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- W333898957 abstract "Abstract Aim A retrospective study was done to determine the prevalence and clinical profile of Hepatitis B in children following up in pediatric liver clinic at our center. Patients were classified as symptomatic and asymptomatic. Results Thirty-eight (8.4%) of the 452 patients were detected to be Hepatitis B surface Antigen (HBsAg) positive. Twenty five (65%) patients were asymptomatic on presentation. Common clinical features were hepatomegaly in 17 (44.7%) patients, jaundice in 10 (26.3%) patients, fever in 6 (15.8%) and splenomegaly in 6 (15.8%) patients. Seventeen (73.9%) patients who were asymptomatic and none of the symptomatic patients had a previous blood transfusion ( p = 0.001). All cases with hepatitis C co-infection were transfusion recipients ( p = 0.012). Two (18.18%) patients in each group had an HBsAg positive family member. SGOT levels were elevated in 16 (64%) asymptomatic patients and 9 (100%) symptomatic cases ( p = 0.03). However no significant correlation was found between elevated SGPT and either group ( p = 0.07). Conclusion Most of the patients with hepatitis B are asymptomatic on presentation. Blood transfusion is a predisposing factor and almost 30% have a hepatitis C co-infection. A more stringent screening of blood products prior to transfusion and universal immunization should be strictly implemented." @default.
- W333898957 created "2016-06-24" @default.
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- W333898957 date "2015-01-01" @default.
- W333898957 modified "2023-09-25" @default.
- W333898957 title "Clinical profile of hepatitis B in children in western India" @default.
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- W333898957 doi "https://doi.org/10.1016/j.injms.2015.01.005" @default.
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