 @default.
• W330869641 hasConceptScore W330869641C2778117688 @default.
• W330869641 hasConceptScore W330869641C2778938436 @default.
• W330869641 hasConceptScore W330869641C2780564577 @default.
• W330869641 hasConceptScore W330869641C2781121885 @default.
• W330869641 hasConceptScore W330869641C502942594 @default.
• W330869641 hasConceptScore W330869641C55493867 @default.
• W330869641 hasConceptScore W330869641C555283112 @default.
• W330869641 hasConceptScore W330869641C62112901 @default.
• W330869641 hasConceptScore W330869641C71924100 @default.
• W330869641 hasConceptScore W330869641C98274493 @default.
• W330869641 hasLocation W3308696411 @default.
• W330869641 hasLocation W3308696412 @default.
• W330869641 hasOpenAccess W330869641 @default.
• W330869641 hasPrimaryLocation W3308696411 @default.
• W330869641 hasRelatedWork W1973340566 @default.
• W330869641 hasRelatedWork W1989037081 @default.
• W330869641 hasRelatedWork W2025832366 @default.
• W330869641 hasRelatedWork W2066851739 @default.
• W330869641 hasRelatedWork W2091657880 @default.
• W330869641 hasRelatedWork W2093352675 @default.

• next