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- W333306684 abstract "Objective To observe effects of malachite green (MG) on the development of mouse embryo in vitro. Methods Two-cell mouse embryos were obtained and exposed to different concentrations of MG (0 ng/ml, group A, the control; 10 ng/ml, group B; 100 ng/ml, group C; 1 000 ng/ml, group D). The 2-cell mouse embryo assay was used to determine the 2-cell embryo development to the blastocyst. In addition, at the same concentrations of MG, the human sperm motility assay was used to evaluate the influence of MG on sperm viability. Results At the 8-cell stage, groups C and D showed inhibitory effects when compared with the control (P 0.05). Conclusion MG would have deleterious effects on the development of mouse embryo, and the effects were dose-related. The sperm motility assay could also detect high levels of MG in culture medium." @default.
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- W333306684 date "2014-06-01" @default.
- W333306684 modified "2023-09-23" @default.
- W333306684 title "Effects of Malachite Green on the Development of Mouse Embryo In Vitro" @default.
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- W333306684 doi "https://doi.org/10.7669/j.issn.1001-7844.2014.02.0067" @default.
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