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- W332510157 abstract "The chemical synthesis of peptides, performed either in solution or via solid-phase techniques, relies heavily upon efficient peptide coupling reagents. These agents enhance coupling yields, reduce racemization, and allow reduced cycle times during peptide synthesis. In particular, benzotriazole-based peptide coupling reagents, as activators or additives, are widely used in peptide bond formation reactions in both solution and solid-phase synthesis. The potential for exposure to these peptide coupling reagents exists during their use in the synthesis of polypeptides in the chemical and pharmaceutical industries, as well as during protein synthesis in the recombinant DNA industry. Inhalation and dermal exposure are the primary routes of exposure." @default.
- W332510157 created "2016-06-24" @default.
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- W332510157 date "2014-01-01" @default.
- W332510157 modified "2023-09-27" @default.
- W332510157 title "Peptide Coupling Agents" @default.
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- W332510157 doi "https://doi.org/10.1016/b978-0-12-386454-3.00642-4" @default.
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