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• W33184476 abstract "Cellular heterogeneity is a distinctive feature of high-grade gliomas [1]. What are the cellular mechanisms that give rise to the collection of cell types that comprise glioblastoma multiforme? According to the clonal evolution model of tumor heterogeneity (also known as the stochastic model), tumor initiation occurs by an induced change in a single previously normal cell (Fig. 3.1a) [2]. This neoplastic cell has a selective growth advantage compared with the surrounding normal cells." @default.
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• W33184476 date "2010-11-20" @default.
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• W33184476 title "Cellular Origins of Malignant Glioma: The Cancer Stem Cell Polemic" @default.
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• W33184476 doi "https://doi.org/10.1007/978-1-60761-166-0_3" @default.
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