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- W33278536 abstract "Publisher Summary This chapter discusses the need for the integration of two systems and the basic features of a possible comprehensive regulatory circuit. The lysozyme molecule can be operationally divided into carrier and hapten regions. B cells have idiotypic receptors with hapten specificity. There are at least two different helper T cells, one idiotype-specific bearing anti-idiotypes determinants and one bearing carrier-specific receptors. Suppressor T cells have receptors with the same hapten specificity and idiotype as the predominant population of B cells. With this minimal model, which explains a maximum number of cell interactions, the threads of the network can be traced. The long-term regulation of the system is sustained by the activity of the self-limiting idiotype network but at a new level reflecting the influence of antigen." @default.
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- W33278536 date "1980-01-01" @default.
- W33278536 modified "2023-09-27" @default.
- W33278536 title "THE ANTIGEN BRIDGE AND IDIOTYPIC INTERACTIONS AS PARALLEL COMMUNICATION SYSTEMS" @default.
- W33278536 doi "https://doi.org/10.1016/b978-0-12-637140-6.50098-x" @default.
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